Fernand Labrie

Publications

Page 7 of 9, showing 50 records out of 429 total, starting on record 301, ending on 350

Publication Category Year
135. Labrie, F. (1993) Intracrinology: its impact on prostate cancer. Curr. Opin. Urol., 3: 381-387. Intracrinology 1993
136. Labrie, F. (1993) Mechanism of action and pure antiandrogenic properties of Flutamide. Cancer, 72: 3816-3827. Intracrinology 1993
137. Labrie, F. (1993) Non-steroidal antiandrogens, in: Droz, J.P., Cvitkovic, E., Armand, J.P. et Khoury, S., eds: Handook of Chemotherapy in Clinical Oncology, London, Scientific Communication International Ltd., pp 389-391. Intracrinology 1993
139. Labrie, F., Bélanger, A., Dupont, A., Luu-The, V., Simard, J., Labrie, C. (1993) Science behind total androgen blockade: from gene to combination therapy. Clin. Invest. Med., 16: 475-492. Intracrinology 1993
143. Labrie, F., Dupont, A., Simard, J., Luu-The, V., Bélanger, A. (1993) Intracrinology: the basis for the rational design of endocrine therapy at all stages of prostate cancer. Eur. Urol., 24 Suppl. 2: 94-105. Intracrinology 1993
963. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Labrie, C., Dupont, E., Martel, C., Couet, J., Trudel, C., Rhéaume, E., Breton, N., de Launoit, Y., Dumont, M., Zhao, H.F., Lachance, Y. (1993) Structure and control of expression of the 3β-HSD and 17β-HSD genes in classical steroidogenic and peripheral intracrine tissues, in: Leung, P.C.K., Hsueh, A.J.W. et Friesen, H.G., eds: Molecular Basis of Reproductive Endocrinology, New York, Karger, pp 112-143. Intracrinology 1993
470. Li, S., Yan, X., Bélanger, A., Labrie, F. (1993) Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(?)anthracene (DMBA) in the rat. Breast Cancer Res. Treat., 29: 203-217. Intracrinology 1993
145. Martel, C., Trudel, C., Couet, J., Labrie, C., Bélanger, A., Labrie, F. (1993) Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA. Mol. Cell. Endocrinol., 91: 43-49. Intracrinology 1993
146. Normand, T., Narod, S., Labrie, F., Simard, J. (1993) Detection of polymorphisms in the estradiol 17β-hydroxysteroid dehydrogenase II gene at the human EDH17B2 locus on 17q11-q21. Hum. Mol. Genet., 2: 479-483. Intracrinology 1993
967. Riley, S.C., Bassett, N.S., Berdusco, E.T., Yang, K., Leystra-Lantz, C., Luu-The, V., Labrie, F., Challis, J.R. (1993) Changes in the abundance of mRNA for type I 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase in the human placenta and fetal membranes during pregnancy and labor. Gynecol. Obstet. Invest., 35: 199-203. Intracrinology 1993
367. Simard, J., Couet, J., Durocher, F., Labrie, Y., Sanchez, R., Breton, N., Turgeon, C., Labrie, F. (1993) Structure and tissue-specific expression of a novel member of the rat 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) family: the exclusive 3β-HSD gene expressed in the skin. J. Biol. Chem., 268: 19659-19668. Intracrinology 1993
969. Simard, J., Rhéaume, E., Sanchez, R., de Launoit, Y., Laflamme, N., Luu-The, V., van Seters, A.P., Gordon, R.D., Heinrich, U., Moshang, T., New, M.I., Labrie, F. (1993) Molecular basis of congenital adrenal hyperplasia due to 3?-hydroxysteroid dehydrogenase deficiency. Mol. Endocrinol., 7: 716-728. Intracrinology 1993
970. Couët, J., Simard, J., Martel, C., Trudel, C., Labrie, Y., Labrie, F. (1992) Regulation of 3-ketosteroid reductase mRNA levels and 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase activity in rat liver by sex steroids and pituitary hormones. Endocrinology, 131: 3034-3044. Intracrinology 1992
971. de Launoit, Y., Simard, J., Durocher, F., Labrie, F. (1992) Androgenic 17β-hydroxysteroid dehydrogenase activity of expressed rat type I 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase. Endocrinology, 130: 553-555. Intracrinology 1992
972. de Launoit, Y., Zhao, H.F., Bélanger, A., Labrie, F., Simard, J. (1992) Expression of liver specific member of the 3β-hydroxysteroid dehydrogenase family, an isoform possessing an almost exclusive 3-keto steroid reductase activity. J. Biol. Chem., 267: 4513-4517. Intracrinology 1992
973. Dumont, M., Luu-The, V., de Launoit, Y., Labrie, F. (1992) Expression of human 17β-hydroxysteroid dehydrogenase in mammalian cells. J. Steroid Biochem. Mol. Biol., 41: 605-608. Intracrinology 1992
368. Dumont, M., Luu-The, V., Dupont, E., Pelletier, G., Labrie, F. (1992) Characterization, expression and immunohistochemical localization of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase in human skin. J. Invest. Dermatol., 99: 415-421. Intracrinology 1992
975. Dupont, E., Labrie, F., Luu-The, V., Pelletier, G. (1992) Immunocytochemical localization of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) in human ovary. J. Clin. Endocrinol. Metab., 74: 994-998. Intracrinology 1992
473. Labrie, C., Martel, C., Dufour, J.M., Lévesque, C., Mérand, Y., Labrie, F. (1992) Novel compounds inhibit estrogen formation and action. Cancer Res., 52: 610-615. Intracrinology 1992
474. Labrie, F., Simard, J., de Launoit, Y., Poulin, R., Thériault, C., Dumont, M., Dauvois, S., Martel, C., Li, S.; (1992) Androgens and breast cancer. Cancer Detect. Prev., 16: 31-38. Intracrinology 1992
978. Labrie, F., Simard, J., Luu-The, V., Bélanger, A., Pelletier, G. (1992) Structure, function and tissue-specific gene expression of 3β-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase enzymes in classical and peripheral intracrine steroidogenic tissues. J. Steroid Biochem. Mol. Biol., 43: 805-826. Intracrinology 1992
979. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Bélanger, A. (1992) Cloning, expression and regulation of tissue-specific expression of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase in Cellular and Molecular Biology of the Adrenal Cortex, London, John Libbey Eurotext Ltd., pp 89-109. Intracrinology 1992
980. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Bélanger, A., Lachance, Y., Zhao, H.F., Labrie, C., Breton, N., de Launoit, Y., Dumont, M., Dupont, E., Rhéaume, E., Martel, C., Couët, J., Trudel, C. (1992) Structure and tissue-specific expression of 3β-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. J. Steroid Biochem. Mol. Biol., 41: 421-435. Intracrinology 1992
981. Labrie, F., Sugimoto, Y., Luu-The, V., Simard, J., Lachance, Y., Bachvarov, D., Leblanc, G., Durocher, F., Paquet, N. (1992) Structure of human type II 5α-reductase gene. Endocrinology, 131: 1571-1573. Intracrinology 1992
982. Lin, S.-X., Yang, F., Jin, J.-Z., Breton, R., Zhu, D.-W., Luu-The, V., Labrie, F. (1992) Subunit identity of the dimeric 17β-hydroxysteroid dehydrogenase from human placenta. J. Biol. Chem., 267: 16182-16187. Intracrinology 1992
983. Martel, C., Rhéaume, E., Takahashi, M., Trudel, C., Couët, J., Luu-The, V., Simard, J., Labrie, F. (1992) Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues. J. Steroid Biochem. Mol. Biol., 41: 597-603. Intracrinology 1992
153. Martel, C., Trudel, C., Couet, J., Labrie, C., Bélanger, A., Labrie, F. (1992) Blockade of androgen action by combined treatment with a pure antiandrogen (Flutamide) and a 5α-reductase inhibitor (4-MA), in: Giuliani, L. et Puppo, P., eds: Urology, Bologna, Monduzzi Editore, pp 605-610. Intracrinology 1992
985. Pelletier, G., Dupont, E., Simard, J., Luu-The, V., Bélanger, A., Labrie, F. (1992) Ontogeny and subcellular localization of 3β-hydroxysteroid dehydrogenase (3β-HSD) in the human and rat adrenal, ovary and testis. J. Steroid Biochem. Mol. Biol., 43: 451-467. Intracrinology 1992
987. Rösler, A., Bélanger, A., Labrie, F. (1992) Mechanisms of androgen production in male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency. J. Clin. Endocrinol. Metab., 75: 773-778. Intracrinology 1992
986. Rhéaume, É., Simard, J., Morel, Y., Mebarki, F., Zachmann, M., Forest, M.G., New, M.I., Labrie, F. (1992) Congenital adrenal hyperplasia due to point mutations in the type II 3β-hydroxysteroid dehydrogenase gene. Nat. Genet., 1: 239-245. Intracrinology 1992
476. Roy, R., Dauvois, S., Labrie, F., Bélanger, A. (1992) Estrogen-stimulated glucuronidation of dihydrotestosterone in MCF-7 human breast cancer cells. J. Steroid Biochem. Mol. Biol., 41: 579-582. Intracrinology 1992
477. Simard, J., de Launoit, Y., Haagensen, D.E., Labrie, F. (1992) Additive stimulatory action of glucocorticoids and androgens on basal and estrogen-repressed apolipoprotein D messenger RNA levels and secretion in human breast cancer cells. Endocrinology, 130: 1115-1121. Intracrinology 1992
478. Dauvois, S., Geng, C.S., Lévesque, C., Mérand, Y., Labrie, F. (1991) Additive inhibitory effects of an androgen and the antiestrogen EM-170 on estradiol-stimulated growth of human ZR-75-1 breast tumors in athymic mice. Cancer Res., 51: 3131-3135. Intracrinology 1991
479. de Launoit, Y., Dauvois, S., Dufour, M., Simard, J., Labrie, F. (1991) Inhibition of cell cycle kinetics and proliferation by the androgen 5α-dihydrotestosterone and antiestrogen N,n-butyl-N-methyl-11-[16'a-chloro-3',17β-dihydroxy-estra-1',3',5'-(10')triene-7'a-yl] undecanamide in human breast cancer ZR-75-1 cells. Cancer Res., 51: 2797-2802. Intracrinology 1991
156. de Launoit, Y., Veilleux, R., Dufour, M., Simard, J., Labrie, F. (1991) Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells. Cancer Res., 51: 5165-5170. Intracrinology 1991
993. Dupont, A., Dupont, P., Cusan, L., Tremblay, M., Gomez, J.L., Mailloux, J., de Lignières, B., Bélanger, A., Labrie, F. (1991) Efficacy of percutaneous estradiol and oral estrogens as replacement therapy in postmenopausal women, in : Dusitsin, N. et Notelovitz, M., eds: Physiological Hormone Replacement Therapy, New Jersey, USA, The Parthenon Publishing Group, pp 37-50. Intracrinology 1991
994. Dupont, A., Dupont, P., Cusan, L., Tremblay, M., Rioux, J., Cloutier, D., Mailloux, J., De Lignières, B., Gutkowska, J., Boucher, H., Bélanger, A., Moyer, D.L., Moorjani, S., Labrie, F. (1991) Comparative endocrinological and clinical effects of percutaneous estradiol and oral conjugated estrogens as replacement therapy in menopausal women. Maturitas, 13: 297-311. Intracrinology 1991
995. Dupont, E., Labrie, F., Luu-The, V., Pelletier, G. (1991) Localization of 17beta-hydroxysteroid dehydrogenase throughout gestation in the human placenta. J. Histochem. Cytochem., 39: 1403-1407. Intracrinology 1991
996. Dupont, E., Luu-The, V., Labrie, F., Pelletier, G. (1991) Ontogeny of 3beta-hydroxysteroid dehydrogenase/ Delta5-Delta4 isomerase (3beta-HSD) in human testis as studied by immunocytochemistry. J. Androl., 12: 161-164. Intracrinology 1991
997. Dupont, E., Rhéaume, E., Simard, J., Luu-The, V., Labrie, F., Pelletier, G. (1991) Ontogenesis of 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase in the rat adrenal as revealed by immunocytochemistry and in situ hybridization. Endocrinology, 129: 2687-2692. Intracrinology 1991
481. Lévesque, C., Mérand, Y., Dufour, J.M., Labrie, C., Labrie, F. (1991) Synthesis and biological activity of new halo-steroidal antiestrogens. J. Med. Chem., 34: 1624-1630. Intracrinology 1991
998. Labrie, C., Martel, C., Couet, J., Trudel, C., Luu-The, V., Labrie, F. (1991) Pituitary hormone regulation of ovarian 3beta-HSD gene expression and activity in the rat (Chapter 27), in: Gibori, G., ed. Signaling Mechanisms and Gene Expression in the Ovary (Serono Symposia), New York, Springer-Verlag, pp 268-273. Intracrinology 1991
158. Labrie, C., Trudel, C., Li, S., Martel, C., Couët, J., Labrie, F. (1991) Combination of an antiandrogen and a 5a-reductase inhibitor: a further step towards total androgen blockade? Endocrinology, 129: 566-568. Intracrinology 1991
160. Labrie, F. (1991) Intracrinology. Mol. Cell. Endocrinol., 78: C113-C118. Intracrinology 1991
161. Labrie, F., Dupont, A., Cusan, L., Manhès, G., Lacourcière, Y., Monfette, G., Emond, J. (1991) Maximal androgen blockade in prostate cancer: To-Day's Therapy of choice and 5-year clinical experience, in: Vickery, B.H. et Lunenfeld, B., eds: International Symposium on GnRH analogues in Cancer and Human Reproduction, The Netherlands, Kluwer Academic Publishers, pp 79-102. Intracrinology 1991
3990. Labrie, F., Simard, J., Luu-The, V., Bélanger, A., Cusan, L., Dupont, A., Trudel, C., Martel, C., Labrie, C., Zhao, H.F., Dupont, E., Couet, J., Lachance, Y., Dumont, M., de Launoit, Y., Breton, N. (1991) Androgens in post-menopause, in: Rivista di Ostetricia e Ginecologia Pratica e Medicina Perinatale, Palermo, pp 15-24. Intracrinology 1991
1003. Labrie, F., Simard, J., Luu-The, V., Trudel, C., Martel, C., Labrie, C., Zhao, H.F., Rhéaume, E., Couet, J., Breton, N. (1991) Expression of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase (3beta-HSD) and 17beta-hydroxysteroid dehydrogenase (17beta-HSD) in adipose tissue. Int. J. Obstet., 15 Suppl. 2: 91-99. Intracrinology 1991
1004. Lachance, Y., Luu-The, V., Verreault, H., Dumont, M., Rhéaume, E., Leblanc, G., Labrie, F. (1991) Structure of human 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase (3beta-HSD) gene-adrenal and gonadal specificity. DNA Cell Biol., 10: 701-711. Intracrinology 1991
1006. Luu-The, V., Takahashi, M., de Launoit, Y., Dumont, M., Lachance, Y., Labrie, F. (1991) Evidence for distinct dehydrogenase and isomerase sites within a single 3beta-hydroxysteroid dehydrogenase 5-ene-4-ene-isomerase protein. Biochemistry, 30: 8861-8865. Intracrinology 1991
1007. Luu-The, V., Takahashi, M., Labrie, F. (1991) Differential inhibition of dehydrogenase and 5-ene-4-ene isomerase activities of purified 3beta-hydroxysteroid dehydrogenase. Evidence for two distinct sites. J. Steroid Biochem. Molec. Biol., 40: 545-548. Intracrinology 1991
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