Page 6 of 9, showing 50 records out of 429 total, starting on record 251, ending on 300
| Publication |
Category |
Year |
|
908. Labrie, Y., Durocher, F., Lachance, Y., Turgeon, C., Simard, J., Labrie, C., Labrie, F. (1995) The human type II 17beta-hydroxysteroid dehydrogenase gene encodes two alternatively-spliced messenger RNA species. DNA Cell Biol., 14: 849-861. |
Intracrinology |
1995 |
|
460. Li, S., Lévesque, C., Geng, C.S., Yan, X., Labrie, F. (1995) Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 34: 147-159. |
Intracrinology |
1995 |
|
910. Li, X., Chen, C., Singh, S.M., Labrie, F. (1995) The enzyme and inhibitors of 4-ene-3-oxosteroid 5alpha-reductase. Steroids, 60: 430-441. |
Intracrinology |
1995 |
|
116. Li, X., Singh, S.M., Côté, J., Laplante, S., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro evaluation of 4-substituted-N-(1,1-dimethylethyl)-3-oxo-4-androsten-17beta-carboxamides as 5alpha-reductase inhibitors and antiendrogens. J. Med. Chem., 38: 1456-1461. |
Intracrinology |
1995 |
|
117. Li, X., Singh, S.M., Labrie, F. (1995) Synthesis and in vitro activity of 17beta-(N-alkyl)formamido/ alkylamido-4-aza-/4-methyl-4-aza-3-oxo-5beta-androstan-3-ones as inhibitors of human 5alpha-reductase and antagonists on the androgen receptor. J. Med. Chem., 38: 1158-1173. |
Intracrinology |
1995 |
|
118. Li, X., Singh, S.M., Lourdusamy, M., Mérand, Y., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro antiandrogenic activity of 17beta-hydroxy-17beta-(w-hydroxy/haloalkyn-1'-yl)-4-methyl-4-aza-3-oxo-5beta-androstan-(1-ene)-3-ones. Bioorg. Med. Chem. Lett., 5: 1061-1064. |
Intracrinology |
1995 |
|
635. Luu-The, V., Dufort, I., Paquet, N., Reimnitz, G., Labrie, F. (1995) Structural characterization and expression of the human dehydroepiandrosterone sulfotransferase gene. DNA Cell Biol., 14: 511-518. |
Intracrinology |
1995 |
|
915. Luu-The, V., Zhang, Y., Poirier, D., Labrie, F. (1995) Characteristics of human types 1, 2, and 3 17beta-hydroxysteroid dehydrogenase activities: oxidation reduction and inhibition. J. Steroid Biochem. Mol. Biol., 55: 581-587. |
Intracrinology |
1995 |
|
916. Mébarki, F., Sanchez, R., Rhéaume, E., Laflamme, N., Simard, J., Forest, M.G., Bey-Omar, F., David, M., Labrie, F., Morel, Y. (1995) Nonsalt-losing male pseudohermaphroditism due to the novel homozygous N100S mutation in the type II 3beta-hydroxysteroid dehydrogenase (HSD3B2) gene. J. Clin. Endocrinol. Metab., 80: 2127-2134. |
Intracrinology |
1995 |
|
917. Morissette, J., Rhéaume, E., Leblanc, J.-F., Luu-The, V., Labrie, F., Simard, J. (1995) Genetic linkage mapping of HSD3B1 and HSD3B2 encoding human types I and II 3beta-hydroxysteroid dehydrogenase/delta5-delta4-isomerase close to D1S514 and the centromeric D1Z5 locus. Cytogenet Cell Genet, 69: 59-62. |
Intracrinology |
1995 |
|
918. Pelletier, G., Luu-The, V., Labrie, F. (1995) Immunocytochemical localization of type I 17beta-hydroxysteroid dehydrogenase in the rat brain. Brain Res., 704: 233-239. |
Intracrinology |
1995 |
|
919. Rhéaume, E., Sanchez, R., Mébarki, F., Gagnon, E., Carel, J.C., Chaussain, J.L., Morel, Y., Labrie, F., Simard, J. (1995) Identification and characterization of the G15D mutation found in a male patient with 3beta-hydroxysteroid dehydrogenase (3beta-HSD) deficiency: alteration of the putative NAD-binding domaine of type II 3beta-HSD. Biochemistry, 34: 2893-2900. |
Intracrinology |
1995 |
|
920. Simard, J., Rhéaume, E., Mébarki, F., Sanchez, R., New, M.I., Morel, Y., Labrie, F. (1995) Molecular basis of human 3beta-hydroxysteroid dehydrogenase deficiency. J. Steroid Biochem. Mol. Biol., 53: 127-138. |
Intracrinology |
1995 |
|
921. Simard, J., Sanchez, R., Durocher, F., Rhéaume, E., Turgeon, C., Labrie, Y., Luu-The, V., Mebarki, F., Morel, Y., de Launoit, Y., Labrie, F. (1995) Structure-function relationships and molecular genetics of the 3beta-hydroxysteroid dehydrogenase gene family. J. Steroid Biochem. Mol. Biol., 55: 489-505. |
Intracrinology |
1995 |
|
364. Sugimoto, Y., Lopez-Solache, I., Labrie, F., Luu-The, V. (1995) Cations inhibit specifically Type I 5alpha-reductase found in human skin. J. Invest. Dermatol., 104: 775-778. |
Intracrinology |
1995 |
|
120. Sun, S., Narod, S., Aprikian, A., Ghadirian, P., Labrie, F. (1995) Androgen receptor and familial prostate cancer. Nature Medicine, 1: 848-849. |
Intracrinology |
1995 |
|
924. Zhu, D.-W., Zhou, M., Mao, Y., Labrie, F., Lin, S.-X. (1995) Crystallization of human estrogenic 17beta-hydroxysteroid dehydrogenase under microgravity. J. Cryst. Growth, 156: 108-111. |
Intracrinology |
1995 |
|
121. Bélanger, A., Candas, B., Dupont, A., Cusan, L., Diamond, P., Gomez, J.L., Labrie, F. (1994) Changes in serum concentration of conjugated and unconjugated steroids in 40- to 80-year old men. J. Clin. Endocrinol. Metab., 79: 1086-1090. |
Intracrinology |
1994 |
|
926. Bernier, F., Leblanc, G., Labrie, F., Luu-The, V. (1994) Structure of human estrogen and aryl sulfotransferase gene: Two mRNA species issued from a single gene. J. Biol. Chem., 269: 28200-28205. |
Intracrinology |
1994 |
|
927. Bernier, F., Lopez, I., Labrie, F., Luu-The, V. (1994) Cloning and expression of cDNA encoding human placental estrogen sulfotransferase. Mol. Cell. Endocrinol., 99: R11-R15. |
Intracrinology |
1994 |
|
928. Breton, R., Yang, F., Jin, J.Z., Li, B., Labrie, F., Lin, S.-X. (1994) Human 17beta-hydroxysteroid dehydrogenase: overproduction using a baculovirus expression system and characterization. J. Steroid Biochem. Mol. Biol., 50: 275-282. |
Intracrinology |
1994 |
|
365. Couët, J., Martel, C., Labrie, Y., Luo, S., Simard, J., Labrie, F. (1994) Opposite effects of prolactin and corticosterone on the expression and activity of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in rat skin. J. Invest. Dermatol., 103: 60-64. |
Intracrinology |
1994 |
|
930. Dionne, P., Singh, S.M., Labrie, F. (1994) 1H and 13C nuclear magnetic resonance assignments and stereochemistry of N-n-butyl-n-methyl-11-(16'α-chloro-3',17'β (and 17α)-dihydroxyestra-1',4',5'(10')-trien-7α-yl) undecanamide. Steroids, 59: 493-497. |
Intracrinology |
1994 |
|
931. Dupont, E., Simard, J., Luu-The, V., Labrie, F., Pelletier, G. (1994) Localization of 3β-hydroxysteroid dehydrogenase in rat brain as studied by in situ hybridization. Mol. Cell. Neurosci., 5: 119-123. |
Intracrinology |
1994 |
|
124. Labrie, F. (1994) Intracrinology and Cancer Therapy. Science Watch, 5: 3-4. |
Intracrinology |
1994 |
|
129. Labrie, F., Simard, J., Bélanger, A., Luu-The, V., Labrie, C. (1994) Molecular biology of the intracrine steroidogenic enzymes in the human prostate, in: Motta, M. et Serio, M., eds: Sex Hormones and Antihormones in Endocrine-Dependent Pathology: Basic and Clinical Aspects, New York, Elsevier, pp 77-92. |
Intracrinology |
1994 |
|
934. Labrie, F., Simard, J., Luu-The, V., Pelletier, G. (1994) Molecular genetics, structure-function relationships and tissue-specific expression and tissue-specific expression and regulation of the 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase gene family, in: Bartke, A., ed. Function of Somatic Cells in the Testis, New York, NY, USA, Springer-Verlag, pp 126-150. |
Intracrinology |
1994 |
|
935. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Belghmi, K., Bélanger, A. (1994) Structure, regulation and role of 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase and aromatase enzymes in formation of sex steroids in classical and peripheral intracrine tissues, in: Sheppard, M.C. et Stewart, P.M., eds: Hormones, Enzymes and Receptors, London, Baillière's clinical endocrinology and metabolism, pp 451-474. |
Intracrinology |
1994 |
|
640. Labrie, Y., Couet, J., Simard, J., Labrie, F. (1994) Multihormonal regulation of dehydroepiandrosterone sulfotransferase mRNA levels in adult rat liver. Endocrinology, 134: 1693-1699. |
Intracrinology |
1994 |
|
937. Li, X., Singh, S.M., Labrie, F. (1994) Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium (III) chloride: synthesis of 17β-propyl-17β-hydroxy-4-androsten-3-one, an androgen receptor antagonist. Tetrahedron Lett., 35: 1157-1160. |
Intracrinology |
1994 |
|
366. Luu-The, V., Sugimoto, Y., Puy, L., Labrie, Y., Lopez Solache, I., Singh, M., Labrie, F. (1994) Characterization, expression and immunohistochemical localization of 5alpha-reductase in human skin. J. Invest. Dermatol., 102: 221-226. |
Intracrinology |
1994 |
|
939. Martel, C., Gagné, D., Couet, J., Labrie, Y., Simard, J., Labrie, F. (1994) Rapid modulation of ovarian 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase gene expression by prolactin and human chorionic gonadotropin in the hypophysectomized rat. Mol. Cell. Endocrinol., 99: 63-71. |
Intracrinology |
1994 |
|
940. Pelletier, G., Luu-The, V., Labrie, F. (1994) Immunocytochemical localization of 5α-reductase in rat brain. Mol. Cell. Neurosci., 5: 394-399. |
Intracrinology |
1994 |
|
465. Pelletier, J.D., Labrie, F., Poirier, D. (1994) N-butyl, N-methyl, 11-3',17'β-dihydroxy-1'3'5'(10') estratrien-16'α-yl)-9-(R/S)bromo undecanamide: synthesis and 17β-HSD inhibiting activity, estrogenic activity and antiestrogenic activity. Steroids, 59: 536-547. |
Intracrinology |
1994 |
|
466. Poirier, D., Auger, S., Mérand, Y., Simard, J., Labrie, F. (1994) Synthesis and antiestrogenic activity of diaryl thioether derivatives. J. Med. Chem., 37: 1115-1125. |
Intracrinology |
1994 |
|
943. Rhéaume, E., Sanchez, R., Simard, J., Chang, Y.T., Wang, J., Pang, S., Labrie, F. (1994) Molecular basis of congenital adrenal hyperplasia in two sibs with classical nonsalt-losing 3β-hydroxysteroid dehydrogenase deficiency. J. Clin. Endocrinol. Metab., 79: 1012-1018. |
Intracrinology |
1994 |
|
944. Sanchez, R., de Launoit, Y., Durocher, F., Bélanger, A., Labrie, F., Simard, J. (1994) Formation and degradation of dihydrotestosterone by recombinant members of the rat 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) family. Mol. Cell. Endocrinol., 103: 29-38. |
Intracrinology |
1994 |
|
945. Sanchez, R., Mebarki, F., Rheaume, E., Laflamme, N., Forest, M.G., Bey-Omard, F., David, M., Morel, Y., Labrie, F., Simard, J. (1994) Functional characterization of the novel L108W and P186L mutations detected in the type II 3β-hydroxysteroid dehydrogenase gene of a male pseudohermaphrodite with congenital adrenal hyperplasia. Hum. Mol. Genet., 3: 1639-1645. |
Intracrinology |
1994 |
|
946. Sanchez, R., Rhéaume, E., Laflamme, N., Rosenfield, R.L., Labrie, F., Simard, J. (1994) Detection and functional characterization of the novel missense mutation Y254D in type II 3β-hydroxysteroid dehydrogenase (3β-HSD) gene of a female patient with nonsalt-losing 3β-HSD deficiency. J. Clin. Endocrinol. Metab., 78: 561-567. |
Intracrinology |
1994 |
|
947. Simard, J., Rhéaume, E., Leblanc, J.F., Wallis, S.C., Joplin, G.F., Gilbey, S., Allanson, J., Mettler, G., Bettendorf, M., Heinrich, U., Labrie, F. (1994) Congenital adrenal hyperplasia caused by a novel homozygous frameshift mutation 273DAA in type II 3β-hydroxysteroid dehydrogenase gene (HSD3β2) in three male patients of Afghan/Pakistani origin. Hum. Mol. Genet., 3: 327-330. |
Intracrinology |
1994 |
|
130. Sugimoto, K., Simard, J., Veilleux, R., Haagensen, D.E., Labrie, F. (1994) Inverse relationships between cell proliferation and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells. J. Steroid Biochem. Mol. Biol., 51: 167-174. |
Intracrinology |
1994 |
|
949. Verreault, H., Dufort, I., Simard, J., Labrie, F., Luu-The, V. (1994) Dinucleotide repeat polymorphisms in the HSD3?2 gene. Hum. Mol. Genet., 3: 384. |
Intracrinology |
1994 |
|
641. Young, J., Couzinet, B., Pholsena, M., Nahoul, K., Labrie, F., Schaison, G. (1994) Plasma 3β-hydroxy-?5-steroids in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J. Clin. Endocrinol. Metab., 78: 299-304. |
Intracrinology |
1994 |
|
951. Zerah, M., Rhéaume, E., Mani, P., Schram, P., Simard, J., Labrie, F., New, M.I. (1994) No evidence of mutations in the genes for type I and type II 3β-hydroxysteroid dehydrogenase (3β-HSD) in nonclassical 3β-HSD deficiency. J. Clin. Endocrinol. Metab., 79: 1811-1817. |
Intracrinology |
1994 |
|
952. Zhu, D.-W., Lee, X., Labrie, F., Lin, S.-X. (1994) Crystal growth of human estrogenic 17β-hydroxysteroid dehydrogenase. Acta Crystallogr., D50: 550-555. |
Intracrinology |
1994 |
|
468. Couture, P., Thériault, C., Simard, J., Labrie, F. (1993) Androgen receptor-mediated stimulation of 17β-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Endocrinology, 132: 179-185. |
Intracrinology |
1993 |
|
954. Cusan, L., Dupont, A., Cossette, M., Labrie, F. (1993) Flutamide in the treatment of female androgenic alopecia. Can. J. Dermatol., 5: 421-427. |
Intracrinology |
1993 |
|
955. de Launoit, Y., Simard, J., Zhao, H.F., Couture, P., Labrie, F. (1993) Structure-function relationships of multiple rat members of the 3β-hydroxysteroid dehydrogenase family (Chapter 14), in: Leung, P.C.K. et Hsueh, A.J.W., eds: Molecular Basis of Reproductive Endocrinology, New York, Springer-Verlag, pp 201-209. |
Intracrinology |
1993 |
|
956. Dupont, E., Labrie, F., Luu-The, V., Pelletier, G. (1993) Ontogeny of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) in rat testis as studied by immunocytochemistry. Anat. Embryol. (Berl.), 187: 583-589. |
Intracrinology |
1993 |
|
957. Juneau, C., Dupont, E., Luu-The, V., Labrie, F., Pelletier, G. (1993) Ontogenesis of 3β-hydroxysteroid dehydrogenase Δ5-Δ4 isomerase in the rat ovary as studied by immunocytochemistry and in situ hybridization. Biol. Reprod., 48: 226-234. |
Intracrinology |
1993 |