Fernand Labrie

Publications

Page 1 of 4, showing 50 records out of 165 total, starting on record 1, ending on 50

Publication Category Year
4743. El-Alfy, M., Deloche, C., Azzi, L., Bernard, B.A., Bernerd, F., Coutet, J., Chaussade, V, Martel, C., Leclaire, J., Labrie, F. (2010) Skin responses to topical dehydroepiandrosterone: implications in antiageing treatment? British Journal of Dermatology. 163: 968-976 DHEA 2010
4768. Bhasin, S., Pencina, M., Jasuja, G.K., Travison, T.G., Coviello, A., Orwoll, E., Wang P.Y., Nielson, C., Wu, F., Tajar A., Labrie, F., Vesper, H., Zhang, A., Ulloor, J., Singh, R., D’Agostino, R., Vasan, R.S (2011) Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham heart study and applied to three geographically distinct cohorts. JCEM. 96:2430-2439. DHEA 2011
4770. Labrie, F. (2011) Blockade of all sources of androgens is key to optimal treatment at all stages of prostate cancer: Observations made in the 1980's are the basis of current progress in new drug development.  Prostate Cancer Communication – Choices, 27: 3-10. DHEA 2011
4762. Pye, S.R., Almusalam, B., Boonen, S., Vandershueren, D., Borghs, H., Gielen, E., Adams J.E., Ward, K.A., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K, Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Wu, FCW, .O’Neill, TW, EMAS Study Group (2011) Influence of insulin-like growth factor binding proteins (IGFBP)-1 and IGFBP-3 on bone health: Results from the European Male Ageing Study (EMAS). Calcified Tissue International. 88:503-510. DHEA 2011
4764. Tajar, A., O’Connell, M.D.L., Mitnitski, A.B., O’Neill, T.W., Searle, S.D., Huhtaniemi, I.T., Finn, J.D., Bartfai, G., Boonen, S., Casanueva, F.F., Forti, G., Giwercman, A., Han T.S., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman A.J., Vanderschueren, D., Rockwood, K., Wu, F.C.W., the European Male Aging Study Group (EMAS) (2011) Frailty in relation to variations in hormone levels of the hypothalamic-pituitary-testicular axis in older men: Results from the European Male Aging Study. Journal of the American Geriatrics Society (JAGS). 59: 814-821. DHEA 2011
4772. Boonen, S., Pye, S.R., O’Neill, T.W., Szulc, P., Gielen, E, Borghs H, Verschueren, S., Claessens, F., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Tajar, A., Wu FCW, Vanderschueren, D., EMAS study group (2011) Influence of Bone Remodeling Rate on Quantitative Ultrasound (QUS) Parameters at the Calcaneus and DXA BMDa of the Hip and Spine in Middle Aged and Elderly European Men: The European Male Ageing Study (EMAS). European Journal of Endocrinology. 165:977-986. DHEA 2011
4767. Holliday, K.L., Pye, S.R., Thomson, W., Boonen, S., Borghs, H., Vanderschueren, D., Gielen, E., Huhtaniemi, I.T., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Wu, F.C.W., O’Neill, T.W. and the EMAS study group (2011) The ESR1 (6q25) locus is associated with calcaneal ultrasound parameters and radial volumetric bone mineral density in European men. PLoS ONE 6: e22037. DHEA 2011
4769. O’Connor, D.B., Lee, D.M., Corona, G., Forti, G., Tajar, A., O’Neill, T.W., Pendleton, N., Bartfai, G., Boonen, S., Casanueva, F.F., Finn, J.D., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K., Labrie, F., Lean M.E.J., Punab, M., Silman, A.J., Vanderschueren, D., Wu, F.C.W and EMAS study group (2011) The relationships between sex hormones and sexual function in middle-aged and older European men. JCEM. 96:E1577-E1587. DHEA 2011
4771. Ohlsson, C., Barrett-Connor, E., Bhasin, S., Orwoll, E, Labrie, F., Karlsson, M.K., Ljunggren, Ö., Vandenput, L., Mellström, D., Tivesten Åsa. (2011) High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. Journal of the American College of Cardiology (JACC). 58: 1674-1681. DHEA 2011
4765. Tajar, A., McBeth, J., Lee, D.M., Macfarlane, G.J., Huhtaniemi, I.T., Finn, J.D. Bartfai, G., Boonen, S., Casanueva, F.F., Forti, G., Giwercman, A., Han, T.S., Kula, K, Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Vanderschueren, D., O’Neill, T.W., Wu, F.C.W., EMAS Group (2011) Elevated levels of gonadotrophins but not sex steroids are associated with musculoskeletal pain in middle-aged and older European men. Pain. 152:1495-1501. DHEA 2011
4761. Zhao, G., Lu, L., Luu-The, V., Fan, Z., Labrie, F., Pelletier, G. (2010) Expression of 5alpha-reductase type 1 in breast cancer and adjacent non-malignant tissue: an immunohistochemical study. Horm Mol Biol Clin Invest. 3:411-415. DHEA 2010
4766. Johansson, P., Johansson, J.O., Labrie, F., Mattsson, N., Hansson, O., Blennow, K., Zetterberg, H., Wallin, A., Ohlsson, C., Svensson, J. (2011) Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women. Clinical Endocrinology. 75:301-308. DHEA 2011
4763. Labrie, F. (2011) Editorial: The major role of androgens in prostate cancer and the need for more efficient blockade. Expert Rev. Endocrinol. Metab. 6:313-316. DHEA 2011
4759. Jedel, E., Gustafson, D., Waern, M., Sverrisdottir, Y.B., Landén, M., Janson, P.O., Labrie, F., Ohlsson, C., Stener-Victorin, E. (2011) Sex steroids, insulin sensitivity and sympathetic nerve activity in relation to affective symptoms in women with polycystic ovary syndrome. Psychoneuroendocrinology. 36:1470-1479. DHEA 2011
4745. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, JL., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Berger, L., Gilbert, L., Martel, C., Balser, J. (2011) Intravaginal dehydroepiandrosterone (DHEA, Prasterone), a highly efficient treatment of dyspareunia. Climacteric, 14: 282-288. DHEA 2011
4747. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Martel, C., Balser, J. (2010) Effect of intravaginal DHEA in postmenopausal women with vaginal atrophy and pain at sexual activity (dyspareunia) as most bothersome symptom. Proceedings of the 13th World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI), November 4-7, 2010, Berlin, Germany. Code C440:234-380. DHEA 2010
4750. Labrie, F. (2010) Editorial Comment: Kaliks RA et al. Complete androgen blockade safely allows for delay of cytotoxic chemotherapy in castration refractory prostate cancer. International Braz J Urol. 36: 306-307 DHEA 2010
4749. Labrie, F. (2010) Intravaginal DHEA, by a strictly local action, exerts beneficial effects on both vaginal atrophy symptoms and sexual dysfunction. Horm Mol Biol Clin Invest. 4: 499-507 DHEA 2010
4753. Labrie, F. (2011) Blockade of testicular and adrenal androgens in prostate cancer treatment. Nature Reviews. 8: 73-80 DHEA 2011
4757. Labrie, F. (2011) Editorial: Impact of circulating DHEA on androgen formation in women. Menopause, 18: 471-473. DHEA 2011
4756. Labrie, F. Martel, C., Balser, J. (2011) Letters to the Editor - Intracrine formation from DHEA versus ovarian secretion of testosterone. Menopause, 18: 587-591. DHEA 2011
4760. Ward, K.A., Pye, S.R., Adams, J.E., Boonen, S., Vanderschueren, D., Borghs, H., Gaytant, J., Gielen, E., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman A.J., Wu, F.C.W., O’Neill, T.W., The EMAS study group (2011) Influence of age and sex steroids on bone density and geometry in middle-aged and elderly European men. Osteoporos Int. 22:1513-1523. DHEA 2011
4754. Labrie, F (2011) DHEA and Cancer Risk or Prevention? In: DHEA (Dehydroepiandrosterone) in Human Health and Aging, R.R.Watson ed., Taylor & Francis Group LLC, publishers, Chapter 12, pp: 153-172. DHEA 2011
4746. Brotto, L.A., Petkau, A.J., Labrie, F., Basson, R. (2011) Predictors of sexual desire disorders in women. Journal of Sexual Medicine. 8:742-753 DHEA 2011
4732. Lee, D., Ulubaev, A., Tajar, A., Pye, S., Pendleton, N., Purandare, N., O’Neill, T., O’Connor, D., Labrie, F., Platt, H., Payne, D., Bartfai, G., Boonen, S., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I, Kula, K, Lean, M., Punab, M., Silman, A., Vanderschueren, D., Wu, F. (2010) Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study (EMAS). Eur J Endocrinol. 162: 1155-1164. DHEA 2010
4731. Berger, L., E-Alfy, M., Martel, C., Labrie, F. (2010) Effect of long-term topical application of dehydroepiandrosterone (DHEA) and oral estrogens on morphology, cell proliferation, procollagen A1 and androgen receptor levels in rat skin. Horm Mol Biol Clin Invest 2: 267-275. DHEA 2010
4729. Huhtaniemi, I.T., Pye, S.R., Holliday, K.L., Thomson, W., O’Neill, T.W., Platt, H., Payne, D., John, S.L., Jiang, M., Bartfai, G., Boonen, S., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Kula, K, ;Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Vanderschueren, D., Wu, F.C.W. and the EMAS study group (2010) Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men. J Clin Endocrinol Metab. 95:1898-1908. DHEA 2010
4730. Luu-The V, Labrie F. (2010) The intracrine sex steroid biosynthesis pathways. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Neuroendocrinology, Pathological Situations and Diseases,  Progress in Brain Research. Elsevier. Vol 181 (Chapter 10): 2010:177-192. DHEA 2010
4711. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, JL., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Berger, L., Martel, C., Balser, J. (2010) High internal consistency and efficacy of intravaginal DHEA for vaginal atrophy. Gynecological Endocrinology, 26: 524-532. DHEA 2010
4737. Wu, FCW., Tajar, A., T., Beynon, JM., Pye, SR., Silman, AJ., Finn, JD., O’Neill, TW., Bartfai, G., Casanueva, FF., Forti, G., Giwercman, A., Han, TS., Kula, K, Lean, MEJ., Vanderschueren, D., Labrie, F., Huhtaniemi, IT.,  (2010) Identification of late-onset hypogonadism in middle-aged and elderly men. New England Journal of Medicine. 363:123-135. DHEA 2010
4734. Labrie, F. (2010) DHEA, important source of sex steroid in men and even more in women. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 4, Vol. 182 97-148. DHEA 2010
4735. Labrie, F. (2010) Hormonal therapy of prostate cancer. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 14, Vol. 182 321-341. DHEA 2010
4736. Labrie, F., Martel, C., Balser, J. (2011) Wide distribution of the serum levels of DHEA and sex steroids in postmenopausal women – role of the ovary? Menopause. 18:30-43. DHEA 2011
4741. Ohlsson, C., Labrie, F., Barrett-Connor, E., Karlsson, M.K., Ljunggren, Ö., Vandenput, L., Mellström, D., Tivesten, Å. (2010) Low serum levels of dehydroepiandrosterone sulphate predict all-cause and cardiovascular mortality in elderly Swedish men. J Clin Endocrinol Metab. 95: 4406-4414. DHEA 2010
4739. Orwoll, E.S., Nielson, C.M., Labrie, F., Barrett-Connor, E., Cauley, J.A., Cummings, S.R., Ensrud, K., Karlsson, M., Lau, E., Leung, P.C., Lunggren, Ö., Mellström, D., Patrick, A.L., Stefanick, M.L., Nakamura, K., Yoshimura, N., Zmuda, J., Vandenput, L, Ohlsson, C.,for the Osteoporotic Fractures in Men (MrOS) Research Group (2010) Evidence for Geographical and racial variation in serum sex steroid levels in older men. J Clin Endocrinol Metab. 95: E151-E160. DHEA 2010
4744. Jedel, E., Labrie, F., Odén, A., Holm G., Nilsson, L., Janson, P.O., Lind, A.K., Ohlsson, C., Stener-Victorin, E. (2011) Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhoea in women with polycystic ovary syndrome: A randomized controlled trial. Am J Physiol Endocrinol & Metab. 300:E37-E45. DHEA 2011
4722. Vanderschueren, D., Pye, S.R., Venken, K., Borghs, H., Gaytant, J., Huhtaniemi, I.T., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A, Han, T.S., Kula, K., Labrie, F., Lean, M.E., Pendleton, N., Punab, M., Silman, A.J., Wu, F.C, O’Neill, T.W, Boonen, S., The EMAS Study Group (2010) Gonadal sex steroid status and bone health in middle-aged and elderly European men. Osteoporosis Int. 21:1331-1339. DHEA 2010
581. Azzi, L., El-Alfy, M., Martel, C., Labrie, F. (2005) Gender differences in mouse skin morphology and specific effects of sex steroids and dehydroepiandrosterone. J Invest Dermatol, 124: 22-7. DHEA 2005
121. Bélanger, A., Candas, B., Dupont, A., Cusan, L., Diamond, P., Gomez, J.L., Labrie, F. (1994) Changes in serum concentration of conjugated and unconjugated steroids in 40- to 80-year old men. J. Clin. Endocrinol. Metab., 79: 1086-1090. DHEA 1994
178. Bélanger, B., Bélanger, A., Labrie, F., Dupont, A., Cusan, L., Monfette, G. (1989) Comparison of residual C-19 steroids in plasma and prostatic tissue of human, rat and guinea pig after castration: unique importance of extratesticular androgens in men. J. Steroid Biochem., 32: 695-698. DHEA 1989
4718. Basson, R., Brotto, L.A., Petkau, A.J., Labrie, F. (2010) Role of androgens in women's sexual dysfunction. Menopause. 17: 962-971. DHEA 2010
568. Bellemare, V., Labrie, F., Luu-The, V. (2006) Isolation and characterization of a cDNA encoding mouse 3beta-hydroxysteroid dehydrogenase an androgen-inactivating enzyme selectively expressed in female tissues. J Steroid Biochem Mol Biol, 98: 18-24. DHEA 2006
373. Berger, L., El-Alfy, M., Labrie, F. (2008) Effects of intravaginal dehydroepiandrosterone on vaginal histomorphology, sex steroid receptor expression and cell proliferation in the rat. J Steroid Biochem Mol Biol, 109: 67-80. DHEA 2008
358. Berger, L., El-Alfy, M., Martel, C., Labrie, F. (2005) Effects of DHEA, Premarin and Acolbifene on histomorphology and sex steroid receptors of the rat vagina. J Steroid Biochem Mol Biol, 96: 201-15. DHEA 2005
605. Boivin, R.P., Luu-The, V., Lachance, R., Labrie, F., Poirier, D. (2000) Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase. J. Med. Chem., 43: 4465-4478. DHEA 2000
56. Boivin, R.P., Poirier, D., Labrie, F. (1999) 17alpha-alkan (or alkyn) amide derivatives of estradiol as inhibitors of steroid-sulfatase activity. Steroids, 64: 825-833. DHEA 1999
4693. Calvo, E., Luu-The, V., Morissette, J., Martel, C., Labrie, C., Bernard, B., Bernerd, F., Deloche, C., Chaussade, V., Leclaire, J., Labrie, F., (2008) Pangenomic Changes Induced by DHEA in the Skin of Postmenopausal Women. J Steroid Biochem Mol Biol, 112: 186-193 DHEA 2008
569. Chouinard, S., Tessier, M., Vernouillet, G., Gauthier, S., Labrie, F., Barbier, O., Bélanger, A. (2006) Inactivation of the pure antiestrogen Fulvestrant and other synthetic estrogen molecules by UGT1A enzymes expressed in the breast tissue. Mol Pharmacol, 69: 908-20. DHEA 2006
591. Ciobanu, L.C., Luu-The, V., Martel, C., Labrie, F., Poirier, D. (2003) Inhibition of estrone sulfate-induced uterine growth by potent nonestrogenic steroidal inhibitors of steroid sulfatase. Cancer Res., 63: 6442-6446. DHEA 2003
570. Compère, V., Ouellet, J., Luu-The, V., Dureuil, B., Tonon, M.C., Vaudry, H., Labrie, F., Pelletier, G. (2006) Role of androgens and glucocorticoids in the regulation of diazepam-binding inhibitor mRNA levels in male mouse hypothalamus. Brain Res. 1119: 50-7. DHEA 2006
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