Page 5 of 9, showing 50 records out of 429 total, starting on record 201, ending on 250
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Category |
Year |
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979. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Bélanger, A. (1992) Cloning, expression and regulation of tissue-specific expression of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase in Cellular and Molecular Biology of the Adrenal Cortex, London, John Libbey Eurotext Ltd., pp 89-109. |
Intracrinology |
1992 |
|
980. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Bélanger, A., Lachance, Y., Zhao, H.F., Labrie, C., Breton, N., de Launoit, Y., Dumont, M., Dupont, E., Rhéaume, E., Martel, C., Couët, J., Trudel, C. (1992) Structure and tissue-specific expression of 3β-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. J. Steroid Biochem. Mol. Biol., 41: 421-435. |
Intracrinology |
1992 |
|
935. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Belghmi, K., Bélanger, A. (1994) Structure, regulation and role of 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase and aromatase enzymes in formation of sex steroids in classical and peripheral intracrine tissues, in: Sheppard, M.C. et Stewart, P.M., eds: Hormones, Enzymes and Receptors, London, Baillière's clinical endocrinology and metabolism, pp 451-474. |
Intracrinology |
1994 |
|
963. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Labrie, C., Dupont, E., Martel, C., Couet, J., Trudel, C., Rhéaume, E., Breton, N., de Launoit, Y., Dumont, M., Zhao, H.F., Lachance, Y. (1993) Structure and control of expression of the 3β-HSD and 17β-HSD genes in classical steroidogenic and peripheral intracrine tissues, in: Leung, P.C.K., Hsueh, A.J.W. et Friesen, H.G., eds: Molecular Basis of Reproductive Endocrinology, New York, Karger, pp 112-143. |
Intracrinology |
1993 |
|
1003. Labrie, F., Simard, J., Luu-The, V., Trudel, C., Martel, C., Labrie, C., Zhao, H.F., Rhéaume, E., Couet, J., Breton, N. (1991) Expression of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase (3beta-HSD) and 17beta-hydroxysteroid dehydrogenase (17beta-HSD) in adipose tissue. Int. J. Obstet., 15 Suppl. 2: 91-99. |
Intracrinology |
1991 |
|
492. Labrie, F., Simard, J., Poulin, R., Hatton, A.C., Labrie, C., Dauvois, S., Zhao, H., Petitclerc, L., Couet, J., Dumont, M., Haagensen D.E. (1990) Potent antagonism between estrogens and androgens on GCDFP-15 expression and cell growth in the ZR-75-1 human breast cancer cells. In: Angeli, A., Bradlow, H., Chasalow, F.I. et Dogliotti, L. eds. Workshop on Biochemistry of Breast Cyst Fluid and Cancer Risk. Ann. N.Y. Acad. Sci. 586: 174-187. |
Intracrinology |
1990 |
|
981. Labrie, F., Sugimoto, Y., Luu-The, V., Simard, J., Lachance, Y., Bachvarov, D., Leblanc, G., Durocher, F., Paquet, N. (1992) Structure of human type II 5α-reductase gene. Endocrinology, 131: 1571-1573. |
Intracrinology |
1992 |
|
640. Labrie, Y., Couet, J., Simard, J., Labrie, F. (1994) Multihormonal regulation of dehydroepiandrosterone sulfotransferase mRNA levels in adult rat liver. Endocrinology, 134: 1693-1699. |
Intracrinology |
1994 |
|
908. Labrie, Y., Durocher, F., Lachance, Y., Turgeon, C., Simard, J., Labrie, C., Labrie, F. (1995) The human type II 17beta-hydroxysteroid dehydrogenase gene encodes two alternatively-spliced messenger RNA species. DNA Cell Biol., 14: 849-861. |
Intracrinology |
1995 |
|
1034. Lachance, Y., Luu-The, V., Labrie, C., Simard, J., Dumont, M., de Launoit, Y., Guérin, S., Leblanc, G., Labrie, F. (1990) Characterization of human 3beta-hydroxysteroid dehydrogenase/delta5/delta4-isomerase gene and its expression in mammalian cells. J. Biol. Chem, 265: 20469-20475. |
Intracrinology |
1990 |
|
1004. Lachance, Y., Luu-The, V., Verreault, H., Dumont, M., Rhéaume, E., Leblanc, G., Labrie, F. (1991) Structure of human 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase (3beta-HSD) gene-adrenal and gonadal specificity. DNA Cell Biol., 10: 701-711. |
Intracrinology |
1991 |
|
174. Lacoste, D., Bélanger, A., Labrie, F. (1990) Biosynthesis and degradation of androgens in human prostatic cancer cell lines. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F., eds. Steroid Formation, Degradation and Action in Peripheral Tissues Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 389-391. |
Intracrinology |
1990 |
|
493. Laquerre, S., Poulin, R., Labrie, F., Chafouleas, J.G. (1990) Identification of a 51-kilodalton calmodulin binding protein that changes during estrogen-stimulated cell growth. Biochem. Cell Biol., 68: 863-869. |
Intracrinology |
1990 |
|
460. Li, S., Lévesque, C., Geng, C.S., Yan, X., Labrie, F. (1995) Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 34: 147-159. |
Intracrinology |
1995 |
|
470. Li, S., Yan, X., Bélanger, A., Labrie, F. (1993) Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(?)anthracene (DMBA) in the rat. Breast Cancer Res. Treat., 29: 203-217. |
Intracrinology |
1993 |
|
910. Li, X., Chen, C., Singh, S.M., Labrie, F. (1995) The enzyme and inhibitors of 4-ene-3-oxosteroid 5alpha-reductase. Steroids, 60: 430-441. |
Intracrinology |
1995 |
|
116. Li, X., Singh, S.M., Côté, J., Laplante, S., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro evaluation of 4-substituted-N-(1,1-dimethylethyl)-3-oxo-4-androsten-17beta-carboxamides as 5alpha-reductase inhibitors and antiendrogens. J. Med. Chem., 38: 1456-1461. |
Intracrinology |
1995 |
|
937. Li, X., Singh, S.M., Labrie, F. (1994) Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium (III) chloride: synthesis of 17β-propyl-17β-hydroxy-4-androsten-3-one, an androgen receptor antagonist. Tetrahedron Lett., 35: 1157-1160. |
Intracrinology |
1994 |
|
117. Li, X., Singh, S.M., Labrie, F. (1995) Synthesis and in vitro activity of 17beta-(N-alkyl)formamido/ alkylamido-4-aza-/4-methyl-4-aza-3-oxo-5beta-androstan-3-ones as inhibitors of human 5alpha-reductase and antagonists on the androgen receptor. J. Med. Chem., 38: 1158-1173. |
Intracrinology |
1995 |
|
118. Li, X., Singh, S.M., Lourdusamy, M., Mérand, Y., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro antiandrogenic activity of 17beta-hydroxy-17beta-(w-hydroxy/haloalkyn-1'-yl)-4-methyl-4-aza-3-oxo-5beta-androstan-(1-ene)-3-ones. Bioorg. Med. Chem. Lett., 5: 1061-1064. |
Intracrinology |
1995 |
|
886. Li, X., Singh, S.M., Luu-The, V., Côté, J., Laplante, S., Labrie, F. (1996) Vinyl fluoride as a mimic of the "intermediate" enol form in the 5alpha-reductase transformation: synthesis and in vitro activity of (N-1',1'-dimethylethyl)-3-haloandrost-3,5-diene-17beta-carboxamides. Bioorg. Med. Chem., 4: 55-60. |
Intracrinology |
1996 |
|
4698. Li, Z., Luu-The, V., Poisson-Paré, D., Ouellet, J., Li, S., Labrie, F., Pelletier, G. (2009) Expression of enzymes involved in synthesis and metabolism of estradiol in human breast as studied by immunocytochemistry and in situ hybridization. Histol Histopathol, 24: 273-282. |
Intracrinology |
2009 |
|
982. Lin, S.-X., Yang, F., Jin, J.-Z., Breton, R., Zhu, D.-W., Luu-The, V., Labrie, F. (1992) Subunit identity of the dimeric 17β-hydroxysteroid dehydrogenase from human placenta. J. Biol. Chem., 267: 16182-16187. |
Intracrinology |
1992 |
|
887. Lin, S.-X., Zhu, D.-W., Azzi, A., Campbell, R.L., Breton, R., Labrie, F., Ghosh, D., Pletnev, V., Duax, W.L., Pangborn, W. (1996) Studies on the 3D-structure of estrogenic 17beta-hydroxysteroid dehydrogenase. J. Endocrinol., 150 Suppl.: S13-S20. |
Intracrinology |
1996 |
|
561. Liu, H., Bellemare, V., Labrie, F., Luu-The, V. (2007) Molecular characterization of the cynomolgus monkey Macaca fascicularis steroidogenic enzymes belonging to the aldo-keto reductase family. J Steroid Biochem Mol Biol, 104: 75-80. |
Intracrinology |
2007 |
|
737. Liu, H., Zheng, S.F., Bellemare, V., Pelletier, G., Labrie, F., Luu-The, V. (2007) Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey. BMC Biochem, 8: 1-9. |
Intracrinology |
2007 |
|
888. Lopez-Solache, I., Luu-The, V., Séralini, G.E., Labrie, F. (1996) Heterogeneity of rat type I 5alpha-reductase cDNA: cloning, expression and regulation by pituitary implants and dihydrotestosterone. Biochim. Biophys. Acta, 1305: 139-144. |
Intracrinology |
1996 |
|
857. Lourdusamy, M., Coté, J., Laplante, S., Labrie, F., Singh, S.M. (1997) Synthesis and in vitro Study of 17beta-(N-Ureylne-N, N'-disubstituted)-4-methyl-4Aza-5alpha-androstan-3-ones as Selective Inhibitors of Type I 5alpha-Reductase. Bioorg. Med. Chem., 5: 305-310. |
Intracrinology |
1997 |
|
88. Luo, S., Chen, C., Labrie, C., Candas, B., Singh, S.M., Labrie, F. (1997) Daily dosing with Flutamide or Casodex exerts maximal antiandrogenic activity. Urology, 50: 913-919. |
Intracrinology |
1997 |
|
428. Luo, S., Labrie, C., Bélanger, A., Candas, B., Labrie, F. (1998) Prevention of development of dimenthylbenz(a)anthracene (DMBA)-induced mammary tumors in the rat by the new nonsteroidal antiestrogen EM-800 (SCH 57050). Breast Cancer Res. Treat., 49: 1-11. |
Intracrinology |
1998 |
|
439. Luo, S., Labrie, C., Bélanger, A., Labrie, F. (1997) Effect of dehydroepiandrosterone (DHEA) on bone mass, serum lipids, and dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Endocrinology, 138: 3387-3394. |
Intracrinology |
1997 |
|
440. Luo, S., Martel, C., Gauthier, S., Mérand, Y., Bélanger, A., Labrie, C., Labrie, F. (1997) Long-term inhibitory effects of a novel anti-estrogen on the growth of ZR-75-1 and MCF-7 human breast cancer tumors in nude mice. Int. J. Cancer, 73: 735-739. |
Intracrinology |
1997 |
|
441. Luo, S., Martel, C., Sourla, A., Gauthier, S., Mérand, Y., Bélanger, A., Labrie, C., Labrie, F. (1997) Comparative effects of 28-day treatment with the new antiestrogen EM-800 and tamoxifen on estrogen-sensitive parameters in the intact mouse. Int. J. Cancer, 73: 381-391. |
Intracrinology |
1997 |
|
442. Luo, S., Sourla, A., Labrie, C., Bélanger, A., Labrie, F. (1997) Combined effects of dehydroepiandrosterone and EM-800 on bone mass, serum lipids, and the development of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Endocrinology, 138: 4435-4444. |
Intracrinology |
1997 |
|
429. Luo, S., Sourla, A., Labrie, C., Gauthier, S., Mérand, Y., Bélanger, A., Labrie, F. (1998) Effect of twenty-four-week treatment with the antiestrogen EM-800 on estrogen-sensitive parameters in intact and ovariectomized mice. Endocrinology, 139: 2645-2656. |
Intracrinology |
1998 |
|
443. Luo, S., Stojanovic, M., Labrie, C., Labrie, F. (1997) Inhibitory effect of the novel antiestrogen EM-800 and medroxyprogesterone acetate (MPA) on estrone-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Int. J. Cancer, 73: 580-586. |
Intracrinology |
1997 |
|
889. Luu-The, V., Bernier, F., Dufort, I., Labrie, F. (1996) Molecular biology of steroid sulfotransferase. Ann. N.Y. Acad. Sci., 784: 137-148. |
Intracrinology |
1996 |
|
635. Luu-The, V., Dufort, I., Paquet, N., Reimnitz, G., Labrie, F. (1995) Structural characterization and expression of the human dehydroepiandrosterone sulfotransferase gene. DNA Cell Biol., 14: 511-518. |
Intracrinology |
1995 |
|
781. Luu-The, V., Dufort, I., Pelletier, G., Labrie, F. (2001) Type 5 17beta-hydroxysteroid dehydrogenase: its role in the formation of androgens in women. Mol. Cell. Endocrinol., 171: 77-82. |
Intracrinology |
2001 |
|
356. Luu-The, V., Ferraris, C., Duche, D., Bélanger, P., Leclaire, J., Labrie, F. (2007) Steroid metabolism and profile of steroidogenic gene expression in EpiskinTM: High similarity with human epidermis. J Steroid Biochem Mol Biol 107: 30-36. |
Intracrinology |
2007 |
|
1037. Luu-The, V., Labrie, C., Simard, J., Lachance, Y., Zhao, H.F., Couët, J., Leblanc, G., Labrie, F. (1990) Structure of two in tandem human 17beta-hydroxysteroid dehydrogenase genes. Mol. Endocrinol., 4: 268-275. |
Intracrinology |
1990 |
|
864. Luu-The, V., Simard, J., Labrie, C., Bélanger, A., Labrie, F. (1997) Intracrinology and hormone-dependent cancers. Rev. Clin. Pharmacol., 11: 18-26. |
Intracrinology |
1997 |
|
366. Luu-The, V., Sugimoto, Y., Puy, L., Labrie, Y., Lopez Solache, I., Singh, M., Labrie, F. (1994) Characterization, expression and immunohistochemical localization of 5alpha-reductase in human skin. J. Invest. Dermatol., 102: 221-226. |
Intracrinology |
1994 |
|
1006. Luu-The, V., Takahashi, M., de Launoit, Y., Dumont, M., Lachance, Y., Labrie, F. (1991) Evidence for distinct dehydrogenase and isomerase sites within a single 3beta-hydroxysteroid dehydrogenase 5-ene-4-ene-isomerase protein. Biochemistry, 30: 8861-8865. |
Intracrinology |
1991 |
|
1038. Luu-The, V., Takahashi, M., Labrie, F. (1990) Purification of microsomal and mitochondrial 3beta-hydroxysteroid dehydrogenase/delta4delta5 isomerase from human placenta. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 386-388. |
Intracrinology |
1990 |
|
1007. Luu-The, V., Takahashi, M., Labrie, F. (1991) Differential inhibition of dehydrogenase and 5-ene-4-ene isomerase activities of purified 3beta-hydroxysteroid dehydrogenase. Evidence for two distinct sites. J. Steroid Biochem. Molec. Biol., 40: 545-548. |
Intracrinology |
1991 |
|
383. Luu-The, V., Tremblay, P., Labrie, F. (2006) Characterization of type 12 17beta-hydroxysteroid dehydrogenase (17beta-HSD12), an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women. Molecular Endocrinology (Baltimore, Md.), 20: 437-43. |
Intracrinology |
2006 |
|
915. Luu-The, V., Zhang, Y., Poirier, D., Labrie, F. (1995) Characteristics of human types 1, 2, and 3 17beta-hydroxysteroid dehydrogenase activities: oxidation reduction and inhibition. J. Steroid Biochem. Mol. Biol., 55: 581-587. |
Intracrinology |
1995 |
|
916. Mébarki, F., Sanchez, R., Rhéaume, E., Laflamme, N., Simard, J., Forest, M.G., Bey-Omar, F., David, M., Labrie, F., Morel, Y. (1995) Nonsalt-losing male pseudohermaphroditism due to the novel homozygous N100S mutation in the type II 3beta-hydroxysteroid dehydrogenase (HSD3B2) gene. J. Clin. Endocrinol. Metab., 80: 2127-2134. |
Intracrinology |
1995 |
|
4687. Ma, C., Yoshioka, M., Boivin, A., Belleau, P., Gan, L., Takase, Y., Labrie, F., St-Amand, J. (2008) Erratum: Prostate specific genes and their regulation by dihydrotestosterone. Prostate, 68: 1372. |
Intracrinology |
2008 |