Page 7 of 9, showing 50 records out of 429 total, starting on record 301, ending on 350
| Publication |
Category |
Year |
|
944. Sanchez, R., de Launoit, Y., Durocher, F., Bélanger, A., Labrie, F., Simard, J. (1994) Formation and degradation of dihydrotestosterone by recombinant members of the rat 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) family. Mol. Cell. Endocrinol., 103: 29-38. |
Intracrinology |
1994 |
|
945. Sanchez, R., Mebarki, F., Rheaume, E., Laflamme, N., Forest, M.G., Bey-Omard, F., David, M., Morel, Y., Labrie, F., Simard, J. (1994) Functional characterization of the novel L108W and P186L mutations detected in the type II 3β-hydroxysteroid dehydrogenase gene of a male pseudohermaphrodite with congenital adrenal hyperplasia. Hum. Mol. Genet., 3: 1639-1645. |
Intracrinology |
1994 |
|
946. Sanchez, R., Rhéaume, E., Laflamme, N., Rosenfield, R.L., Labrie, F., Simard, J. (1994) Detection and functional characterization of the novel missense mutation Y254D in type II 3β-hydroxysteroid dehydrogenase (3β-HSD) gene of a female patient with nonsalt-losing 3β-HSD deficiency. J. Clin. Endocrinol. Metab., 78: 561-567. |
Intracrinology |
1994 |
|
406. Sauvé, F., McBroom, L.D.B., Gallant, J., Moraitis, A.N., Labrie, F., Giguère, V. (2001) CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant. Mol. Cell. Biol, 21: 343-353. |
Intracrinology |
2001 |
|
367. Simard, J., Couet, J., Durocher, F., Labrie, Y., Sanchez, R., Breton, N., Turgeon, C., Labrie, F. (1993) Structure and tissue-specific expression of a novel member of the rat 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) family: the exclusive 3β-HSD gene expressed in the skin. J. Biol. Chem., 268: 19659-19668. |
Intracrinology |
1993 |
|
499. Simard, J., Dauvois, S., Haagensen, D.E., Lévesque, C., Mérand, Y., Labrie, F. (1990) Regulation of progesterone-binding breast cyst protein GCDFP-24 secretion by estrogens and androgens in human breast cancer cells: a new marker of steroid action in breast cancer. Endocrinology, 126: 3223-3231. |
Intracrinology |
1990 |
|
477. Simard, J., de Launoit, Y., Haagensen, D.E., Labrie, F. (1992) Additive stimulatory action of glucocorticoids and androgens on basal and estrogen-repressed apolipoprotein D messenger RNA levels and secretion in human breast cancer cells. Endocrinology, 130: 1115-1121. |
Intracrinology |
1992 |
|
1013. Simard, J., de Launoit, Y., Labrie, F. (1991) Characterization of the structure-activity relationships of rat types I and II 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase by site-directed mutagenesis and expression in HeLa cells. J. Biol. Chem., 266: 14842-14845. |
Intracrinology |
1991 |
|
29. Simard, J., Dumont, M., Soucy, P., Labrie, F., Tavtigian, S.V. (2004) Prostate Cancer Susceptibility Genes, in: Labrie, F. et Koutsilieris, M., eds: Prostate Cancer: Understanding the pathophysiology and re-designing a therapeutic approach, Athens, Greece, Paschalidis Medical Publications, pp 1-38. |
Intracrinology |
2004 |
|
892. Simard, J., Durocher, F., Mébarki, F., Turgeon, C., Sanchez, R., Labrie, Y., Couet, J., Trudel, C., Rhéaume, E., Morel, Y., Luu-The, V., Labrie, F. (1996) Molecular biology and genetics of the 3beta-hydroxysteroid dehydrogenase/delta5/delta4 isomerase gene family. J. Endocrinol., 150 Suppl.: S189-S207. |
Intracrinology |
1996 |
|
444. Simard, J., Labrie, C., Bélanger, A., Gauthier, S., Singh, S.M., Mérand, Y., Labrie, F. (1997) Characterization of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T-47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro. Int. J. Cancer, 73: 104-112. |
Intracrinology |
1997 |
|
1046. Simard, J., Labrie, C., Mérand, Y., Dufour, J.-M., Lévesque, C., Labrie, F. (1990) Pure antagonistic effect of a new steroidal antiestrogen in rat anterior pituitary cells in culture and in mouse uterus. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 425-427. |
Intracrinology |
1990 |
|
89. Simard, J., Labrie, F. (1997) Recent advances in androgen receptor research: relative potencies of pure antiandrogens and implications for prostate cancer therapy, in: New diagnostic and treatment modalities in prostate cancer, Project in Knowledge, pp 15-23. |
Intracrinology |
1997 |
|
947. Simard, J., Rhéaume, E., Leblanc, J.F., Wallis, S.C., Joplin, G.F., Gilbey, S., Allanson, J., Mettler, G., Bettendorf, M., Heinrich, U., Labrie, F. (1994) Congenital adrenal hyperplasia caused by a novel homozygous frameshift mutation 273DAA in type II 3β-hydroxysteroid dehydrogenase gene (HSD3β2) in three male patients of Afghan/Pakistani origin. Hum. Mol. Genet., 3: 327-330. |
Intracrinology |
1994 |
|
920. Simard, J., Rhéaume, E., Mébarki, F., Sanchez, R., New, M.I., Morel, Y., Labrie, F. (1995) Molecular basis of human 3beta-hydroxysteroid dehydrogenase deficiency. J. Steroid Biochem. Mol. Biol., 53: 127-138. |
Intracrinology |
1995 |
|
893. Simard, J., Rhéaume, E., Sanchez, R., Mebarki, F., Morel, Y., Zerah, M., New, M.I., Labrie, F. (1996) Relation between molecular defect and phenotypic manifestation of human 3beta-hyroxysteroid dehydrogenase deficiency, in: New, M., ed. Frontiers Endocrinol., Serono Symposia Series, pp 39-68. |
Intracrinology |
1996 |
|
921. Simard, J., Sanchez, R., Durocher, F., Rhéaume, E., Turgeon, C., Labrie, Y., Luu-The, V., Mebarki, F., Morel, Y., de Launoit, Y., Labrie, F. (1995) Structure-function relationships and molecular genetics of the 3beta-hydroxysteroid dehydrogenase gene family. J. Steroid Biochem. Mol. Biol., 55: 489-505. |
Intracrinology |
1995 |
|
445. Simard, J., Sanchez, R., Poirier, D., Gauthier, S., Singh, S.M., Mérand, Y., Bélanger, A., Labrie, C., Labrie, F. (1997) Blockade of the stimulatory effect of estrogens, OH-Tamoxifen, OH-Toremifene, Droloxifene and Raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human endometrial adenocarcinoma Ishikawa cells. Cancer Res., 57: 3494-3497. |
Intracrinology |
1997 |
|
90. Simard, J., Singh, S.M., Labrie, F. (1997) Comparison of in vitro effects of the pure antiandrogens OH-Flutamide, Casodex and Nilutamide on androgen-sensitive parameters. Urology, 49: 580-589. |
Intracrinology |
1997 |
|
1014. Simard, J., Zhao, H.F., Labrie, C., Trudel, C., Rhéaume, E., Dupont, E., Breton, N., Luu-The, V., Pelletier, G., Labrie, F. (1991) Molecular cloning of rat 3beta-HSD: structure of two types of cDNAs and differential expression of corresponding mRNAs in the ovary (Chapter 28), in: Gibori, G., ed. Signaling Mechanisms and Gene Expression in the Ovary (Serono Symposia), New York, NY, USA, Springer-Verlag, pp 274-279. |
Intracrinology |
1991 |
|
802. Singh, S.M., Gauthier, S., Labrie, F. (2000) Androgen receptor antagonists (antiandrogens): structure-activity relationships. Curr. Med. Chem., 7: 211-247. |
Intracrinology |
2000 |
|
384. Song, D., Liu, G., Luu-The, V., Zhao, D., Wang, L., Zhang, H., Xueling, G., Li, S., Desy, L., Labrie, F., Pelletier, G. (2006) Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study. J Steroid Biochem Mol Biol, 101: 136-44. |
Intracrinology |
2006 |
|
447. Sourla, A., Luo, S., Labrie, C., Bélanger, A., Labrie, F. (1997) Morphological changes induced by six-month treatment of intact and ovariectomized mice with tamoxifen and the pure antiestrogen EM-800. Endocrinology, 138: 5605-5617. |
Intracrinology |
1997 |
|
433. Sourla, A., Martel, C., Labrie, C., Labrie, F. (1998) Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland. Endocrinology, 139: 753-764. |
Intracrinology |
1998 |
|
360. Sourla, A., Richard, V., Labrie, F., Labrie, C. (2000) Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin. J. Endocrinol., 166: 455-462. |
Intracrinology |
2000 |
|
4683. Spitz, I.M., Chertin, B., Fridmans, A., Farkas, A., Bélanger, A., Hartman, H., Labrie, F. (2009). Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists. Prostate Cancer Prostatic Dis, 12: 100-103. |
Intracrinology |
2009 |
|
4713. Stener-Victorin, E., Holm, G., Labrie, F., Nilsson, L., Janson, P.O., Ohlsson C. (2010) Are there any sensitive and specific sex steroid markers for polycystic ovary syndrome? J Clin Endocrinol Metab, 95: 810-819. |
Intracrinology |
2010 |
|
130. Sugimoto, K., Simard, J., Veilleux, R., Haagensen, D.E., Labrie, F. (1994) Inverse relationships between cell proliferation and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells. J. Steroid Biochem. Mol. Biol., 51: 167-174. |
Intracrinology |
1994 |
|
364. Sugimoto, Y., Lopez-Solache, I., Labrie, F., Luu-The, V. (1995) Cations inhibit specifically Type I 5alpha-reductase found in human skin. J. Invest. Dermatol., 104: 775-778. |
Intracrinology |
1995 |
|
120. Sun, S., Narod, S., Aprikian, A., Ghadirian, P., Labrie, F. (1995) Androgen receptor and familial prostate cancer. Nature Medicine, 1: 848-849. |
Intracrinology |
1995 |
|
10. Suzuki, K., Nishiyama, T., Hara, N., Yamana, K., Takahashi, K., Labrie, F. (2007) Importance of the intracrine metabolism of adrenal androgens in androgen-dependent prostate cancer. Prostate Cancer Prostatic Dis., 10: 301-6. |
Intracrinology |
2007 |
|
564. Swanson, C., Lorentzon, M., Vandenput, L., Labrie, F., Rane, A., Jakobsson, J., Chouinard, S., Bélanger, A., Ohlsson, C. (2007) Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y). J Clin Endocrinol Metab, 92: 3697-704. |
Intracrinology |
2007 |
|
11. Swanson, C., Mellström, D., Lorentzon, M., Vanderput, L., Jakobsson, J., Rane, A., Karlsson, M., Ljunggren, O., Smith, U., Eriksson, A.E., Bélanger, A., Labrie, F., Ohlsson, C. (2007) The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men. J Clin Endocrinol Metab, 92: 4878-4882. |
Intracrinology |
2007 |
|
1047. Takahashi, M., Luu-The, V., Labrie, F. (1990) Inhibitory effect of synthetic progestins, 4-MA and cyanoketone on human placental 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase activity. J. Steroid Biochem. Mol. Biol., 37: 231-236. |
Intracrinology |
1990 |
|
1048. Takahashi, M., Luu-The, V., Labrie, F. (1990) Purified microsomal and mitochondrial 3beta-hydroxysteroid dehydrogenase/delta4-delta5 isomerase from human placenta. Characterization of substrate and inhibitor specificity. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 383-385. |
Intracrinology |
1990 |
|
18. Takase, Y., Lévesque, M.H., Luu-The, V., El-Alfy, M., Labrie, F., Pelletier, G. (2006) Expression of enzymes involved in estrogen metabolism in human prostate. J.Histochem Cytochem., 54: 911-21. |
Intracrinology |
2006 |
|
12. Takase, Y., Luu-The, V., Poisson-Paré, D., Labrie, F., Pelletier, G. (2007) Expression of sulfotransferase 1E1 in human prostate as studied by in situ hybridization and immunocytochemistry. Prostate, 67: 405-409. |
Intracrinology |
2007 |
|
385. Tchédam Ngatcha, B., Luu-The, V., Labrie, F., Poirier, D. (2005) Androsterone 3beta-Ether-3beta-Substituted and Androsterone 3beta-Substituted derivatives as inhibitors of type 3 17beta-hydroxysteroid dehydrogenase: chemical synthesis and structure-activity relationship. J. Med. Chem., 48: 5257-5268. |
Intracrinology |
2005 |
|
631. Tchernof, A., Labrie, F., Bélanger, A., Després, J.P. (1996) Obesity and metabolic complications: contribution of DHEA and other steroid hormones. J. Endocrinol, 150: S155-S164. |
Intracrinology |
1996 |
|
500. Thériault, C., Poulin, R., Tremblay, S., Poirier, D., Labrie, F. (1990) Hormonal regulation of estradiol 17beta-hydroxysteroid dehydrogenase activity in the ZR-75-1 human breast cancer cell line. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F. eds. Steroid Formation, Degradation and Action in Peripheral, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 419-421. |
Intracrinology |
1990 |
|
4704. Tivesten, A., Vandenput, L., Labrie, F., Karlsson, M.K., Ljunggren, O., Mellström, D., Ohlsson, C. (2009) Low serum testosterone and estradiol predict mortality in elderly men. J Clin Endocrinol Metab, 94: 2482-2488. |
Intracrinology |
2009 |
|
1050. Tong, Y., Zhao, H., Labrie, F., Pelletier, G. (1990) Effects of estrogens on the ultrastructural characteristics of female rat prolactin cells as evaluated by in situ hybridization in combination with immunogold staining technique. Neuroendocrinology, 52: 309-315. |
Intracrinology |
1990 |
|
1051. Tong, Y., Zhao, H., Labrie, F., Pelletier, G. (1990) Regulation of proopiomelanocortin messenger ribonucleic acid content by sex steroids in the arcuate nucleus of the female rat brain. Neurosci. Lett. 112: 104-108. |
Intracrinology |
1990 |
|
434. Tremblay, A., Tremblay, G.B., Labrie, C., Labrie, F., Giguère, V. (1998) EM-800, a novel antiestrogen, acts as a pure antagonist of the transcriptional functions of estrogen receptors α and beta. Endocrinology, 139: 111-118. |
Intracrinology |
1998 |
|
448. Tremblay, G.B., Tremblay, A., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Labrie, F., Giguère, V. (1997) Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta. Mol. Endocrinol., 11: 353-365. |
Intracrinology |
1997 |
|
435. Tremblay, G.B., Tremblay, A., Labrie, F., Giguère, V. (1998) Ligand-independent activation of the estrogen receptors α and beta by mutations of a conserved tyrosine can be abolished by antiestrogens. Cancer Res., 58: 877-881. |
Intracrinology |
1998 |
|
424. Tremblay, G.B., Tremblay, A., Labrie, F., Giguère, V. (1999) Dominant activity of activation function-1 (AF-1) and differential stoichiometric requirements for AF-1 and -2 in the estrogen receptor α⁄β heterodimeric complex. Mol. Cell. Biol., 19: 1919-1927. |
Intracrinology |
1999 |
|
827. Tremblay, M.R., Luu-The, V., Leblanc, G., Noël, P., Breton, E., Labrie, F., Poirier, D. (1999) Spironolactone-related inhibitors of type II 17Beta-hydroxysteroid dehydrogenase: Chemical synthesis, receptor binding affinities, and proliferative/antiproliferative activities. Bioorg. Med. Chem., 7: 1013-1023. |
Intracrinology |
1999 |
|
1015. Trudel, C., Couet, J., Martel, C., Labrie, C., Labrie, F. (1991) Regulation of adrenal 3beta-hydroxysteroid dehydrogenase/delta5-delta4-isomerase expression and activity by adrenocorticotropin and corticosterone in the rat. Endocrinology, 129: 2077-2084. |
Intracrinology |
1991 |
|
106. Vaillancourt, L., Têtu, B., Fradet, Y., Dupont, A., Gomez, J., Cusan, L., Suburu, R.E., Diamond, P., Candas, B., Labrie, F. (1996). Effect of neoadjuvant endocrine therapy (combined androgen blockade) on normal prostate and prostatic carcinoma: a randomized study. Am. J. Surg. Pathol., 20: 86-93. |
Intracrinology |
1996 |