Fernand Labrie

Publications

Page 4 of 9, showing 50 records out of 429 total, starting on record 151, ending on 200

Publication Category Year
450. Blais, Y., Gingras, S., Haagensen, D.E., Labrie, F., Simard, J. (1996). Interleukin-4 and interleukin-13 inhibit estrogen-induced breast cancer cell proliferation and stimulate GCDFP-15 expression in human breast cancer cells. Mol. Cell. Endocrinol., 121: 11-18. Intracrinology 1996
454. Poirier, D., Mérand, Y., Labrie, C., Labrie, F. (1996) D-Ring alkylamide derivatives of estradiol: Effect on ER-binding affinity and antiestrogenic activity. Bioorg. Med. Chem. Lett., 6: 2537-2542. Intracrinology 1996
456. Auger, S., Mérand, Y., Pelletier, J.D., Poirier, D., Labrie, F. (1995) Synthesis and biological activities of thioether derivatives related to the antiestrogens tamoxifen and ICI 164384. J. Steroid Biochem. Mol. Biol., 52: 547-565. Intracrinology 1995
457. Blais, Y., Sugimoto, K., Carrière, M.C., Haagensen, D.E., Labrie, F., Simard, J. (1995) Interleukin-6 inhibits the potent stimulatory action of androgens, glucocorticoids and interleukin-1alpha on apolipoprotein D and GCDFP-15 expression in human breast cancer cells. Int. J. Cancer, 62: 732-737. Intracrinology 1995
459. Labrie, F., Li, S., Labrie, C., Lévesque, C., Mérand, Y. (1995) Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 33: 237-244. Intracrinology 1995
460. Li, S., Lévesque, C., Geng, C.S., Yan, X., Labrie, F. (1995) Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 34: 147-159. Intracrinology 1995
465. Pelletier, J.D., Labrie, F., Poirier, D. (1994) N-butyl, N-methyl, 11-3',17'β-dihydroxy-1'3'5'(10') estratrien-16'α-yl)-9-(R/S)bromo undecanamide: synthesis and 17β-HSD inhibiting activity, estrogenic activity and antiestrogenic activity. Steroids, 59: 536-547. Intracrinology 1994
466. Poirier, D., Auger, S., Mérand, Y., Simard, J., Labrie, F. (1994) Synthesis and antiestrogenic activity of diaryl thioether derivatives. J. Med. Chem., 37: 1115-1125. Intracrinology 1994
468. Couture, P., Thériault, C., Simard, J., Labrie, F. (1993) Androgen receptor-mediated stimulation of 17β-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Endocrinology, 132: 179-185. Intracrinology 1993
470. Li, S., Yan, X., Bélanger, A., Labrie, F. (1993) Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(?)anthracene (DMBA) in the rat. Breast Cancer Res. Treat., 29: 203-217. Intracrinology 1993
473. Labrie, C., Martel, C., Dufour, J.M., Lévesque, C., Mérand, Y., Labrie, F. (1992) Novel compounds inhibit estrogen formation and action. Cancer Res., 52: 610-615. Intracrinology 1992
474. Labrie, F., Simard, J., de Launoit, Y., Poulin, R., Thériault, C., Dumont, M., Dauvois, S., Martel, C., Li, S.; (1992) Androgens and breast cancer. Cancer Detect. Prev., 16: 31-38. Intracrinology 1992
476. Roy, R., Dauvois, S., Labrie, F., Bélanger, A. (1992) Estrogen-stimulated glucuronidation of dihydrotestosterone in MCF-7 human breast cancer cells. J. Steroid Biochem. Mol. Biol., 41: 579-582. Intracrinology 1992
477. Simard, J., de Launoit, Y., Haagensen, D.E., Labrie, F. (1992) Additive stimulatory action of glucocorticoids and androgens on basal and estrogen-repressed apolipoprotein D messenger RNA levels and secretion in human breast cancer cells. Endocrinology, 130: 1115-1121. Intracrinology 1992
478. Dauvois, S., Geng, C.S., Lévesque, C., Mérand, Y., Labrie, F. (1991) Additive inhibitory effects of an androgen and the antiestrogen EM-170 on estradiol-stimulated growth of human ZR-75-1 breast tumors in athymic mice. Cancer Res., 51: 3131-3135. Intracrinology 1991
479. de Launoit, Y., Dauvois, S., Dufour, M., Simard, J., Labrie, F. (1991) Inhibition of cell cycle kinetics and proliferation by the androgen 5α-dihydrotestosterone and antiestrogen N,n-butyl-N-methyl-11-[16'a-chloro-3',17β-dihydroxy-estra-1',3',5'-(10')triene-7'a-yl] undecanamide in human breast cancer ZR-75-1 cells. Cancer Res., 51: 2797-2802. Intracrinology 1991
481. Lévesque, C., Mérand, Y., Dufour, J.M., Labrie, C., Labrie, F. (1991) Synthesis and biological activity of new halo-steroidal antiestrogens. J. Med. Chem., 34: 1624-1630. Intracrinology 1991
485. Bélanger, A., Caron, S., Labrie, F., Naldoni, C., Dogliotti, L., Angeli, A. (1990) Levels of eighteen non-conjugated and conjugated steroids in human breast cyst fluid: Relationships with cyst type. Eur J Cancer, 26: 277-281. Intracrinology 1990
487. Dauvois, S., Labrie, F. (1990) Effect of adrenal estrogens on the growth of dimethylbenz(a)antracene-induced mammary carcinoma in the rat. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F., eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 416-418. Intracrinology 1990
488. Dauvois, S., Li, S., Labrie, F. (1990) Antagonism between androgens and estrogens on the growth of mammary carcinoma in vivo. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F., eds. Steroid Formation, Degradation and Action in Normal, Neoplasic and Peripheral Tissues. Ann. New York Acad. Sci. pp 413-415. Intracrinology 1990
489. Dauvois, S., Simard, J., Dumont, M., Haagensen, D.E., Labrie, F. (1990) Opposite effects of estrogen and the progestin R5020 on cell proliferation and GCDFP-15 expression in ZR-75-1 human breast cancer cells. Mol. Cell. Endocrinol. 73: 171-178. Intracrinology 1990
491. Labrie, F., Poulin, R., Simard, J., Zhao, H., Labrie, C., Dauvois, S., Dumont, M., Hatton, A.C., Poirier, D., Mérand, Y. (1990) Interactions between estrogens, androgens, progestins and glucocorticoids in ZR-75-1 human breast cancer cells. in: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. N.Y. Acad. Sci. 595: 130-148. Intracrinology 1990
492. Labrie, F., Simard, J., Poulin, R., Hatton, A.C., Labrie, C., Dauvois, S., Zhao, H., Petitclerc, L., Couet, J., Dumont, M., Haagensen D.E. (1990) Potent antagonism between estrogens and androgens on GCDFP-15 expression and cell growth in the ZR-75-1 human breast cancer cells. In: Angeli, A., Bradlow, H., Chasalow, F.I. et Dogliotti, L. eds. Workshop on Biochemistry of Breast Cyst Fluid and Cancer Risk. Ann. N.Y. Acad. Sci. 586: 174-187. Intracrinology 1990
493. Laquerre, S., Poulin, R., Labrie, F., Chafouleas, J.G. (1990) Identification of a 51-kilodalton calmodulin binding protein that changes during estrogen-stimulated cell growth. Biochem. Cell Biol., 68: 863-869. Intracrinology 1990
495. Marchetti, B., Labrie, F. (1990) Hormonal regulation of beta-adrenergic receptors in the rat mammary gland during the estrous cycle and lactation: role of sex steroids and prolactin. Endocrinology, 126: 575-581. Intracrinology 1990
496. Poirier, D., Poulin, R., Mérand, Y., Thériault, C., Labrie, F. (1990) High level of esterification of steroids to long-chain fatty acids in ZR-75-1 human breast cancer cells. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 422-424. Intracrinology 1990
498. Poulin, R., Poirier, D., Thériault, C., Couture, J., Bélanger, A., Labrie, F. (1990) Wide spectrum of steroids serving as substrates for the formation of lipoidal derivatives in ZR-75-1 human breast cancer cells. J. Steroid Biochem., 35: 237-247. Intracrinology 1990
499. Simard, J., Dauvois, S., Haagensen, D.E., Lévesque, C., Mérand, Y., Labrie, F. (1990) Regulation of progesterone-binding breast cyst protein GCDFP-24 secretion by estrogens and androgens in human breast cancer cells: a new marker of steroid action in breast cancer. Endocrinology, 126: 3223-3231. Intracrinology 1990
500. Thériault, C., Poulin, R., Tremblay, S., Poirier, D., Labrie, F. (1990) Hormonal regulation of estradiol 17beta-hydroxysteroid dehydrogenase activity in the ZR-75-1 human breast cancer cell line. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 419-421. Intracrinology 1990
502. Dauvois, S., Li, S., Martel, C., Labrie, F. (1989) Inhibitory effect of androgens on DMBA-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 14: 299-306. Intracrinology 1989
504. Dumont, M., Dauvois, S., Simard, J., Garcia, T., Schachter, B., Labrie, F. (1989) Antagonism between estrogens and androgens on GCDFP-15 gene expression in ZR-75-1 cells and correlation between GCDFP-15 and estrogen as well as progesterone receptor expression in human breast cancer. J. Steroid Biochem., 34: 397-402. Intracrinology 1989
506. Poulin, R., Baker, D., Poirier, D., Labrie, F. (1989) Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Breast Cancer Res. Treat., 13: 161-172. Intracrinology 1989
507. Poulin, R., Dufour, J.-M., Labrie, F. (1989) Progestin inhibition of estrogen-dependent proliferation in ZR-75-1 human breast cancer cells: antagonism by insulin. Breast Cancer Res. Treat., 13: 265-276. Intracrinology 1989
508. Poulin, R., Mérand, Y., Poirier, D., Lévesque, C., Dufour, J.M., Labrie, F. (1989) Antiestrogenic properties of keoxifene, trans-4-hydroxytamoxifen and ICI 164384, a new steroidal derivative, in ZR-75-1 human breast cancer cells. Breast Cancer Res. Treat., 14: 65-76. Intracrinology 1989
509. Poulin, R., Poirier, D., Mérand, Y., Thériault, C., Bélanger, A., Labrie, F. (1989) Extensive esterification of adrenal C19-?5 sex steroids to long-chain fatty acids in the ZR-75-1 human breast cancer cell line. J. Biol. Chem., 264: 9335-9343. Intracrinology 1989
510. Poulin, R., Simard, J., Labrie, C., Petitclerc, L., Dumont, M., Lagacé, L., Labrie, F. (1989) Down-regulation of estrogen receptors by androgens in the ZR-75-1 human breast cancer cell line. Endocrinology, 125: 392-399. Intracrinology 1989
511. Simard, J., Hatton, A.-C., Labrie, C., Dauvois, S., Zhao, H., Haagensen, D.E., Labrie, F. (1989) Inhibitory effect of estrogens on GCDFP-15 mRNA levels and secretion in ZR-75-1 human breast cancer cells. Mol. Endocrinol., 3: 694-702. Intracrinology 1989
521. Poulin, R., Baker, D., Labrie, F. (1988) Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line. Breast Cancer Res. Treat., 12: 213-225. Intracrinology 1988
522. Poulin, R., Mérand, Y., Labrie, F. (1988) Antiestrogenic properties of a 7?-alkylated derivative of 17?-estradiol in ZR-75-1 human breast cancer, in: Genazzani, A.R., Petraglia, F., Volpe, A. et Facchinetti, F., eds: Recent Research in Gynecological Endocrinology, Parthenon Publishing Group, pp 631-634. Intracrinology 1988
523. Spinola, P.G., Marchetti, B., Mérand, Y., Labrie, F. (1988) Effects of the aromatase inhibitor 4-hydroxyandrostenedione and antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors. Breast Cancer Res. Treat., 12: 287-296. Intracrinology 1988
556. Labrie, F., Cusan, L., Gomez, J.L., Martel, C., Bérubé, R., Bélanger, P., Chaussade, V., Deloche, C., Leclaire, J. (2008) Changes in serum DHEA and eleven of its metabolites during 12-month percutaneous administration of DHEA. J Steroid Biochem Mol Biol, 110: 1-9. Intracrinology 2008
559. Labrie, F., Bélanger, A., Bélanger, P., Bérubé, R., Martel, C., Cusan, L., Gomez, J., Candas, B., Chaussade, V., Castiel, I., Deloche, C., Leclaire, J. (2007) Metabolism of DHEA in postmenopausal women following percutaneous administration., 103: 178-88. Intracrinology 2007
560. Labrie, F., Bélanger, A., Labrie, C., Candas, B., Cusan, L., Gomez, J.L. (2007) Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women. J Steroid Biochem Mol Biol, 107: 57-69. Intracrinology 2007
561. Liu, H., Bellemare, V., Labrie, F., Luu-The, V. (2007) Molecular characterization of the cynomolgus monkey Macaca fascicularis steroidogenic enzymes belonging to the aldo-keto reductase family. J Steroid Biochem Mol Biol, 104: 75-80. Intracrinology 2007
564. Swanson, C., Lorentzon, M., Vandenput, L., Labrie, F., Rane, A., Jakobsson, J., Chouinard, S., Bélanger, A., Ohlsson, C. (2007) Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y). J Clin Endocrinol Metab, 92: 3697-704. Intracrinology 2007
568. Bellemare, V., Labrie, F., Luu-The, V. (2006) Isolation and characterization of a cDNA encoding mouse 3beta-hydroxysteroid dehydrogenase an androgen-inactivating enzyme selectively expressed in female tissues. J Steroid Biochem Mol Biol, 98: 18-24. Intracrinology 2006
569. Chouinard, S., Tessier, M., Vernouillet, G., Gauthier, S., Labrie, F., Barbier, O., Bélanger, A. (2006) Inactivation of the pure antiestrogen Fulvestrant and other synthetic estrogen molecules by UGT1A enzymes expressed in the breast tissue. Mol Pharmacol, 69: 908-20. Intracrinology 2006
570. Compère, V., Ouellet, J., Luu-The, V., Dureuil, B., Tonon, M.C., Vaudry, H., Labrie, F., Pelletier, G. (2006) Role of androgens and glucocorticoids in the regulation of diazepam-binding inhibitor mRNA levels in male mouse hypothalamus. Brain Res. 1119: 50-7. Intracrinology 2006
571. Eriksson, A.L., Lorentzon, M., Mellstrom, D., Vandenput, L., Swanson, C., andersson, N., Hammond, G.L., Jakobsson, J., Rane, A., Orwoll, E.S., Ljunggren, O., Johnell, O., Labrie, F., Windahl, S.H., Ohlsson, C. (2006) SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density. J Clin Endocrinol Metab, 91: 5029-37. Intracrinology 2006
572. Faucher, F., Pereira de Jésus-Trans, K., Cantin, L., Luu-The, V., Labrie, F., Breton, R. (2006) Crystal structures of mouse 17beta-hydroxysteroid dehydrogenase (Apoenzyme and enzyme-NADP(H) binary complex): Identification of molecular determinants responsible for the unique 17beta-reductive activity of this enzyme. J.Mol. Biol., 364: 747-763. Intracrinology 2006
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