Fernand Labrie

Publications

Page 1 of 9, showing 50 records out of 429 total, starting on record 1, ending on 50

Publication Category Year
4768. Bhasin, S., Pencina, M., Jasuja, G.K., Travison, T.G., Coviello, A., Orwoll, E., Wang P.Y., Nielson, C., Wu, F., Tajar A., Labrie, F., Vesper, H., Zhang, A., Ulloor, J., Singh, R., D’Agostino, R., Vasan, R.S (2011) Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham heart study and applied to three geographically distinct cohorts. JCEM. 96:2430-2439. Intracrinology 2011
4772. Boonen, S., Pye, S.R., O’Neill, T.W., Szulc, P., Gielen, E, Borghs H, Verschueren, S., Claessens, F., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Tajar, A., Wu FCW, Vanderschueren, D., EMAS study group (2011) Influence of Bone Remodeling Rate on Quantitative Ultrasound (QUS) Parameters at the Calcaneus and DXA BMDa of the Hip and Spine in Middle Aged and Elderly European Men: The European Male Ageing Study (EMAS). European Journal of Endocrinology. 165:977-986. Intracrinology 2011
4746. Brotto, L.A., Petkau, A.J., Labrie, F., Basson, R. (2011) Predictors of sexual desire disorders in women. Journal of Sexual Medicine. 8:742-753 Intracrinology 2011
4767. Holliday, K.L., Pye, S.R., Thomson, W., Boonen, S., Borghs, H., Vanderschueren, D., Gielen, E., Huhtaniemi, I.T., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Wu, F.C.W., O’Neill, T.W. and the EMAS study group (2011) The ESR1 (6q25) locus is associated with calcaneal ultrasound parameters and radial volumetric bone mineral density in European men. PLoS ONE 6: e22037. Intracrinology 2011
4759. Jedel, E., Gustafson, D., Waern, M., Sverrisdottir, Y.B., Landén, M., Janson, P.O., Labrie, F., Ohlsson, C., Stener-Victorin, E. (2011) Sex steroids, insulin sensitivity and sympathetic nerve activity in relation to affective symptoms in women with polycystic ovary syndrome. Psychoneuroendocrinology. 36:1470-1479. Intracrinology 2011
4744. Jedel, E., Labrie, F., Odén, A., Holm G., Nilsson, L., Janson, P.O., Lind, A.K., Ohlsson, C., Stener-Victorin, E. (2011) Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhoea in women with polycystic ovary syndrome: A randomized controlled trial. Am J Physiol Endocrinol & Metab. 300:E37-E45. Intracrinology 2011
4766. Johansson, P., Johansson, J.O., Labrie, F., Mattsson, N., Hansson, O., Blennow, K., Zetterberg, H., Wallin, A., Ohlsson, C., Svensson, J. (2011) Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women. Clinical Endocrinology. 75:301-308. Intracrinology 2011
4754. Labrie, F (2011) DHEA and Cancer Risk or Prevention? In: DHEA (Dehydroepiandrosterone) in Human Health and Aging, R.R.Watson ed., Taylor & Francis Group LLC, publishers, Chapter 12, pp: 153-172. Intracrinology 2011
4770. Labrie, F. (2011) Blockade of all sources of androgens is key to optimal treatment at all stages of prostate cancer: Observations made in the 1980's are the basis of current progress in new drug development.  Prostate Cancer Communication – Choices, 27: 3-10. Intracrinology 2011
4753. Labrie, F. (2011) Blockade of testicular and adrenal androgens in prostate cancer treatment. Nature Reviews. 8: 73-80 Intracrinology 2011
4757. Labrie, F. (2011) Editorial: Impact of circulating DHEA on androgen formation in women. Menopause, 18: 471-473. Intracrinology 2011
4763. Labrie, F. (2011) Editorial: The major role of androgens in prostate cancer and the need for more efficient blockade. Expert Rev. Endocrinol. Metab. 6:313-316. Intracrinology 2011
4756. Labrie, F. Martel, C., Balser, J. (2011) Letters to the Editor - Intracrine formation from DHEA versus ovarian secretion of testosterone. Menopause, 18: 587-591. Intracrinology 2011
4745. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, JL., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Berger, L., Gilbert, L., Martel, C., Balser, J. (2011) Intravaginal dehydroepiandrosterone (DHEA, Prasterone), a highly efficient treatment of dyspareunia. Climacteric, 14: 282-288. Intracrinology 2011
4736. Labrie, F., Martel, C., Balser, J. (2011) Wide distribution of the serum levels of DHEA and sex steroids in postmenopausal women – role of the ovary? Menopause. 18:30-43. Intracrinology 2011
4755. Lu, L., Zhao, G., Luu-The, V., Ouellet, J., Fan, Z., Labrie, F., Pelletier, G. (2011) Expression of 11β-hydroxysteroid dehydrogenase Type 1 in breast cancer and adjacent non-malignant tissue. An immunocytochemical study. Pathol Oncol Res. 17:627-632. Intracrinology 2011
4769. O’Connor, D.B., Lee, D.M., Corona, G., Forti, G., Tajar, A., O’Neill, T.W., Pendleton, N., Bartfai, G., Boonen, S., Casanueva, F.F., Finn, J.D., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K., Labrie, F., Lean M.E.J., Punab, M., Silman, A.J., Vanderschueren, D., Wu, F.C.W and EMAS study group (2011) The relationships between sex hormones and sexual function in middle-aged and older European men. JCEM. 96:E1577-E1587. Intracrinology 2011
4771. Ohlsson, C., Barrett-Connor, E., Bhasin, S., Orwoll, E, Labrie, F., Karlsson, M.K., Ljunggren, Ö., Vandenput, L., Mellström, D., Tivesten Åsa. (2011) High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. Journal of the American College of Cardiology (JACC). 58: 1674-1681. Intracrinology 2011
4762. Pye, S.R., Almusalam, B., Boonen, S., Vandershueren, D., Borghs, H., Gielen, E., Adams J.E., Ward, K.A., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K, Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Wu, FCW, .O’Neill, TW, EMAS Study Group (2011) Influence of insulin-like growth factor binding proteins (IGFBP)-1 and IGFBP-3 on bone health: Results from the European Male Ageing Study (EMAS). Calcified Tissue International. 88:503-510. Intracrinology 2011
4765. Tajar, A., McBeth, J., Lee, D.M., Macfarlane, G.J., Huhtaniemi, I.T., Finn, J.D. Bartfai, G., Boonen, S., Casanueva, F.F., Forti, G., Giwercman, A., Han, T.S., Kula, K, Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Vanderschueren, D., O’Neill, T.W., Wu, F.C.W., EMAS Group (2011) Elevated levels of gonadotrophins but not sex steroids are associated with musculoskeletal pain in middle-aged and older European men. Pain. 152:1495-1501. Intracrinology 2011
4764. Tajar, A., O’Connell, M.D.L., Mitnitski, A.B., O’Neill, T.W., Searle, S.D., Huhtaniemi, I.T., Finn, J.D., Bartfai, G., Boonen, S., Casanueva, F.F., Forti, G., Giwercman, A., Han T.S., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman A.J., Vanderschueren, D., Rockwood, K., Wu, F.C.W., the European Male Aging Study Group (EMAS) (2011) Frailty in relation to variations in hormone levels of the hypothalamic-pituitary-testicular axis in older men: Results from the European Male Aging Study. Journal of the American Geriatrics Society (JAGS). 59: 814-821. Intracrinology 2011
4760. Ward, K.A., Pye, S.R., Adams, J.E., Boonen, S., Vanderschueren, D., Borghs, H., Gaytant, J., Gielen, E., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Huhtaniemi, I.T., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Silman A.J., Wu, F.C.W., O’Neill, T.W., The EMAS study group (2011) Influence of age and sex steroids on bone density and geometry in middle-aged and elderly European men. Osteoporos Int. 22:1513-1523. Intracrinology 2011
4718. Basson, R., Brotto, L.A., Petkau, A.J., Labrie, F. (2010) Role of androgens in women's sexual dysfunction. Menopause. 17: 962-971. Intracrinology 2010
4731. Berger, L., E-Alfy, M., Martel, C., Labrie, F. (2010) Effect of long-term topical application of dehydroepiandrosterone (DHEA) and oral estrogens on morphology, cell proliferation, procollagen A1 and androgen receptor levels in rat skin. Horm Mol Biol Clin Invest 2: 267-275. Intracrinology 2010
4743. El-Alfy, M., Deloche, C., Azzi, L., Bernard, B.A., Bernerd, F., Coutet, J., Chaussade, V, Martel, C., Leclaire, J., Labrie, F. (2010) Skin responses to topical dehydroepiandrosterone: implications in antiageing treatment? British Journal of Dermatology. 163: 968-976 Intracrinology 2010
4729. Huhtaniemi, I.T., Pye, S.R., Holliday, K.L., Thomson, W., O’Neill, T.W., Platt, H., Payne, D., John, S.L., Jiang, M., Bartfai, G., Boonen, S., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Kula, K, ;Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Vanderschueren, D., Wu, F.C.W. and the EMAS study group (2010) Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men. J Clin Endocrinol Metab. 95:1898-1908. Intracrinology 2010
4710. Labrie, F. (2010) DHEA after Menopause – Sole source of sex steroids and potential sex steroid deficiency treatment. Menopause Management. 19: 14-24 Intracrinology 2010
4734. Labrie, F. (2010) DHEA, important source of sex steroid in men and even more in women. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 4, Vol. 182 97-148. Intracrinology 2010
4750. Labrie, F. (2010) Editorial Comment: Kaliks RA et al. Complete androgen blockade safely allows for delay of cytotoxic chemotherapy in castration refractory prostate cancer. International Braz J Urol. 36: 306-307 Intracrinology 2010
4735. Labrie, F. (2010) Hormonal therapy of prostate cancer. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 14, Vol. 182 321-341. Intracrinology 2010
4749. Labrie, F. (2010) Intravaginal DHEA, by a strictly local action, exerts beneficial effects on both vaginal atrophy symptoms and sexual dysfunction. Horm Mol Biol Clin Invest. 4: 499-507 Intracrinology 2010
4747. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Martel, C., Balser, J. (2010) Effect of intravaginal DHEA in postmenopausal women with vaginal atrophy and pain at sexual activity (dyspareunia) as most bothersome symptom. Proceedings of the 13th World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI), November 4-7, 2010, Berlin, Germany. Code C440:234-380. Intracrinology 2010
4711. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, JL., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Berger, L., Martel, C., Balser, J. (2010) High internal consistency and efficacy of intravaginal DHEA for vaginal atrophy. Gynecological Endocrinology, 26: 524-532. Intracrinology 2010
4712. Labrie, F., Martel, C., Gauthier, S., Pelletier, G., Sancéau JY. (2010) Effect of toremifene and ospemifene, compared to acolbifene, on estrogen-sensitive parameters in rat and human uterine tissues, Horm Mol Biol Clin Invest, 1: 139-146. Intracrinology 2010
4732. Lee, D., Ulubaev, A., Tajar, A., Pye, S., Pendleton, N., Purandare, N., O’Neill, T., O’Connor, D., Labrie, F., Platt, H., Payne, D., Bartfai, G., Boonen, S., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I, Kula, K, Lean, M., Punab, M., Silman, A., Vanderschueren, D., Wu, F. (2010) Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study (EMAS). Eur J Endocrinol. 162: 1155-1164. Intracrinology 2010
4733. Li, S., Han, B., Liu, G., Li, S., Ouellet, J., Labrie, F., Pelletier, G. (2010) Immunocytochemical localization of sex steroid hormone receptors in normal human mammary gland. J Histochem Cytochem. 58:509-15. Intracrinology 2010
4730. Luu-The V, Labrie F. (2010) The intracrine sex steroid biosynthesis pathways. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Neuroendocrinology, Pathological Situations and Diseases,  Progress in Brain Research. Elsevier. Vol 181 (Chapter 10): 2010:177-192. Intracrinology 2010
4741. Ohlsson, C., Labrie, F., Barrett-Connor, E., Karlsson, M.K., Ljunggren, Ö., Vandenput, L., Mellström, D., Tivesten, Å. (2010) Low serum levels of dehydroepiandrosterone sulphate predict all-cause and cardiovascular mortality in elderly Swedish men. J Clin Endocrinol Metab. 95: 4406-4414. Intracrinology 2010
4739. Orwoll, E.S., Nielson, C.M., Labrie, F., Barrett-Connor, E., Cauley, J.A., Cummings, S.R., Ensrud, K., Karlsson, M., Lau, E., Leung, P.C., Lunggren, Ö., Mellström, D., Patrick, A.L., Stefanick, M.L., Nakamura, K., Yoshimura, N., Zmuda, J., Vandenput, L, Ohlsson, C.,for the Osteoporotic Fractures in Men (MrOS) Research Group (2010) Evidence for Geographical and racial variation in serum sex steroid levels in older men. J Clin Endocrinol Metab. 95: E151-E160. Intracrinology 2010
4723. Samson, M., Labrie, F., Luu-The, V. (2010) Sequential transformation of 4-androstenedione into dihydrotestosterone in prostate carcinoma (DU-145) cells indicates that 4-androstenedione and not testosterone is the substrate of 5alpha-reductase. Horm Mol Clin Invest. 1: 67-72. Intracrinology 2010
4708. Samson, M., Labrie, F., Zouboulis, C.C., Luu-The, V. (2010) Biosynthesis of dihydrotestosterone by a pathway that does not require testosterone as intermediate in the SZ95 sebaceous gland cell line. J Invest Derm. 130:602-604 Intracrinology 2010
4713. Stener-Victorin, E., Holm, G., Labrie, F., Nilsson, L., Janson, P.O., Ohlsson C. (2010) Are there any sensitive and specific sex steroid markers for polycystic ovary syndrome? J Clin Endocrinol Metab, 95: 810-819. Intracrinology 2010
4728. Tajar, A., Forti, G., O’Neill, T.W., Lee, D.M., Silman A.J., Finn, J.D., Bartfai, G., Boonen, S., Casaneuva, F.F., Giwercman, A. Han, T.S., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Vanderschueren, D., Huhtaniemi, I.T., Wu, F.C.W., and the EMAS Group (2010) Characteristics of secondary, primary and compensated hypogonadism in ageing men: Evidence from the European male ageing study (EMAS). J Clin Endocrinol Metab. 95:1810-1818. Intracrinology 2010
4721. Vandenput, L., Mellström, D, Karlsson, MK., Orwoll, E., Labrie, F., Ljunggren, O., Ohlsson C (2010) Serum estradiol is associated with lean mass in elderly Swedish men. European Journal of Endocrinology. 162: 737-745. Intracrinology 2010
4722. Vanderschueren, D., Pye, S.R., Venken, K., Borghs, H., Gaytant, J., Huhtaniemi, I.T., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A, Han, T.S., Kula, K., Labrie, F., Lean, M.E., Pendleton, N., Punab, M., Silman, A.J., Wu, F.C, O’Neill, T.W, Boonen, S., The EMAS Study Group (2010) Gonadal sex steroid status and bone health in middle-aged and elderly European men. Osteoporosis Int. 21:1331-1339. Intracrinology 2010
4719. Weirman, M.E., Nappi, R.E., Avis, N., Davis, S.R., Labrie F., Rosner, W., Shifren J.L. (2010) Endocrine aspects of women's sexual function. J Sex Med. 7:561-585. Intracrinology 2010
4737. Wu, FCW., Tajar, A., T., Beynon, JM., Pye, SR., Silman, AJ., Finn, JD., O’Neill, TW., Bartfai, G., Casanueva, FF., Forti, G., Giwercman, A., Han, TS., Kula, K, Lean, MEJ., Vanderschueren, D., Labrie, F., Huhtaniemi, IT.,  (2010) Identification of late-onset hypogonadism in middle-aged and elderly men. New England Journal of Medicine. 363:123-135. Intracrinology 2010
4758. Yamana, K., Labrie, F., Luu-The, V (2010) Human type 3 5alpha-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride, Horm Mol Biol Clin Invest. 2:293-299. Intracrinology 2010
4761. Zhao, G., Lu, L., Luu-The, V., Fan, Z., Labrie, F., Pelletier, G. (2010) Expression of 5alpha-reductase type 1 in breast cancer and adjacent non-malignant tissue: an immunohistochemical study. Horm Mol Biol Clin Invest. 3:411-415. Intracrinology 2010
1. Bydal, P., Luu-The, V., Labrie, F., Poirier, D. (2009) Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: Chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities. Eur J Med Chem.44:632-644. Intracrinology 2009
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