Fernand Labrie

Publications

Page 6 of 9, showing 50 records out of 429 total, starting on record 251, ending on 300

Publication Category Year
4. Ma, C., Yoshioka, M., Boivin, A., Belleau, P., Gan, L., Takase, Y., Labrie, F., St-Amand, J. (2008) Prostate specific genes and their regulation by dihydrotestosterone. Prostate, 68: 241-254. Intracrinology 2008
495. Marchetti, B., Labrie, F. (1990) Hormonal regulation of beta-adrenergic receptors in the rat mammary gland during the estrous cycle and lactation: role of sex steroids and prolactin. Endocrinology, 126: 575-581. Intracrinology 1990
939. Martel, C., Gagné, D., Couet, J., Labrie, Y., Simard, J., Labrie, F. (1994) Rapid modulation of ovarian 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase gene expression by prolactin and human chorionic gonadotropin in the hypophysectomized rat. Mol. Cell. Endocrinol., 99: 63-71. Intracrinology 1994
430. Martel, C., Labrie, C., Bélanger, A., Gauthier, S., Mérand, Y., Li, X., Provencher, L., Candas, B., Labrie, F. (1998) Comparison of the effects of the new orally active antiestrogen EM-800 with ICI 182 780 and toremifene on estrogen-sensitive parameters in the ovariectomized mouse. Endocrinology, 139: 2486-2492. Intracrinology 1998
1040. Martel, C., Labrie, C., Couet, J., Dupont, E., Trudel, C., Luu-The, V., Takahashi, M., Pelletier, G., Labrie, F. (1990) Effects of human chorionic gonadotropin (hCG) and prolactin (PRL) on 3beta-hydroxy-5-ene-steroid dehydrogenase/delta5-delta4 isomerase (3beta-HSD) expression and activity in the rat ovary. Mol. Cell. Endocrinol. 72: R7-R13. Intracrinology 1990
1041. Martel, C., Labrie, C., Dupont, E., Couët, J., Trudel, C., Rheaume, E., Simard, J., Luu-The, V., Pelletier, G., Labrie, F. (1990) Regulation of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase expression and activity in the hypophysectomized rat ovary: interactions between the stimulatory effect of human chorionic gonadotropin and the luteolytic effect of prolactin. Endocrinology, 127: 2726-2737. Intracrinology 1990
431. Martel, C., Provencher, L., Li, X., St-Pierre, A., Leblanc, G., Gauthier, S., Mérand, Y., Labrie, F. (1998) Binding characteristics of novel nonsteroidal antiestrogens to the rat uterine estrogen receptors. J. Steroid Biochem. Mol. Biol., 64: 199-205. Intracrinology 1998
983. Martel, C., Rhéaume, E., Takahashi, M., Trudel, C., Couët, J., Luu-The, V., Simard, J., Labrie, F. (1992) Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues. J. Steroid Biochem. Mol. Biol., 41: 597-603. Intracrinology 1992
432. Martel, C., Sourla, A., Pelletier, G., Labrie, C., Fournier, M., Picard, S., Li, S., Stojanovic, M., Labrie, F. (1998) Predominant androgenic component in the stimulatory effect of dehydroepiandrosterone on bone mineral density in the rat. J. Endocrinol., 157: 433-442. Intracrinology 1998
153. Martel, C., Trudel, C., Couet, J., Labrie, C., Bélanger, A., Labrie, F. (1992) Blockade of androgen action by combined treatment with a pure antiandrogen (Flutamide) and a 5α-reductase inhibitor (4-MA), in: Giuliani, L. et Puppo, P., eds: Urology, Bologna, Monduzzi Editore, pp 605-610. Intracrinology 1992
145. Martel, C., Trudel, C., Couet, J., Labrie, C., Bélanger, A., Labrie, F. (1993) Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA. Mol. Cell. Endocrinol., 91: 43-49. Intracrinology 1993
608. Mauriège, P., Langin, D., Montminy, V., Martel, C., Després, J.P., Bélanger, A., Labrie, F., Deshaies, Y. (2000) Effect of a long-term percutaneous adrenal steroid treatment on rat adipose tissue metabolism. Int. J. Obes. Relat. Metab. Disord., 24: S148-S150. Intracrinology 2000
4686. Mellström, D., Vandenput, L., Mallmin, H., Holmberg, AH., Lorentzon, M., Odén, A., Johansson, H., Orwoll, ES., Labrie, F., Karlsson, MK., Ljunggren, Ö., Ohlsson C. (2008) Older men with low serum estradiol and high serum SHBG have an increased risk of fractures. J Bone Miner Res, 23: 1552-1560. Intracrinology 2008
1008. Moorjani, S., Dupont, A., de Lignières, B., Labrie, F., Lupien, P.J. (1990) The effects of oral and nonoral estrogen replacement on plasma low density lipoprotein, in: Christansen, C. et Overgaard, K., eds: Osteoporosis 1990, Denmark, Handelstrykkeriet Press, pp 1942-1946. Intracrinology 1990
1009. Moorjani, S., Dupont, A., Labrie, F., De Lignières, B., Cusan, L., Dupont, P., Mailloux, J., Lupien, P.J. (1991) Changes in plasma lipoprotein and apolipoprotein composition in relation to oral versus percutaneous administration of estrogen alone or in cyclic association with Utrogestan in menopausal women. J. Clin. Endocrinol. Metab., 73: 373-379. Intracrinology 1991
890. Morissette, J., Durocher, F., Leblanc, J.-F., Normand, T., Labrie, F., Simard, J. (1996) Genetic linkage mapping of the human steroid 5alpha-reductase type 2 gene (SRD5alpha2) close to D2S352 on chromosome region 2p22-23. Cytogenet. Cell. Genet., 73: 304-307. Intracrinology 1996
917. Morissette, J., Rhéaume, E., Leblanc, J.-F., Luu-The, V., Labrie, F., Simard, J. (1995) Genetic linkage mapping of HSD3B1 and HSD3B2 encoding human types I and II 3beta-hydroxysteroid dehydrogenase/delta5-delta4-isomerase close to D1S514 and the centromeric D1Z5 locus. Cytogenet Cell Genet, 69: 59-62. Intracrinology 1995
146. Normand, T., Narod, S., Labrie, F., Simard, J. (1993) Detection of polymorphisms in the estradiol 17β-hydroxysteroid dehydrogenase II gene at the human EDH17B2 locus on 17q11-q21. Hum. Mol. Genet., 2: 479-483. Intracrinology 1993
985. Pelletier, G., Dupont, E., Simard, J., Luu-The, V., Bélanger, A., Labrie, F. (1992) Ontogeny and subcellular localization of 3β-hydroxysteroid dehydrogenase (3β-HSD) in the human and rat adrenal, ovary and testis. J. Steroid Biochem. Mol. Biol., 43: 451-467. Intracrinology 1992
52. Pelletier, G., Labrie, C., Labrie, F. (2000) Localization of oestrogen receptor alpha oestrogen receptor beta and androgen receptors in the rat reproductive organs. J. Endocrinol., 165: 359-370. Intracrinology 2000
376. Pelletier, G., Labrie, C., Martel, C., Labrie, F. (2008) Chronic administration of dehydroepiandrosterone (DHEA) to female monkey and rat has no effect on mammary gland histology. J Steroid Biochem Mol Biol, 108: 102-108. Intracrinology 2008
4714. Pelletier, G., Li, S., Luu-The, V., Labrie, F. (2007) Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. J Neuroendocrinol, 19: 426-431 Intracrinology 2007
422. Pelletier, G., Luu-The, V., Charbonneau, A., Labrie, F. (1999) Cellular localization of estrogen receptor beta messenger ribonucleic acid in cynomolgus monkey reproductive organs. Biol. Reprod., 61: 1249-1255. Intracrinology 1999
41. Pelletier, G., Luu-The, V., El Alfy, M., Li, S., Labrie, F. (2001) Immunoelectron microscopic localization of 3beta-hydroxysteroid dehydrogenase and type 5 17beta-hydroxysteroid dehydrogenase in the human prostate and mammary gland. J. Mol. Endocrinol., 26: 11-19. Intracrinology 2001
940. Pelletier, G., Luu-The, V., Labrie, F. (1994) Immunocytochemical localization of 5α-reductase in rat brain. Mol. Cell. Neurosci., 5: 394-399. Intracrinology 1994
918. Pelletier, G., Luu-The, V., Labrie, F. (1995) Immunocytochemical localization of type I 17beta-hydroxysteroid dehydrogenase in the rat brain. Brain Res., 704: 233-239. Intracrinology 1995
740. Pelletier, G., Luu-The, V., Li, S., Bujold, G., Labrie, F. (2007) Localization and glucocorticoid regulation of 11beta-hydroxysteroid dehydrogenase type 1 mRNA in the male mouse forebrain. Neuroscience, 145: 110-115. Intracrinology 2007
764. Pelletier, G., Luu-The, V., Li, S., Ouellet, J., Labrie, F. (2004) Cellular localization of mRNA Expression of Enzymes Involved in the Formation and Inactivation of Hormonal Steroids in the Mouse Prostate. J. Histochem & Cytochem., 52: 1351-1356 Intracrinology 2004
465. Pelletier, J.D., Labrie, F., Poirier, D. (1994) N-butyl, N-methyl, 11-3',17'β-dihydroxy-1'3'5'(10') estratrien-16'α-yl)-9-(R/S)bromo undecanamide: synthesis and 17β-HSD inhibiting activity, estrogenic activity and antiestrogenic activity. Steroids, 59: 536-547. Intracrinology 1994
412. Picard, F., Deshaies, Y., Lalonde, J., Samson, P., Labrie, C., Bélanger, A., Labrie, F., Richard, D. (2000) Effects of the estrogen antagonist EM-652.HCl on energy balance and lipid metabolism in ovariectomized rats. Int. J. Obes. Relat. Metab. Disord., 24: 830-840. Intracrinology 2000
466. Poirier, D., Auger, S., Mérand, Y., Simard, J., Labrie, F. (1994) Synthesis and antiestrogenic activity of diaryl thioether derivatives. J. Med. Chem., 37: 1115-1125. Intracrinology 1994
454. Poirier, D., Mérand, Y., Labrie, C., Labrie, F. (1996) D-Ring alkylamide derivatives of estradiol: Effect on ER-binding affinity and antiestrogenic activity. Bioorg. Med. Chem. Lett., 6: 2537-2542. Intracrinology 1996
496. Poirier, D., Poulin, R., Mérand, Y., Thériault, C., Labrie, F. (1990) High level of esterification of steroids to long-chain fatty acids in ZR-75-1 human breast cancer cells. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 422-424. Intracrinology 1990
865. Poulin, M.-J., Simard, J., Catford, J.-G., Labrie, F., Piché, Y. (1997) Response of symbiotic endomycorrhizal fungi to estrogens and antiestrogens. Mol. Plant. Microbe Interactions, 10: 481-487. Intracrinology 1997
4057. Poulin, R., Baker, D., Poirier, D., Labrie, F. (1990) Multiple actions of synthetics "progestins" on the growth of ZR-75-1 human breast cancer cells: An in vitro model for the simultaneous assay of androgen, progestin, estrogen, and glucocorticoid agonistic and antagonistic activities of steroids. Breast Cancer Res Treat, 17: 197-210. Intracrinology 1990
498. Poulin, R., Poirier, D., Thériault, C., Couture, J., Bélanger, A., Labrie, F. (1990) Wide spectrum of steroids serving as substrates for the formation of lipoidal derivatives in ZR-75-1 human breast cancer cells. J. Steroid Biochem., 35: 237-247. Intracrinology 1990
53. Prostate Cancer Triallist’ Collaborative Group; (2000) Maximum androgen blockade in advanced prostate cancer: an overvierw of the randomised trials. Lancet, 355: 1491-1498. Intracrinology 2000
28. Qiu, W., Zhou, M., Labrie, F., Lin, S.-X. (2004) Crystal structures of the multi-specific 17beta-hydroxysteroid dehydrogenase type 5: Critical androgen regulation in human peripheral tissues. Mol Endocrinol, 18: 1798-1807. Intracrinology 2004
741. Qiu, W., Zhou, M., Mazumdar, M., Azzi, A., Ghanmi, D., Luu-The, V., Labrie, F., Lin, S.-X. (2007) Structure-based inhibitor design for an enzymeTHAT binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol, 282: 8368-79. Intracrinology 2007
987. Rösler, A., Bélanger, A., Labrie, F. (1992) Mechanisms of androgen production in male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency. J. Clin. Endocrinol. Metab., 75: 773-778. Intracrinology 1992
986. Rhéaume, É., Simard, J., Morel, Y., Mebarki, F., Zachmann, M., Forest, M.G., New, M.I., Labrie, F. (1992) Congenital adrenal hyperplasia due to point mutations in the type II 3β-hydroxysteroid dehydrogenase gene. Nat. Genet., 1: 239-245. Intracrinology 1992
1010. Rhéaume, E., Lachance, Y., Zhao, H.F., Breton, N., Dumont, M., de Launoit, Y., Trudel, C., Luu-The, V., Simard, J., Labrie, F. (1991) Structure and expression of a new complementary DNA encoding the almost exclusive 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in human adrenals and gonads. Mol. Endocrinol., 5: 1147-1157. Intracrinology 1991
1011. Rhéaume, E., Leblanc, J.F., Lachance, Y., Labrie, F., Simard, J. (1991) Detection of a frequent BglII polymorphism by polymerase chain reaction and TaqI restriction fragment length polymorphism for 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase at the human HSDbeta3 locus (1p11-p13). Hum. Genet., 87: 753-754. Intracrinology 1991
919. Rhéaume, E., Sanchez, R., Mébarki, F., Gagnon, E., Carel, J.C., Chaussain, J.L., Morel, Y., Labrie, F., Simard, J. (1995) Identification and characterization of the G15D mutation found in a male patient with 3beta-hydroxysteroid dehydrogenase (3beta-HSD) deficiency: alteration of the putative NAD-binding domaine of type II 3beta-HSD. Biochemistry, 34: 2893-2900. Intracrinology 1995
943. Rhéaume, E., Sanchez, R., Simard, J., Chang, Y.T., Wang, J., Pang, S., Labrie, F. (1994) Molecular basis of congenital adrenal hyperplasia in two sibs with classical nonsalt-losing 3β-hydroxysteroid dehydrogenase deficiency. J. Clin. Endocrinol. Metab., 79: 1012-1018. Intracrinology 1994
967. Riley, S.C., Bassett, N.S., Berdusco, E.T., Yang, K., Leystra-Lantz, C., Luu-The, V., Labrie, F., Challis, J.R. (1993) Changes in the abundance of mRNA for type I 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase in the human placenta and fetal membranes during pregnancy and labor. Gynecol. Obstet. Invest., 35: 199-203. Intracrinology 1993
476. Roy, R., Dauvois, S., Labrie, F., Bélanger, A. (1992) Estrogen-stimulated glucuronidation of dihydrotestosterone in MCF-7 human breast cancer cells. J. Steroid Biochem. Mol. Biol., 41: 579-582. Intracrinology 1992
801. Sam, K.-M., Labrie, F., Poirier, D. (2000) N-Butyl-N-methyl-11-(3'-hydroxy-21', 17'-carbolactone-19'-nor-17'alpha-pregna-1',3', 5'(10')-trien-7'alpha-yl)-undecanamide: an inhibitor of type 2 17beta-hydroxysteroid dehydrogenase that does not have oestrogenic or androgenic activity. Eur. J. Med. Chem., 35: 217-225. Intracrinology 2000
4709. Samson, M., Labrie, F., Luu-The, V. (2009) Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line. J Steroid Biochem Mol Biol, 116: 154-159. Intracrinology 2009
4708. Samson, M., Labrie, F., Zouboulis, C.C., Luu-The, V. (2010) Biosynthesis of dihydrotestosterone by a pathway that does not require testosterone as intermediate in the SZ95 sebaceous gland cell line. J Invest Derm. 130:602-604 Intracrinology 2010
<< previous | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 next >>

Biography  |  Publications  |  Scientific Conferences  |  Selected Slide Presentations  |  Awards