Fernand Labrie

Publications

Page 1 of 25, showing 50 records out of 1234 total, starting on record 1, ending on 50

Publication Category Year
1234. Lee, D., Ulubaev, A., Tajar, A., Pye, S., Pendleton, N., Purandare, N., O’Neill, T., O’Connor, D., Labrie, F., Platt, H., Payne, D., Bartfai, G., Boonen, S., Casanueva, F., Finn, J., Forti, G., Giwercman, A., Han, T., Huhtaniemi, I, Kula, K, Lean, M., Punab, M., Silman, A., Vanderschueren, D., Wu, F. (2010) Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study (EMAS). Eur J Endocrinol. 162: 1155-1164. All publications 2010
1233. Wu, FCW., Tajar, A., T., Beynon, JM., Pye, SR., Silman, AJ., Finn, JD., O’Neill, TW., Bartfai, G., Casanueva, FF., Forti, G., Giwercman, A., Han, TS., Kula, K, Lean, MEJ., Vanderschueren, D., Labrie, F., Huhtaniemi, IT.,  (2010) Identification of late-onset hypogonadism in middle-aged and elderly men. New England Journal of Medicine. 363:123-135. All publications 2010
1232. Labrie, F. (2010) DHEA, important source of sex steroid in men and even more in women. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 4, Vol. 182 97-148. All publications 2010
1231. Labrie, F. (2010) Hormonal therapy of prostate cancer. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Pathological Situations and Diseases, Progress in Brain Research. Elsevier. Chapter 14, Vol. 182 321-341. All publications 2010
1230. Berger, L., E-Alfy, M., Martel, C., Labrie, F. (2010) Effect of long-term topical application of dehydroepiandrosterone (DHEA) and oral estrogens on morphology, cell proliferation, procollagen A1 and androgen receptor levels in rat skin. HMBCI. In press. All publications 2010
1229. Huhtaniemi, I.T., Pye, S.R., Holliday, K.L., Thomson, W., O’Neill, T.W., Platt, H., Payne, D., John, S.L., Jiang, M., Bartfai, G., Boonen, S., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A., Han, T.S., Kula, K, ;Lean, M.E.J., Pendleton, N., Punab, M., Silman, A.J., Vanderschueren, D., Wu, F.C.W. and the EMAS study group (2010) Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men. J Clin Endocrinol Metab. 95:1898-1908. All publications 2010
1228. Labrie, F., Archer, D., Bouchard, C., Fortier, M., Cusan, L., Gomez, JL., Girard, G., Baron, M., Ayotte, N., Moreau, M., Dubé, R., Côté, I, Labrie, C., Lavoie, L., Berger, L., Martel, C., Balser, J. (2010) High internal consistency and efficacy of intravaginal DHEA for vaginal atrophy. Gynecological Endocrinology, 26: 524-532. All publications 2010
1227. Labrie, F., Martel, C., Balser, J. (2010) Wide distribution of the serum levels of DHEA and sex steroids in postmenopausal women – role of the ovary? Menopause. In press. All publications 2010
1226. Luu-The V, Labrie F. (2010) The intracrine sex steroid biosynthesis pathways. In: Martini L, Chrousos GP, Labrie F, Pacak K, Pfaff De, eds. Neuroendocrinology, Pathological Situations and Diseases,  Progress in Brain Research. Elsevier. Vol 181 (Chapter 10): 2010:177-192. All publications 2010
1225. Ohlsson, C., Labrie, F., Barrett-Connor, E., Karlsson, M.K., Ljunggren, Ö., Vandenput, L., Mellström, D., Tivesten, Å. (2010) Low serum levels of dehydroepiandrosterone Predict all-cause and cardiovascular mortality in elderly Swedish men.JCEM. In press. All publications 2010
1224. Orwoll, E.S., Nielson, C.M., Labrie, F., Barrett-Connor, E., Cauley, J.A., Cummings, S.R., Ensrud, K., Karlsson, M., Lau, E., Leung, P.C., Lunggren, Ö., Mellström, D., Patrick, A.L., Stefanick, M.L., Nakamura, K., Yoshimura, N., Zmuda, J., Vandenput, L, Ohlsson, C. (2010) Geographical and racial variation in serum sex steroid levels in older men. J Clin Endocrinol Metab. In press. All publications 2010
1223. Poisson-Paré, D., Song, D., Luu-The, V., Han, B., Li, S., Liu, G., Labrie, F., Pelletier, G. (2009) Expression of estrogen sulfotransferase 1E1 and steroid sulfatase in breast cancer: A immunohistochemical study. Breast Cancer: basic and Clinical 3: 9-21. All publications 2009
1222. Tajar, A., Forti, G., O’Neill, T.W., Lee, D.M., Silman A.J., Finn, J.D., Bartfai, G., Boonen, S., Casaneuva, F.F., Giwercman, A. Han, T.S., Kula, K., Labrie, F., Lean, M.E.J., Pendleton, N., Punab, M., Vanderschueren, D., Huhtaniemi, I.T., Wu, F.C.W., and the EMAS Group (2010) Characteristics of secondary, primary and compensated hypogonadism in ageing men: Evidence from the European male ageing study (EMAS). J Clin Endocrinol Metab. 95:1810-1818. All publications 2010
1221. Vanderschueren, D., Pye, S.R., Venken, K., Borghs, H., Gaytant, J., Huhtaniemi, I.T., Adams, J.E., Ward, K.A., Bartfai, G., Casanueva, F.F., Finn, J.D., Forti, G., Giwercman, A, Han, T.S., Kula, K., Labrie, F., Lean, M.E., Pendleton, N., Punab, M., Silman, A.J., Wu, F.C, O’Neill, T.W, Boonen, S., The EMAS Study Group (2010) Gonadal sex steroid status and bone health in middle-aged and elderly European men. Osteoporosis Int. 21:1331-1339 All publications 2010
1220. Li, S., Han, B., Liu, G., Li, S., Ouellet, J., Labrie, F., Pelletier, G. (2010) Immunocytochemical localization of sex steroid hormone receptors in normal human mammary gland. J Histochem Cytochem. 58:509-15. All publications 2010
1219. Akaza, H., Hirao, Y., Labrie, F., Soloway, M.S. (2003) Future prospects for primary hormone therapy in localized and locally advanced prostate cancer. Hinyokika kiyo, Acta Urologica Japonica, 49: 771-7. All publications 2003
1218. Akaza, H., Labrie, F., Namiki, M. (2007) [A way of thinking of a MAB therapy for local/locally advanced prostate cancer: the theory and recent evaluation]. Gan To Kagaku Ryoho. Jpn J Cancer Chemotherapy, 34: 657-669. All publications 2007
1217. Azzi, L., El-Alfy, M., Labrie, F. (2006) Gender differences and effects of sex steroids and dehydroepiandrosterone on androgen and oestrogen alpha receptors in mouse sebaceous glands. Br J Dermatol., 154: 21-7. All publications 2006
1216. Azzi, L., El-Alfy, M., Martel, C., Labrie, F. (2005) Gender differences in mouse skin morphology and specific effects of sex steroids and dehydroepiandrosterone. J Invest Dermatol, 124: 22-7. All publications 2005
1215. Bélanger, A., Pelletier, G., Labrie, F., Barbier, O., Chouinard, S. (2003) Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans. Trends Endoclinol Metab, 14(10): 473-9. All publications 2003
1214. Barbier, O., Albert, C., Martineau, I., Vallée, M., High, K., Labrie, F., Hum, D.W., Labrie, C., Bélanger, A. (2003) Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068) by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes. Mol Pharmacol, 59: 636-45. All publications 2001
1213. Basson, R., Brotto, L.A., Petkau, J., Labrie, F. (2010) Role of androgens in women's sexual dysfunction. Menopause. in press All publications 2010
1212. Bellemare, V., Labrie, F., Luu-The, V. (2006) Isolation and characterization of a cDNA encoding mouse 3β-hydroxysteroid dehydrogenase an androgen-inactivating enzyme selectively expressed in female tissues. J Steroid Biochem Mol Biol, 98: 18-24. All publications 2006
1211. Berger, L., El-Alfy, M., Labrie, F. (2008) Effects of intravaginal dehydroepiandrosterone on vaginal histomorphology, sex steroid receptor expression and cell proliferation in the rat. J Steroid Biochem Mol Biol, 109: 67-80. All publications 2008
1210. Berger, L., El-Alfy, M., Martel, C., Labrie, F. (2005) Effects of DHEA, Premarin and Acolbifene on histomorphology and sex steroid receptors of the rat vagina. J Steroid Biochem Mol Biol, 96: 201-15. All publications 2005
1209. Bernardi, F., Stomati, M., Luisi, S., Pieri, M., Labrie, F., Geneazzani, A.R. (2002) Effects of the new generation selective estrogen receptor modulator EM-652 and oral administration of estradiol valerate on circulating, brain, and adrenal β-endorphin and allopregnanolone levels in intact fertile and ovariectomized rats. Fertility and Sterility, 77: 1018-1027. All publications 2002
1208. Boivin, R.P., Luu-The, V., Lachance, R., Labrie, F., Poirier, D. (2000) Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase. J. Med. Chem., 43: 4465-4478. All publications 2000
1207. Boivin, R.P., Poirier, D., Labrie, F. (1999) 17alpha-alkan (or alkyn) amide derivatives of estradiol as inhibitors of steroid-sulfatase activity. Steroids, 64: 825-833. All publications 1999
1206. Bolduc, C., Larose, M., Yoshioka, M., Ye, P., Belleau, P., Labrie, C., Morissette, J., Raymond, V., Labrie, F., St-Amand, J. (2004) Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression. J Mol Endocrinol, 33: 429-444. All publications 2004
1205. Brawer, M.K., Crawford, E.D., Labrie, F., Mendoza-Valdz, A., Miller, P.D., Petrylak, D.P. (2001) Androgen deprivation and other treatments for advanced prostate cancer. Reviews in Urology, 3: S59-S68. All publications 2001
1204. Calvo, E., Luu-The, V., Morissette, J., Martel, C., Labrie, C., Bernard, B., Bernerd, F., Deloche, C., Chaussade, V., Leclaire, J., Labrie, F., (2008) Pangenomic Changes Induced by DHEA in the Skin of Postmenopausal Women. J Steroid Biochem Mol Biol, 112: 186-193 All publications 2008
1203. Candas, B., Cusan, L., Gomez, J.-L., Diamond, P., Suburu, R.E., Lévesque, J., Brousseau, G., Bélanger, A., Labrie, F. (2000) Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer. Prostate, 45: 19-35. All publications 2000
1202. Candas, B., Labrie, F., Gomez, J.L., Cusan, L., Chevrette, E., Levesque, J., Brousseau, G. (2006) Relationship among initial serum prostate specific antigen, prostate specific antigen progression and prostate cancer detection at repeat screening visits. J Urol, 175: 510-517. All publications 2006
1201. Cantin, L., Faucher, F., Couture, J.F., de Jésus, K.P., Legrand, P., Ciobanu, L., Fréchette, Y., Labrecque, R., Singh, S.M., Labrie, F., Breton, R. (2007) Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally-designed steroidal ligand bearing a bulky chain directed toward helix 12. J Biol Chem, 282: 30910-9. All publications 2007
1200. Chouinard, S., Tessier, M., Vernouillet, G., Gauthier, S., Labrie, F., Barbier, O., Bélanger, A. (2006) Inactivation of the pure antiestrogen Fulvestrant and other synthetic estrogen molecules by UGT1A enzymes expressed in the breast tissue. Mol Pharmacol, 69: 908-20. All publications 2006
1199. Ciobanu, L.C., Boivin, R.P., Luu-The, V., Labrie, F., Poirier, D. (1999) Potent inhibition of steroid sulfatase activity by 3-Ο-sulfamate-17α-benzyl (or 4'-tert-butylbenzyl)-estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and C17α of estradiol. J. Med. Chem., 42: 2280-2286. All publications 1999
1198. Ciobanu, L.C., Luu-The, V., Martel, C., Labrie, F., Poirier, D. (2003) Inhibition of estrone sulfate-induced uterine growth by potent nonestrogenic steroidal inhibitors of steroid sulfatase. Cancer Res., 63: 6442-6446. All publications 2003
1197. Compère, V., Ouellet, J., Luu-The, V., Dureuil, B., Tonon, M.C., Vaudry, H., Labrie, F., Pelletier, G. (2006) Role of androgens and glucocorticoids in the regulation of diazepam-binding inhibitor mRNA levels in male mouse hypothalamus. Brain Res. 1119: 50-7. All publications 2006
1196. Couillard, S., Gutman, M., Labrie, C., Bélanger, A., Candas, B., Labrie, F. (1998) Comparison of the effects of the antiestrogens EM-800 and Tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice. Cancer Res., 58: 60-64. All publications 1998
1195. Couillard, S., Gutman, M., Labrie, F., Candas, B., Labrie, C. (1999) Effect of the combined treatment with the pure antiestrogen EM-800 and radiotherapy on the growth of human ZR-75-1 breast cancer xenografts in nude mice. Cancer Res., 59: 4857-4863. All publications 1999
1194. Couillard, S., Labrie, C., Bélanger, A., Candas, B., Pouliot, F., Labrie, F. (1998) Effect of dehydroepiandrosterone and the antiestrogen EM-800 on growth of human ZR-75-1 breast cancer xenografts. J. Natl. Cancer Inst., 90: 772-778. All publications 1998
1193. Couillard, S., Labrie, C., Gauthier, S., Mérand, Y., Singh, S.M., Candas, B., Labrie, F. (2000) Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice. Int. J. Cancer, 85: 424-429. All publications 2000
1192. Couture, J.-F., Cantin, L., Legrand, P., Luu-The, V., Labrie, F., Breton, R. (2002) Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates. Acta Cryst. D. Biol. Crystallogr., D58: 135-139. All publications 2002
1191. Couture, J.-F., Legrand, P., Cantin, L., Luu-The, V., Labrie, F., Breton, R, (2003) Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids. J.Mol. Biol., 331: 593-604. All publications 2003
1190. Couture, J.-F., Legrand, P., Cantin, L., Luu-The, V., Labrie, F., Breton, R. (2004) Loop relaxation, a mechanism which explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily. J.Mol. Biol., 339: 89-102. All publications 2004
1189. Couture, J.-F., Pereira de Jésus-Trans, K., Roy, A.-M., Cantin, L., Côté, P.-L., Legrand, P., Luu-The, V., Labrie, F., Breton, R. (2005) Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen. Protein Science, 14: 1485-1497. All publications 2005
1188. Crawford, E.D., Miller, G., Labrie, F., Hirano, D., Batuello, J., Globe, M. (2001) Prostate cancer pathology, screening and epidemiology. Reviews in Urology, 3: S2-S10. All publications 2001
1187. Diamond, P., Cusan, L., Gomez, J.L., Bélanger, A., Labrie, F. (1996) Metabolic effects of 12-month percutaneous DHEA replacement therapy in postmenopausal women. J. Endocrinol., 150 Suppl.: S43-S50. All publications 1996
1186. Dimitrakakis, C., Zhou, J., Wang, J., Belanger, A., Labrie, F., Cheng, C., Powell, D., Bondy, C. (2003) A physiologic role for testosterone in limiting estrogenic stimulation of the breast. Menopause, 10: 292-298. All publications 2003
1185. Dinel, S., Bolduc, C., Belleau, P., Boivin, A., Yoshioka, M., Calvo, E., Piedboeuf, B., Snyder, E.E., Labrie, F., St-Amand, J. (2005) Reproducibility bioinformatic analaysis and power of SAGE method to evaluate changes in transcriptome. Nucleic Acids Res., 33:e26: 1-8. All publications 2005
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