Fernand Labrie

Publications

Page 3 of 4, showing 50 records out of 165 total, starting on record 101, ending on 150

Publication Category Year
374. Labrie, F. (2008) Combination of Breast Cancer Prevention with Tissue-Targeted Hormone Replacement Therapy, In: Breast Cancer - Prognosis, Treatment, and Prevention, Second Edition, Pasqualini, J.R., ed., pp. 201-252. DHEA 2008
376. Pelletier, G., Labrie, C., Martel, C., Labrie, F. (2008) Chronic administration of dehydroepiandrosterone (DHEA) to female monkey and rat has no effect on mammary gland histology. J Steroid Biochem Mol Biol, 108: 102-108. DHEA 2008
556. Labrie, F., Cusan, L., Gomez, J.L., Martel, C., Bérubé, R., Bélanger, P., Chaussade, V., Deloche, C., Leclaire, J. (2008) Changes in serum DHEA and eleven of its metabolites during 12-month percutaneous administration of DHEA. J Steroid Biochem Mol Biol, 110: 1-9. DHEA 2008
1087. Labrie, F., Cusan, L., Gomez, J.L., Côté, I., Bérubé, R., Bélanger, P., Martel, C., Labrie, C. (2008) Effect of Intravaginal DHEA on Serum DHEA and Eleven of its Metabolites in Postmenopausal Women. J Steroid Biochem Mol Biol, 111: 178-194 DHEA 2008
4685. Faucher, F., Cantin, L., Luu-The, V., Labrie, F., Breton, F. (2008) The crystal structure of human delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. Biochemistry, 47: 8261-8270. DHEA 2008
4686. Mellström, D., Vandenput, L., Mallmin, H., Holmberg, AH., Lorentzon, M., Odén, A., Johansson, H., Orwoll, ES., Labrie, F., Karlsson, MK., Ljunggren, Ö., Ohlsson C. (2008) Older men with low serum estradiol and high serum SHBG have an increased risk of fractures. J Bone Miner Res, 23: 1552-1560. DHEA 2008
4690. Labrie, F., Cusan, L., Gomez, J.L., Côté, I., Bérubé, R., Bélanger, P., Martel, C., Labrie, C. (2008) Corrigendum to: Effect of Intravaginal DHEA on Serum DHEA and Eleven of its Metabolites in Postmenopausal Women. J Steroid Biochem Mol Biol, 112: 169 DHEA 2008
4693. Calvo, E., Luu-The, V., Morissette, J., Martel, C., Labrie, C., Bernard, B., Bernerd, F., Deloche, C., Chaussade, V., Leclaire, J., Labrie, F., (2008) Pangenomic Changes Induced by DHEA in the Skin of Postmenopausal Women. J Steroid Biochem Mol Biol, 112: 186-193 DHEA 2008
4697. Faucher, F., Cantin, L., Luu-The, V., Labrie, F., Breton, F. (2008) Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition. Biochemistry, 47: 13537-13546. DHEA 2008
1. Bydal, P., Luu-The, V., Labrie, F., Poirier, D. (2009) Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: Chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities. Eur J Med Chem.44:632-644. DHEA 2009
353. Labrie, F., Cusan, L., Gomez, J.L., Côté, I., Bérubé, R., Bélanger, P., Martel, C., Labrie, C. (2009) Effect of One-Week Treatment with Vaginal Estrogen Preparations on Serum Estrogen Levels in Postmenopausal Women. Menopause, 16: 30-36. DHEA 2009
4683. Spitz, I.M., Chertin, B., Fridmans, A., Farkas, A., Bélanger, A., Hartman, H., Labrie, F. (2009). Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists. Prostate Cancer Prostatic Dis, 12: 100-103. DHEA 2009
4692. Labrie, F., Cusan, L., Gomez, J.L., Martel, C., Bérubé, R., Bélanger, P., Bélanger, A., Vandenput, L., Mellström, D., Ohlsson, C. (2009) Comparable Amounts of Sex Steroids are Made Outside the Gonads in Men and Women: Strong Lesson for Hormone Therapy of Prostate and Breast Cancer, JSBMB, 113: 52-56. DHEA 2009
4696. Eriksson, A.L., Lorentzon, M., Vandenput, L., Labrie, F., Lindersson, M., Syvänen, A.C., Orwoll, E.S., Cummings, S.R., Zmuda, J.M., Ljunggren, O., Karlsson, M.K., Mellström, D., Ohlsson, C. (2009) Genetic Variations in Sex Steroid-Related Genes as Predictors of Serum Estrogen Levels in Men. J. Clin Endocrinol, Metab, 94: 1033-1041. DHEA 2009
4700. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, J.L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I., Labrie, C., Lavoie, L., Berger, L., Gilbert, L, Balser, J. (2009) Effect of intravaginal dehydroepiandrosterone (Prasterone) on libido and sexual dysfunction in postmenopausal women, Menopause, 16: 923-931. DHEA 2009
4701. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, J.L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I., Labrie, C., Lavoie, L., Berger, L., Gilbert, L, Martel, C., Balser, J. (2009) Intravaginal dehydroepiandrosterone (Prasterone), a physiological and highly efficient treatment of vaginal atrophy, Menopause, 16: 907-922. DHEA 2009
4702. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, J.L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I., Labrie, C., Lavoie, L., Berger, L., Gilbert, L, Martel, C., Balser, J. (2009) Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration, Menopause, 16: 897-906. DHEA 2009
4703. Forsblad d'Elia, H., Carlsten, H., Labrie, F., Konttinen, Y., Ohlsson, C. (2009) Low serum levels of sex-steroids are associated with disease characteristics in primary Sjögren's syndrome; supplementation with dehydroepiandrosterone restores the concentrations, J Clin Endocrinol Metab, 94: 2044-51. DHEA 2009
4704. Tivesten, A., Vandenput, L., Labrie, F., Karlsson, M.K., Ljunggren, O., Mellström, D., Ohlsson, C. (2009) Low serum testosterone and estradiol predict mortality in elderly men. J Clin Endocrinol Metab, 94: 2482-2488. DHEA 2009
4706. Luu-The, V., Duche, D., Ferraris, C., Meunier, J.R., Leclaire, J., Labrie, F. (2009) Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models EpiskinTM and RealskinTM. J of Ster Biochem and Mol Biol, 116: 178-186. DHEA 2009
4709. Samson, M., Labrie, F., Luu-The, V. (2009) Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line. J Steroid Biochem Mol Biol, 116: 154-159. DHEA 2009
4708. Samson, M., Labrie, F., Zouboulis, C.C., Luu-The, V. (2010) Biosynthesis of dihydrotestosterone by a pathway that does not require testosterone as intermediate in the SZ95 sebaceous gland cell line. J Invest Derm. 130:602-604 DHEA 2010
4710. Labrie, F. (2010) DHEA after Menopause – Sole source of sex steroids and potential sex steroid deficiency treatment. Menopause Management. 19: 14-24 DHEA 2010
4711. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, JL., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Berger, L., Martel, C., Balser, J. (2010) High internal consistency and efficacy of intravaginal DHEA for vaginal atrophy. Gynecological Endocrinology, 26: 524-532. DHEA 2010
4713. Stener-Victorin, E., Holm, G., Labrie, F., Nilsson, L., Janson, P.O., Ohlsson C. (2010) Are there any sensitive and specific sex steroid markers for polycystic ovary syndrome? J Clin Endocrinol Metab, 95: 810-819. DHEA 2010
4718. Basson, R., Brotto, L.A., Petkau, A.J., Labrie, F. (2010) Role of androgens in women's sexual dysfunction. Menopause. 17: 962-971. DHEA 2010
4719. Weirman, M.E., Nappi, R.E., Avis, N., Davis, S.R., Labrie F., Rosner, W., Shifren J.L. (2010) Endocrine aspects of women's sexual function. J Sex Med. 7:561-585. DHEA 2010
4734. Labrie, F. (2010) DHEA, important source of sex steroid in men and even more in women. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 4, Vol. 182 97-148. DHEA 2010
4729. Huhtaniemi, I.T., Pye, S.R., Holliday, K.L., Thomson, W., O’Neill, T.W., Platt, H., Payne, D., John, S.L., Jiang, M., Bartfai, G., Boonen, S., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Kula, K, ;Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Vanderschueren, D., Wu, F.C.W. and the EMAS study group (2010) Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men. J Clin Endocrinol Metab. 95:1898-1908. DHEA 2010
4721. Vandenput, L., Mellström, D, Karlsson, MK., Orwoll, E., Labrie, F., Ljunggren, O., Ohlsson C (2010) Serum estradiol is associated with lean mass in elderly Swedish men. European Journal of Endocrinology. 162: 737-745. DHEA 2010
4722. Vanderschueren, D., Pye, S.R., Venken, K., Borghs, H., Gaytant, J., Huhtaniemi, I.T., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A, Han, T.S., Kula, K., Labrie, F., Lean, M.E., Pendleton, N., Punab, M., Silman, A.J., Wu, F.C, O’Neill, T.W, Boonen, S., The EMAS Study Group (2010) Gonadal sex steroid status and bone health in middle-aged and elderly European men. Osteoporosis Int. 21:1331-1339. DHEA 2010
4723. Samson, M., Labrie, F., Luu-The, V. (2010) Sequential transformation of 4-androstenedione into dihydrotestosterone in prostate carcinoma (DU-145) cells indicates that 4-androstenedione and not testosterone is the substrate of 5alpha-reductase. Horm Mol Clin Invest. 1: 67-72. DHEA 2010
4730. Luu-The V, Labrie F. (2010) The intracrine sex steroid biosynthesis pathways. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Neuroendocrinology, Pathological Situations and Diseases,  Progress in Brain Research. Elsevier. Vol 181 (Chapter 10): 2010:177-192. DHEA 2010
4731. Berger, L., E-Alfy, M., Martel, C., Labrie, F. (2010) Effect of long-term topical application of dehydroepiandrosterone (DHEA) and oral estrogens on morphology, cell proliferation, procollagen A1 and androgen receptor levels in rat skin. Horm Mol Biol Clin Invest 2: 267-275. DHEA 2010
4732. Lee, D., Ulubaev, A., Tajar, A., Pye, S., Pendleton, N., Purandare, N., O’Neill, T., O’Connor, D., Labrie, F., Platt, H., Payne, D., Bartfai, G., Boonen, S., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I, Kula, K, Lean, M., Punab, M., Silman, A., Vanderschueren, D., Wu, F. (2010) Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study (EMAS). Eur J Endocrinol. 162: 1155-1164. DHEA 2010
4735. Labrie, F. (2010) Hormonal therapy of prostate cancer. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 14, Vol. 182 321-341. DHEA 2010
4737. Wu, FCW., Tajar, A., T., Beynon, JM., Pye, SR., Silman, AJ., Finn, JD., O’Neill, TW., Bartfai, G., Casanueva, FF., Forti, G., Giwercman, A., Han, TS., Kula, K, Lean, MEJ., Vanderschueren, D., Labrie, F., Huhtaniemi, IT.,  (2010) Identification of late-onset hypogonadism in middle-aged and elderly men. New England Journal of Medicine. 363:123-135. DHEA 2010
4739. Orwoll, E.S., Nielson, C.M., Labrie, F., Barrett-Connor, E., Cauley, J.A., Cummings, S.R., Ensrud, K., Karlsson, M., Lau, E., Leung, P.C., Lunggren, Ö., Mellström, D., Patrick, A.L., Stefanick, M.L., Nakamura, K., Yoshimura, N., Zmuda, J., Vandenput, L, Ohlsson, C.,for the Osteoporotic Fractures in Men (MrOS) Research Group (2010) Evidence for Geographical and racial variation in serum sex steroid levels in older men. J Clin Endocrinol Metab. 95: E151-E160. DHEA 2010
4741. Ohlsson, C., Labrie, F., Barrett-Connor, E., Karlsson, M.K., Ljunggren, Ö., Vandenput, L., Mellström, D., Tivesten, Å. (2010) Low serum levels of dehydroepiandrosterone sulphate predict all-cause and cardiovascular mortality in elderly Swedish men. J Clin Endocrinol Metab. 95: 4406-4414. DHEA 2010
4743. El-Alfy, M., Deloche, C., Azzi, L., Bernard, B.A., Bernerd, F., Coutet, J., Chaussade, V, Martel, C., Leclaire, J., Labrie, F. (2010) Skin responses to topical dehydroepiandrosterone: implications in antiageing treatment? British Journal of Dermatology. 163: 968-976 DHEA 2010
4747. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Martel, C., Balser, J. (2010) Effect of intravaginal DHEA in postmenopausal women with vaginal atrophy and pain at sexual activity (dyspareunia) as most bothersome symptom. Proceedings of the 13th World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI), November 4-7, 2010, Berlin, Germany. Code C440:234-380. DHEA 2010
4750. Labrie, F. (2010) Editorial Comment: Kaliks RA et al. Complete androgen blockade safely allows for delay of cytotoxic chemotherapy in castration refractory prostate cancer. International Braz J Urol. 36: 306-307 DHEA 2010
4749. Labrie, F. (2010) Intravaginal DHEA, by a strictly local action, exerts beneficial effects on both vaginal atrophy symptoms and sexual dysfunction. Horm Mol Biol Clin Invest. 4: 499-507 DHEA 2010
4761. Zhao, G., Lu, L., Luu-The, V., Fan, Z., Labrie, F., Pelletier, G. (2010) Expression of 5alpha-reductase type 1 in breast cancer and adjacent non-malignant tissue: an immunohistochemical study. Horm Mol Biol Clin Invest. 3:411-415. DHEA 2010
4766. Johansson, P., Johansson, J.O., Labrie, F., Mattsson, N., Hansson, O., Blennow, K., Zetterberg, H., Wallin, A., Ohlsson, C., Svensson, J. (2011) Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women. Clinical Endocrinology. 75:301-308. DHEA 2011
4736. Labrie, F., Martel, C., Balser, J. (2011) Wide distribution of the serum levels of DHEA and sex steroids in postmenopausal women – role of the ovary? Menopause. 18:30-43. DHEA 2011
4744. Jedel, E., Labrie, F., Odén, A., Holm G., Nilsson, L., Janson, P.O., Lind, A.K., Ohlsson, C., Stener-Victorin, E. (2011) Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhoea in women with polycystic ovary syndrome: A randomized controlled trial. Am J Physiol Endocrinol & Metab. 300:E37-E45. DHEA 2011
4745. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, JL., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Berger, L., Gilbert, L., Martel, C., Balser, J. (2011) Intravaginal dehydroepiandrosterone (DHEA, Prasterone), a highly efficient treatment of dyspareunia. Climacteric, 14: 282-288. DHEA 2011
4746. Brotto, L.A., Petkau, A.J., Labrie, F., Basson, R. (2011) Predictors of sexual desire disorders in women. Journal of Sexual Medicine. 8:742-753 DHEA 2011
4753. Labrie, F. (2011) Blockade of testicular and adrenal androgens in prostate cancer treatment. Nature Reviews. 8: 73-80 DHEA 2011
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