Fernand Labrie

Publications

Page 2 of 9, showing 50 records out of 429 total, starting on record 51, ending on 100

Publication Category Year
4696. Eriksson, A.L., Lorentzon, M., Vandenput, L., Labrie, F., Lindersson, M., Syvänen, A.C., Orwoll, E.S., Cummings, S.R., Zmuda, J.M., Ljunggren, O., Karlsson, M.K., Mellström, D., Ohlsson, C. (2009) Genetic Variations in Sex Steroid-Related Genes as Predictors of Serum Estrogen Levels in Men. J. Clin Endocrinol, Metab, 94: 1033-1041. Intracrinology 2009
4703. Forsblad d'Elia, H., Carlsten, H., Labrie, F., Konttinen, Y., Ohlsson, C. (2009) Low serum levels of sex-steroids are associated with disease characteristics in primary Sjögren's syndrome; supplementation with dehydroepiandrosterone restores the concentrations, J Clin Endocrinol Metab, 94: 2044-51. Intracrinology 2009
4682. Ivanga, M., Labrie, Y., Calvo, E., Belleau, P., Martel, C., Pelletier, G., Morissette, J., Labrie, F., Durocher, F. (2009) Fine temporal analysis of DHT transcriptional modulation of the ATM/Gadd45g signaling pathways in the mouse uterus. Mol Reprod Dev, 76:278-288. Intracrinology 2009
4700. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, J.L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I., Labrie, C., Lavoie, L., Berger, L., Gilbert, L, Balser, J. (2009) Effect of intravaginal dehydroepiandrosterone (Prasterone) on libido and sexual dysfunction in postmenopausal women, Menopause, 16: 923-931. Intracrinology 2009
4701. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, J.L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I., Labrie, C., Lavoie, L., Berger, L., Gilbert, L, Martel, C., Balser, J. (2009) Intravaginal dehydroepiandrosterone (Prasterone), a physiological and highly efficient treatment of vaginal atrophy, Menopause, 16: 907-922. Intracrinology 2009
4702. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, J.L., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I., Labrie, C., Lavoie, L., Berger, L., Gilbert, L, Martel, C., Balser, J. (2009) Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration, Menopause, 16: 897-906. Intracrinology 2009
353. Labrie, F., Cusan, L., Gomez, J.L., Côté, I., Bérubé, R., Bélanger, P., Martel, C., Labrie, C. (2009) Effect of One-Week Treatment with Vaginal Estrogen Preparations on Serum Estrogen Levels in Postmenopausal Women. Menopause, 16: 30-36. Intracrinology 2009
4692. Labrie, F., Cusan, L., Gomez, J.L., Martel, C., Bérubé, R., Bélanger, P., Bélanger, A., Vandenput, L., Mellström, D., Ohlsson, C. (2009) Comparable Amounts of Sex Steroids are Made Outside the Gonads in Men and Women: Strong Lesson for Hormone Therapy of Prostate and Breast Cancer, JSBMB, 113: 52-56. Intracrinology 2009
4698. Li, Z., Luu-The, V., Poisson-Paré, D., Ouellet, J., Li, S., Labrie, F., Pelletier, G. (2009) Expression of enzymes involved in synthesis and metabolism of estradiol in human breast as studied by immunocytochemistry and in situ hybridization. Histol Histopathol, 24: 273-282. Intracrinology 2009
4706. Luu-The, V., Duche, D., Ferraris, C., Meunier, J.R., Leclaire, J., Labrie, F. (2009) Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models EpiskinTM and RealskinTM. J of Ster Biochem and Mol Biol, 116: 178-186. Intracrinology 2009
4709. Samson, M., Labrie, F., Luu-The, V. (2009) Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line. J Steroid Biochem Mol Biol, 116: 154-159. Intracrinology 2009
4683. Spitz, I.M., Chertin, B., Fridmans, A., Farkas, A., Bélanger, A., Hartman, H., Labrie, F. (2009). Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists. Prostate Cancer Prostatic Dis, 12: 100-103. Intracrinology 2009
4704. Tivesten, A., Vandenput, L., Labrie, F., Karlsson, M.K., Ljunggren, O., Mellström, D., Ohlsson, C. (2009) Low serum testosterone and estradiol predict mortality in elderly men. J Clin Endocrinol Metab, 94: 2482-2488. Intracrinology 2009
373. Berger, L., El-Alfy, M., Labrie, F. (2008) Effects of intravaginal dehydroepiandrosterone on vaginal histomorphology, sex steroid receptor expression and cell proliferation in the rat. J Steroid Biochem Mol Biol, 109: 67-80. Intracrinology 2008
4693. Calvo, E., Luu-The, V., Morissette, J., Martel, C., Labrie, C., Bernard, B., Bernerd, F., Deloche, C., Chaussade, V., Leclaire, J., Labrie, F., (2008) Pangenomic Changes Induced by DHEA in the Skin of Postmenopausal Women. J Steroid Biochem Mol Biol, 112: 186-193 Intracrinology 2008
4697. Faucher, F., Cantin, L., Luu-The, V., Labrie, F., Breton, F. (2008) Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition. Biochemistry, 47: 13537-13546. Intracrinology 2008
4685. Faucher, F., Cantin, L., Luu-The, V., Labrie, F., Breton, F. (2008) The crystal structure of human delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. Biochemistry, 47: 8261-8270. Intracrinology 2008
4691. Han, B., Li, S., Song, D., Poisson-Paré, D., Liu, G., Luu-The, V., Ouellet, J., Li, S., Labrie, F., Pelletier, G. (2008) Expression of 17beta-hydroxysteroid dehydrogenase type 2 and type 5 in breast cancer and adjacent non-malignant tissue: a correlation to clinicopathological parameters. J Steroid Biochem Mol Biol, 112: 194-200 Intracrinology 2008
374. Labrie, F. (2008) Combination of Breast Cancer Prevention with Tissue-Targeted Hormone Replacement Therapy, In: Breast Cancer - Prognosis, Treatment, and Prevention, Second Edition, Pasqualini, J.R., ed., pp. 201-252. Intracrinology 2008
2. Labrie, F. (2008) Preface. Best Pract Res Clin Endocrinol Metab, 22: pp. vii-ix. Intracrinology 2008
4690. Labrie, F., Cusan, L., Gomez, J.L., Côté, I., Bérubé, R., Bélanger, P., Martel, C., Labrie, C. (2008) Corrigendum to: Effect of Intravaginal DHEA on Serum DHEA and Eleven of its Metabolites in Postmenopausal Women. J Steroid Biochem Mol Biol, 112: 169 Intracrinology 2008
1087. Labrie, F., Cusan, L., Gomez, J.L., Côté, I., Bérubé, R., Bélanger, P., Martel, C., Labrie, C. (2008) Effect of Intravaginal DHEA on Serum DHEA and Eleven of its Metabolites in Postmenopausal Women. J Steroid Biochem Mol Biol, 111: 178-194 Intracrinology 2008
556. Labrie, F., Cusan, L., Gomez, J.L., Martel, C., Bérubé, R., Bélanger, P., Chaussade, V., Deloche, C., Leclaire, J. (2008) Changes in serum DHEA and eleven of its metabolites during 12-month percutaneous administration of DHEA. J Steroid Biochem Mol Biol, 110: 1-9. Intracrinology 2008
725. Labrie, F., Koutsilieris, M. (2008) The 12th International Congress on Hormonal Steroids and Hormones & Cancer. J Steroid Biochem Mol Biol, 108: 179. Intracrinology 2008
4687. Ma, C., Yoshioka, M., Boivin, A., Belleau, P., Gan, L., Takase, Y., Labrie, F., St-Amand, J. (2008) Erratum: Prostate specific genes and their regulation by dihydrotestosterone. Prostate, 68: 1372. Intracrinology 2008
4. Ma, C., Yoshioka, M., Boivin, A., Belleau, P., Gan, L., Takase, Y., Labrie, F., St-Amand, J. (2008) Prostate specific genes and their regulation by dihydrotestosterone. Prostate, 68: 241-254. Intracrinology 2008
4686. Mellström, D., Vandenput, L., Mallmin, H., Holmberg, AH., Lorentzon, M., Odén, A., Johansson, H., Orwoll, ES., Labrie, F., Karlsson, MK., Ljunggren, Ö., Ohlsson C. (2008) Older men with low serum estradiol and high serum SHBG have an increased risk of fractures. J Bone Miner Res, 23: 1552-1560. Intracrinology 2008
376. Pelletier, G., Labrie, C., Martel, C., Labrie, F. (2008) Chronic administration of dehydroepiandrosterone (DHEA) to female monkey and rat has no effect on mammary gland histology. J Steroid Biochem Mol Biol, 108: 102-108. Intracrinology 2008
4684. Zhang, Y., Calvo, E., Martel, C., Luu-The, V., Labrie, F., Tchernof, A. (2008) Response of the adipose tissue transcriptome to dihydrotestosterone in mice. Physiol Genomics 35: 254-261 Intracrinology 2008
5. Akaza, H., Labrie, F., Namiki, M. (2007) [A way of thinking of a MAB therapy for local/locally advanced prostate cancer: the theory and recent evaluation]. Gan To Kagaku Ryoho. Jpn J Cancer Chemotherapy, 34: 657-669. Intracrinology 2007
729. Faucher, F., Cantin, L., Pereira de Jésus-Tran, K., Lemieux, M., Luu-The, V., Labrie, F., Breton, R. (2007) Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding. J. Mol. Biol., 369: 525-540. Intracrinology 2007
730. Ivanga, M., Labrie, Y., Calvo, E., Belleau, P., Martel, C., Luu-The, V., Morissette, J., Labrie, F., Durocher, F. (2007) Temporal analysis of E2 transcriptional induction of PTP and MKP and downregulation of IGF-I pathway key components in the mouse uterus. Physiol Genomics, 29: 13-23. Intracrinology 2007
355. Labrie, F. (2007) Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy. Nat Clin Pract Endocrinol Metab, 3: 584-93. Intracrinology 2007
7. Labrie, F. (2007) Multiple intracrine hormonal targets in the prostate: oportunities and challenges. BJU Int, 100: 48-51. Intracrinology 2007
559. Labrie, F., Bélanger, A., Bélanger, P., Bérubé, R., Martel, C., Cusan, L., Gomez, J., Candas, B., Chaussade, V., Castiel, I., Deloche, C., Leclaire, J. (2007) Metabolism of DHEA in postmenopausal women following percutaneous administration., 103: 178-88. Intracrinology 2007
560. Labrie, F., Bélanger, A., Labrie, C., Candas, B., Cusan, L., Gomez, J.L. (2007) Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women. J Steroid Biochem Mol Biol, 107: 57-69. Intracrinology 2007
735. Labrie, F., Bélanger, A., Luu-The, V. (2007) Biosynthèse et sécrétion des hormones stéroïdiennes, in: Chanson, P., ed. Traité d'Endocrinologie, Paris: Flammarion Médecine-Sciences, pp 13-19. Intracrinology 2007
561. Liu, H., Bellemare, V., Labrie, F., Luu-The, V. (2007) Molecular characterization of the cynomolgus monkey Macaca fascicularis steroidogenic enzymes belonging to the aldo-keto reductase family. J Steroid Biochem Mol Biol, 104: 75-80. Intracrinology 2007
737. Liu, H., Zheng, S.F., Bellemare, V., Pelletier, G., Labrie, F., Luu-The, V. (2007) Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey. BMC Biochem, 8: 1-9. Intracrinology 2007
356. Luu-The, V., Ferraris, C., Duche, D., Bélanger, P., Leclaire, J., Labrie, F. (2007) Steroid metabolism and profile of steroidogenic gene expression in EpiskinTM: High similarity with human epidermis. J Steroid Biochem Mol Biol 107: 30-36. Intracrinology 2007
4714. Pelletier, G., Li, S., Luu-The, V., Labrie, F. (2007) Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. J Neuroendocrinol, 19: 426-431 Intracrinology 2007
740. Pelletier, G., Luu-The, V., Li, S., Bujold, G., Labrie, F. (2007) Localization and glucocorticoid regulation of 11beta-hydroxysteroid dehydrogenase type 1 mRNA in the male mouse forebrain. Neuroscience, 145: 110-115. Intracrinology 2007
741. Qiu, W., Zhou, M., Mazumdar, M., Azzi, A., Ghanmi, D., Luu-The, V., Labrie, F., Lin, S.-X. (2007) Structure-based inhibitor design for an enzymeTHAT binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol, 282: 8368-79. Intracrinology 2007
10. Suzuki, K., Nishiyama, T., Hara, N., Yamana, K., Takahashi, K., Labrie, F. (2007) Importance of the intracrine metabolism of adrenal androgens in androgen-dependent prostate cancer. Prostate Cancer Prostatic Dis., 10: 301-6. Intracrinology 2007
564. Swanson, C., Lorentzon, M., Vandenput, L., Labrie, F., Rane, A., Jakobsson, J., Chouinard, S., Bélanger, A., Ohlsson, C. (2007) Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y). J Clin Endocrinol Metab, 92: 3697-704. Intracrinology 2007
11. Swanson, C., Mellström, D., Lorentzon, M., Vanderput, L., Jakobsson, J., Rane, A., Karlsson, M., Ljunggren, O., Smith, U., Eriksson, A.E., Bélanger, A., Labrie, F., Ohlsson, C. (2007) The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men. J Clin Endocrinol Metab, 92: 4878-4882. Intracrinology 2007
12. Takase, Y., Luu-The, V., Poisson-Paré, D., Labrie, F., Pelletier, G. (2007) Expression of sulfotransferase 1E1 in human prostate as studied by in situ hybridization and immunocytochemistry. Prostate, 67: 405-409. Intracrinology 2007
14. Vandenput, L., Labrie, F., Mellström, D., Swanson, C., Knutsson, T., Peeker, R., Ljunggren, O., Orwoll, E., Eriksson, A.L., Johnell, O., Damber, J.E., Ohlsson, C. (2007) Serum levels of specific glucuronidated androgen metabolites predict BMD and prostate volume in elderly men. J. of Bone and Mineral Research: The Official Journal of the American Soc. for Bone and Mineral Research, 22: 220-7. Intracrinology 2007
747. Vandenput, L., Mellström, D., Lorentzon, M., Swanson, C., Karlsson, M.K., Brandberg, J., Lönn, L., Orwoll, E., Smith, U., Labrie, F., Ljunggren, O., Tivesten, A., Ohlsson, C. (2007) Androgens and glucuronidated androgen metabolites are associated with metabolic risk factors in men. J Clin Endocrinol Metab, 92: 4130 7. Intracrinology 2007
568. Bellemare, V., Labrie, F., Luu-The, V. (2006) Isolation and characterization of a cDNA encoding mouse 3beta-hydroxysteroid dehydrogenase an androgen-inactivating enzyme selectively expressed in female tissues. J Steroid Biochem Mol Biol, 98: 18-24. Intracrinology 2006
<< previous | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 next >>

Biography  |  Publications  |  Scientific Conferences  |  Selected Slide Presentations  |  Awards