Fernand Labrie

Publications

Page 3 of 26, showing 50 records out of 1263 total, starting on record 101, ending on 150

Publication Category Year
407. Couillard, S., Labrie, C., Gauthier, S., Mérand, Y., Singh, S.M., Candas, B., Labrie, F. (2000) Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice. Int. J. Cancer, 85: 424-429. All publications 2000
3619. Couture, J.-F., Cantin, L., Legrand, P., Luu-The, V., Labrie, F., Breton, R. (2002) Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates. Acta Cryst. D. Biol. Crystallogr., D58: 135-139. All publications 2002
3598. Couture, J.-F., Legrand, P., Cantin, L., Luu-The, V., Labrie, F., Breton, R, (2003) Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids. J.Mol. Biol., 331: 593-604. All publications 2003
3571. Couture, J.-F., Legrand, P., Cantin, L., Luu-The, V., Labrie, F., Breton, R. (2004) Loop relaxation, a mechanism which explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily. J.Mol. Biol., 339: 89-102. All publications 2004
3549. Couture, J.-F., Pereira de Jésus-Trans, K., Roy, A.-M., Cantin, L., Côté, P.-L., Legrand, P., Luu-The, V., Labrie, F., Breton, R. (2005) Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen. Protein Science, 14: 1485-1497. All publications 2005
468. Couture, P., Thériault, C., Simard, J., Labrie, F. (1993) Androgen receptor-mediated stimulation of 17β-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Endocrinology, 132: 179-185. All publications 1993
36. Crawford, E.D., Miller, G., Labrie, F., Hirano, D., Batuello, J., Globe, M. (2001) Prostate cancer pathology, screening and epidemiology. Reviews in Urology, 3: S2-S10. All publications 2001
1023. Cusan, L., Dupont, A., Bélanger, A., Tremblay, R.R., Manhès, G., Labrie, F. (1990) Treatment of hirsutism with the pure antiandrogen flutamide. J. Am. Acad. Dermatol. 23: 462-469. All publications 1990
954. Cusan, L., Dupont, A., Cossette, M., Labrie, F. (1993) Flutamide in the treatment of female androgenic alopecia. Can. J. Dermatol., 5: 421-427. All publications 1993
637. Cusan, L., Dupont, A., Gomez, J.L., Tremblay, R.R., Labrie, F. (1994) Comparison of Flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial. Fertil. Steril., 61: 281-287. All publications 1994
94. Cusan, L., Gomez, J.L., Diamond, P., Candas, B., Labrie, F. (1996) Combined androgen blockade with GnRH analogues and Flutamide at all stages of prostate cancer (Chapter 15), in: Filicori, M. et Flamigni, C., eds: Treatment with GnRH Analogs: Controversies and Prospectives, New-York, The Parthenon Publishing Group, pp 125-137. All publications 1996
122. Cusan, L., Gomez, J.L., Dupont, A., Diamond, P., Lemay, M., Moore, S., Labrie, F. (1994) Metastatic prostate cancer pulmonary nodules: beneficial effects of combination therapy and subsequent withdrawal of flutamide. Prostate, 24: 257-261. All publications 1994
632. Dalla Valle, L., Couet, J., Labrie, Y., Simard, J., Belvedere, P., Simontacchi, C., Labrie, F., Colombo, L. (1995) Occurrence of cytochrome 450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract. Mol. Cell. Endocrinol., 111: 83-92. All publications 1995
478. Dauvois, S., Geng, C.S., Lévesque, C., Mérand, Y., Labrie, F. (1991) Additive inhibitory effects of an androgen and the antiestrogen EM-170 on estradiol-stimulated growth of human ZR-75-1 breast tumors in athymic mice. Cancer Res., 51: 3131-3135. All publications 1991
501. Dauvois, S., Labrie, F. (1989) Androstenedione and androst-5-ene-3beta, 17beta-diol stimulate DMBA-induced rat mammary tumors-role of aromatase. Breast Cancer Res. Treat., 13: 61-69. All publications 1989
487. Dauvois, S., Labrie, F. (1990) Effect of adrenal estrogens on the growth of dimethylbenz(a)antracene-induced mammary carcinoma in the rat. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F., eds. Steroid Formation, Degradation and Action in Peripheral Tissues, Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 416-418. All publications 1990
488. Dauvois, S., Li, S., Labrie, F. (1990) Antagonism between androgens and estrogens on the growth of mammary carcinoma in vivo. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F., eds. Steroid Formation, Degradation and Action in Normal, Neoplasic and Peripheral Tissues. Ann. New York Acad. Sci. pp 413-415. All publications 1990
502. Dauvois, S., Li, S., Martel, C., Labrie, F. (1989) Inhibitory effect of androgens on DMBA-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 14: 299-306. All publications 1989
489. Dauvois, S., Simard, J., Dumont, M., Haagensen, D.E., Labrie, F. (1990) Opposite effects of estrogen and the progestin R5020 on cell proliferation and GCDFP-15 expression in ZR-75-1 human breast cancer cells. Mol. Cell. Endocrinol. 73: 171-178. All publications 1990
503. Dauvois, S., Spinola, P.G., Labrie, F. (1989) Additive inhibitory effects of bromocriptine (CB-154) and medroxyprogesterone acetate (MPA) on dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in the rat. Eur. J. Cancer Clin. Oncol., 25: 891-897. All publications 1989
479. de Launoit, Y., Dauvois, S., Dufour, M., Simard, J., Labrie, F. (1991) Inhibition of cell cycle kinetics and proliferation by the androgen 5α-dihydrotestosterone and antiestrogen N,n-butyl-N-methyl-11-[16'a-chloro-3',17β-dihydroxy-estra-1',3',5'-(10')triene-7'a-yl] undecanamide in human breast cancer ZR-75-1 cells. Cancer Res., 51: 2797-2802. All publications 1991
971. de Launoit, Y., Simard, J., Durocher, F., Labrie, F. (1992) Androgenic 17β-hydroxysteroid dehydrogenase activity of expressed rat type I 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase. Endocrinology, 130: 553-555. All publications 1992
955. de Launoit, Y., Simard, J., Zhao, H.F., Couture, P., Labrie, F. (1993) Structure-function relationships of multiple rat members of the 3β-hydroxysteroid dehydrogenase family (Chapter 14), in: Leung, P.C.K. et Hsueh, A.J.W., eds: Molecular Basis of Reproductive Endocrinology, New York, Springer-Verlag, pp 201-209. All publications 1993
156. de Launoit, Y., Veilleux, R., Dufour, M., Simard, J., Labrie, F. (1991) Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells. Cancer Res., 51: 5165-5170. All publications 1991
972. de Launoit, Y., Zhao, H.F., Bélanger, A., Labrie, F., Simard, J. (1992) Expression of liver specific member of the 3β-hydroxysteroid dehydrogenase family, an isoform possessing an almost exclusive 3-keto steroid reductase activity. J. Biol. Chem., 267: 4513-4517. All publications 1992
363. Diamond, P., Cusan, L., Gomez, J.L., Bélanger, A., Labrie, F. (1996) Metabolic effects of 12-month percutaneous DHEA replacement therapy in postmenopausal women. J. Endocrinol., 150 Suppl.: S43-S50. All publications 1996
387. Dimitrakakis, C., Zhou, J., Wang, J., Belanger, A., Labrie, F., Cheng, C., Powell, D., Bondy, C. (2003) A physiologic role for testosterone in limiting estrogenic stimulation of the breast. Menopause, 10: 292-298. All publications 2003
3550. Dinel, S., Bolduc, C., Belleau, P., Boivin, A., Yoshioka, M., Calvo, E., Piedboeuf, B., Snyder, E.E., Labrie, F., St-Amand, J. (2005) Reproducibility bioinformatic analaysis and power of SAGE method to evaluate changes in transcriptome. Nucleic Acids Res., 33:e26: 1-8. All publications 2005
930. Dionne, P., Singh, S.M., Labrie, F. (1994) 1H and 13C nuclear magnetic resonance assignments and stereochemistry of N-n-butyl-n-methyl-11-(16'α-chloro-3',17'β (and 17α)-dihydroxyestra-1',4',5'(10')-trien-7α-yl) undecanamide. Steroids, 59: 493-497. All publications 1994
354. Donet, E., Bayo, P., Calvo, E., Labrie, F., Pérez, P. (2008) Identification of novel glucocorticoid receptor-regulated genes involved in epidermal homeostasis and hair follicle differentiation. J Steroid Biochem Mol Biol, 108: 8-16. All publications 2008
3551. Dosa, L., Sandler, H.M., Labrie, F., Kane, C. (2005) Prostate cancer management shows major shift in PSA era. Urol Times, 33: 9. All publications 2005
900. Doualla-Bell, F., Bonneau, M.J., Labrie, F., Fortier, M.A. (1995) Differential effects of a steroidal antiestrogen, EM-139, on prostaglandin and cAMP production in the circular and longitudinal layers of bovine myometrium. Biol. Reprod., 52: 1358-1363. All publications 1995
3825. Doualla-Bell, F., Lye, S.J., Labrie, F., Fortier, M.A. (1995) Differential expression and regulation of connexin-43 and cell-cell coupling in myocytes from the circular and longitudinal layers of bovine myometrium. Endocrinology, 136: 5322-5328. All publications 1995
772. Dufort, I., Labrie, F., Luu-The, V. (2001) Human types 1 and 3 3beta-hydroxysteroid dehydrogenases: differential lability and tissue distribution. J. Clin. Endocrinol. Metab., 86: 841-846. All publications 2001
95. Dufort, I., Soucy, P., Labrie, F., Luu-The, V. (1996) Molecular cloning of human type 3 3alpha-hydroxysteroid dehydrogenase that differs from 20alpha-hydroxysteroid dehydrogenase by seven amino acids. Biochem. Biophys. Res. Commun., 228: 474-479. All publications 1996
879. Dufort, I., Tremblay, Y., Bélanger, A., Labrie, F., Luu-The, V. (1996) Isolation and characterization of a stereospecific 3beta-hydroxysteroid sulfotransferase (pregnenolone sulfotransferase) cDNA. DNA Cell Biol., 15: 481-487. All publications 1996
504. Dumont, M., Dauvois, S., Simard, J., Garcia, T., Schachter, B., Labrie, F. (1989) Antagonism between estrogens and androgens on GCDFP-15 gene expression in ZR-75-1 cells and correlation between GCDFP-15 and estrogen as well as progesterone receptor expression in human breast cancer. J. Steroid Biochem., 34: 397-402. All publications 1989
3572. Dumont, M., Frank, D., Moisan, A.-M., Tranchant, M., Soucy, P., Breton, R., Labrie, F., Tavtigian, S.V., Simard, J. (2004) Structure of primate and rodent orthologs of the prostate cancer susceptibility gene ELAC2. Biochimica et Biophysica Acta, 1679: 230-247. All publications 2004
973. Dumont, M., Luu-The, V., de Launoit, Y., Labrie, F. (1992) Expression of human 17β-hydroxysteroid dehydrogenase in mammalian cells. J. Steroid Biochem. Mol. Biol., 41: 605-608. All publications 1992
368. Dumont, M., Luu-The, V., Dupont, E., Pelletier, G., Labrie, F. (1992) Characterization, expression and immunohistochemical localization of 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase in human skin. J. Invest. Dermatol., 99: 415-421. All publications 1992
166. Dupont, A., Boucher, H., Cusan, L., Lacourcière, Y., Emond, J., Labrie, F. (1990) Octreotide and bromocriptine in patients with stage D2 prostate cancer who relapsed during treatment with Flutamide and castration. Eur. J. Cancer, 26: 770-771. All publications 1990
157. Dupont, A., Cusan, L., Gomez, J.-L., Thibeault, M.M., Tremblay, M., Labrie, F. (1991) Prostatic specific antigen and prostatic acid phosphatase for monitoring therapy of carcinoma of the prostate. J. Urol., 146: 1064-1068. All publications 1991
132. Dupont, A., Cusan, L., Gomez, J.L., Koutsilieris, M., Suburu, R., Emond, J., Labrie, F. (1993) Combination therapy with Flutamide and the LHRH agonist [D-Trp6-des-Gly-NH2]LHRH ethylamide in stage C prostatic carcinoma. Br. J. Urol., 72: 629-634. All publications 1993
4027. Dupont, A., Dupont, P., Bélanger, A., Mailloux, J., Cusan, L., Labrie, F. (1990) Hormonal and biochemical changes during treatment of endometriosis with the luteinizing hormone-releasing hormone (LH-RH) agonist [D-Trp6,des-Gly-NH210]LH-RH ethylamide. Fertil. Steril., 54: 227-232. All publications 1990
993. Dupont, A., Dupont, P., Cusan, L., Tremblay, M., Gomez, J.L., Mailloux, J., de Lignières, B., Bélanger, A., Labrie, F. (1991) Efficacy of percutaneous estradiol and oral estrogens as replacement therapy in postmenopausal women, in : Dusitsin, N. et Notelovitz, M., eds: Physiological Hormone Replacement Therapy, New Jersey, USA, The Parthenon Publishing Group, pp 37-50. All publications 1991
133. Dupont, A., Gomez, J.L., Cusan, L., Koutsilieris, M., Labrie, F. (1993) Response to Flutamide withdrawal in advanced prostate cancer in progression under combination therapy. J. Urol., 150: 908-913. All publications 1993
3943. Dupont, A., Labrie, F., Cusan, L., Gomez, J.L., Tremblay, M., Lacourciere, Y., Emond, J., Monfette, G. (1992) Combination therapy with flutamide and castration (orchiectomy or LH-RH agonist) in untreated patients with advanced prostate cancer. Recent Results Cancer Res., 124: 43-54. All publications 1992
179. Dupont, A., Labrie, F., Manhès, G., Bergeron, N., Cusan, L., Pinault, S., Bélanger, A., Boucher, M., Lacourcière, Y., Emond, J. (1989) Combination therapy with Flutamide and the LHRH agonist [D-Trp6, des-Gly-NH210]LHRH ethylamide in stage C prostatic carcinoma, in: Labrie, F., Lee, F. et Dupont, A., eds: Early Stage Prostate Cancer: Diagnosis and Choice of Therapy, North Holland, Elsevier, ICS 841, pp 89-102. All publications 1989
3944. Dupont, A., Moorjani, S., Cusan, L., Dupont, P., De Lignières, B., Mailloux, J., Gomez, J.L., Labrie, F. (1992) Effect of progesterone on cholesterol and lipoproteins during hormonal replacement therapy, in: Lobo, R. et Naftolin, F., eds: Progesterone in Hormonal Replacement Therapy, New Jersey, USA, The Parthenon Publishing Group, pp 37-46. All publications 1992
3981. Dupont, A., Moorjani, S., Dupont, P., Cusan, L., Tremblay, M., Gomez, J.L., Mailloux, J., de Lignières, B., Bélanger, A., Labrie, F. (1991) Effects of percutaneous estradiol and oral replacement therapy on plasma low density lipoprotein, in: Dusitsin, N. et Notelovitz, M., eds: Physiological Hormone Replacement Therapy, New Jersey, USA, The Parthenon Publishing Group, pp 89-97. All publications 1991
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