Fernand Labrie

Publications

Page 3 of 26, showing 50 records out of 1263 total, starting on record 101, ending on 150

Publication Category Year
379. Liu, H., Zheng, S.F., Bellemare, V., Pelletier, G., Labrie, F., Luu-The, V. (2007) Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey. BMC Biochem, 8: 2 All publications 2007
356. Luu-The, V., Ferraris, C., Duche, D., Bélanger, P., Leclaire, J., Labrie, F. (2007) Steroid metabolism and profile of steroidogenic gene expression in EpiskinTM: High similarity with human epidermis. J Steroid Biochem Mol Biol 107: 30-36. All publications 2007
4714. Pelletier, G., Li, S., Luu-The, V., Labrie, F. (2007) Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. J Neuroendocrinol, 19: 426-431 All publications 2007
740. Pelletier, G., Luu-The, V., Li, S., Bujold, G., Labrie, F. (2007) Localization and glucocorticoid regulation of 11beta-hydroxysteroid dehydrogenase type 1 mRNA in the male mouse forebrain. Neuroscience, 145: 110-115. All publications 2007
741. Qiu, W., Zhou, M., Mazumdar, M., Azzi, A., Ghanmi, D., Luu-The, V., Labrie, F., Lin, S.-X. (2007) Structure-based inhibitor design for an enzymeTHAT binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol, 282: 8368-79. All publications 2007
9. Roy, J., Breton, R., Martel, C., Labrie, F., Poirier, D. (2007) Chemical synthesis and biological activities of 16alpha-derivatives of 5alpha-androstane-3alpha, 17beta-diol as antiandrogens. Bioorg Med Chem, 15: 3003-3018. All publications 2007
659. Sancéau, J.-Y., Larouche, D., Caron, B., Bélanger, P., Coquet, A., Bélanger, A., Labrie, F., Gauthier, S. (2007) Synthesis and deuterium labelling of the pure selective estrogen receptor modulator (SERM) acolbifene glucuronides. J. of Label Compd and Radiopharm, 50: 197-206. All publications 2007
10. Suzuki, K., Nishiyama, T., Hara, N., Yamana, K., Takahashi, K., Labrie, F. (2007) Importance of the intracrine metabolism of adrenal androgens in androgen-dependent prostate cancer. Prostate Cancer Prostatic Dis., 10: 301-6. All publications 2007
564. Swanson, C., Lorentzon, M., Vandenput, L., Labrie, F., Rane, A., Jakobsson, J., Chouinard, S., Bélanger, A., Ohlsson, C. (2007) Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y). J Clin Endocrinol Metab, 92: 3697-704. All publications 2007
11. Swanson, C., Mellström, D., Lorentzon, M., Vanderput, L., Jakobsson, J., Rane, A., Karlsson, M., Ljunggren, O., Smith, U., Eriksson, A.E., Bélanger, A., Labrie, F., Ohlsson, C. (2007) The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men. J Clin Endocrinol Metab, 92: 4878-4882. All publications 2007
12. Takase, Y., Luu-The, V., Poisson-Paré, D., Labrie, F., Pelletier, G. (2007) Expression of sulfotransferase 1E1 in human prostate as studied by in situ hybridization and immunocytochemistry. Prostate, 67: 405-409. All publications 2007
13. Tenta, R., Katopodis, H., Chatzïioannou, A., Pilalis, E., Calvo, E., Luu-The, V., Labrie, F., Kolisis, F., Koutsilieris, M. (2007) Microarray analysis of survival pathways in human PC-3 prostate cancer cells. Cancer Genomics Proteomics, 4: 309-18. All publications 2007
14. Vandenput, L., Labrie, F., Mellström, D., Swanson, C., Knutsson, T., Peeker, R., Ljunggren, O., Orwoll, E., Eriksson, A.L., Johnell, O., Damber, J.E., Ohlsson, C. (2007) Serum levels of specific glucuronidated androgen metabolites predict BMD and prostate volume in elderly men. J. of Bone and Mineral Research: The Official Journal of the American Soc. for Bone and Mineral Research, 22: 220-7. All publications 2007
567. Vandenput, L., Mellström, D., Lorentzon, M., Swanson, C., Karlsson, M.K., Brandberg, J., Lönn, L., Orwoll, E., Smith, U., Labrie, F., Ljunggren, O., Tivesten, A., Ohlsson, C. (2007) Androgens and glucuronidated androgen metabolites are associated with metabolic risk factors in men. J Clin Endocrinol Metab, 92: 4130-7. All publications 2007
357. Azzi, L., El-Alfy, M., Labrie, F. (2006) Gender differences and effects of sex steroids and dehydroepiandrosterone on androgen and oestrogen alpha receptors in mouse sebaceous glands. Br J Dermatol., 154: 21-7. All publications 2006
568. Bellemare, V., Labrie, F., Luu-The, V. (2006) Isolation and characterization of a cDNA encoding mouse 3beta-hydroxysteroid dehydrogenase an androgen-inactivating enzyme selectively expressed in female tissues. J Steroid Biochem Mol Biol, 98: 18-24. All publications 2006
15. Candas, B., Labrie, F., Gomez, J.L., Cusan, L., Chevrette, E., Levesque, J., Brousseau, G. (2006) Relationship among initial serum prostate specific antigen, prostate specific antigen progression and prostate cancer detection at repeat screening visits. J Urol, 175: 510-517. All publications 2006
569. Chouinard, S., Tessier, M., Vernouillet, G., Gauthier, S., Labrie, F., Barbier, O., Bélanger, A. (2006) Inactivation of the pure antiestrogen Fulvestrant and other synthetic estrogen molecules by UGT1A enzymes expressed in the breast tissue. Mol Pharmacol, 69: 908-20. All publications 2006
570. Compère, V., Ouellet, J., Luu-The, V., Dureuil, B., Tonon, M.C., Vaudry, H., Labrie, F., Pelletier, G. (2006) Role of androgens and glucocorticoids in the regulation of diazepam-binding inhibitor mRNA levels in male mouse hypothalamus. Brain Res. 1119: 50-7. All publications 2006
571. Eriksson, A.L., Lorentzon, M., Mellstrom, D., Vandenput, L., Swanson, C., andersson, N., Hammond, G.L., Jakobsson, J., Rane, A., Orwoll, E.S., Ljunggren, O., Johnell, O., Labrie, F., Windahl, S.H., Ohlsson, C. (2006) SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density. J Clin Endocrinol Metab, 91: 5029-37. All publications 2006
572. Faucher, F., Pereira de Jésus-Trans, K., Cantin, L., Luu-The, V., Labrie, F., Breton, R. (2006) Crystal structures of mouse 17beta-hydroxysteroid dehydrogenase (Apoenzyme and enzyme-NADP(H) binary complex): Identification of molecular determinants responsible for the unique 17beta-reductive activity of this enzyme. J.Mol. Biol., 364: 747-763. All publications 2006
573. Labrie, F. (2006) Dehydroepiandrosterone, androgens and the mammary gland. Gynecological Endocrinol: the official journal of the International Soc. of Gynecological Endocrinol, 22: 118-30. All publications 2006
380. Labrie, F. (2006) Future perspectives of selective estrogen receptor modulators used alone and in combination with DHEA. Endocr Relat Cancer, 13: 335-355. All publications 2006
16. Labrie, F. (2006) Keyrole of endocrinology in the victory against prostate cancer. Bull. Cancer, 93: 949-58. All publications 2006
576. Labrie, F., Bélanger, A., Bélanger, P., Bérubé, R., Martel, C., Cusan, L., Gomez, J., Candas, B., Castiel, I., Chaussade, V., Deloche, C., Leclaire, J. (2006) Androgen glucuronides, instead of testosterone, as the new markers of androgenic activity in women. J Steroid Biochem Mol Biol, 99: 182-188. All publications 2006
577. Labrie, F., Bélanger, A., Bélanger, P., Bérubé, R., Martel, C., Cusan, L., Gomez, J.L., Candas, B., Chaussade, V., Castiel, I., Deloche, C., Leclaire, J. (2006) Metabolism of DHEA in postmenopausal women following percutaneous administration. J Steroid Biochem Mol Biol, 103: 178-88. All publications 2006
578. Labrie, F., Luu-The, V., Martel, C., Chernomoretz, A., Calvo, E., Morissette, J., Labrie, C. (2006) Dehydroepiandrosterone (DHEA) is an anabolic steroid like dihydrotestosterone (DHT), the most potent natural androgen, and tetrahydrogestrinone (THG). J Steroid Biochem Mol Biol, 100: 52-8. All publications 2006
1097. Labrie, F., Poulin, R., Simard, J., Luu-The, V., Labrie, C., Bélanger, A. (2006) Androgens, DHEA and Breast Cancer, in: Tulandi, T. et Gelfand, M.M., eds: Androgens and Reproductive Aging, Oxsfordshire, UK, pp 113-135. All publications 2006
661. Lemieux, C., Gélinas, Y., Lalonde, J., Labrie, F., Richard, D., Deshaies, Y. (2006) Hypocholesterolemic action of the selective estrogen receptor modulator acolbifene in intact and ovariectomized rats with diet-induced hypercholesterolemia. Metabolism, 55: 605-13. All publications 2006
382. Liby, K., Rendi, M., Suh, N., Royce, D.B., Risingsong, R., Williams, C.R., Lamph, W., Labrie, F., Krajewsi, S., Xu, X., Kim, H., Brown, P., Sporn, M.B. (2006) The Combination of the Rexinoid, LG100268, and a SERM, either Arzoxifene or Acolbifene, Synergize in the Prevention and Treatment of Mammary Tumors in an Estrogen Receptor Negative Model of Breast Cancer. Clin Cancer Res, 12: 5902-5909. All publications 2006
383. Luu-The, V., Tremblay, P., Labrie, F. (2006) Characterization of type 12 17beta-hydroxysteroid dehydrogenase (17beta-HSD12), an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women. Molecular Endocrinology (Baltimore, Md.), 20: 437-43. All publications 2006
17. Perreira De Jésus, K., Côté, P.L., Cantin, L., Blanchet, J., Labrie, F., Breton, R. (2006) Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity. Protein Science: a publication of the Protein Society, 15: 987-99. All publications 2006
384. Song, D., Liu, G., Luu-The, V., Zhao, D., Wang, L., Zhang, H., Xueling, G., Li, S., Desy, L., Labrie, F., Pelletier, G. (2006) Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study. J Steroid Biochem Mol Biol, 101: 136-44. All publications 2006
18. Takase, Y., Lévesque, M.H., Luu-The, V., El-Alfy, M., Labrie, F., Pelletier, G. (2006) Expression of enzymes involved in estrogen metabolism in human prostate. J.Histochem Cytochem., 54: 911-21. All publications 2006
3544. Tchédam Ngatcha, B., Laplante, Y., Labrie, F., Luu-The, V., Poirier, D. (2006) 3 beta-Alkyl-androsterones as inhibitors of type 3 17 beta-hydroxysteroid dehydrogenase: Inhibitory potency in intact cells, selectivity towards isoforms 1, 2, 5 and 7, binding affinity for steroid receptors, and proliferative/antiproliferative activities on AR(+) and ER(+) cell lines. Mol. Cell Endocrinol, 248: 225-232. All publications 2006
580. Yoshioka, M., Boivin, A., Ye, P., Labrie, F., St-Amand, J. (2006) Effects of dihydrotestosterone on skeletal muscle transcriptome measured by serial analysis of gene expression. J Mol Endocrinol, 36: 247-259. All publications 2006
581. Azzi, L., El-Alfy, M., Martel, C., Labrie, F. (2005) Gender differences in mouse skin morphology and specific effects of sex steroids and dehydroepiandrosterone. J Invest Dermatol, 124: 22-7. All publications 2005
358. Berger, L., El-Alfy, M., Martel, C., Labrie, F. (2005) Effects of DHEA, Premarin and Acolbifene on histomorphology and sex steroid receptors of the rat vagina. J Steroid Biochem Mol Biol, 96: 201-15. All publications 2005
3549. Couture, J.-F., Pereira de Jésus-Trans, K., Roy, A.-M., Cantin, L., Côté, P.-L., Legrand, P., Luu-The, V., Labrie, F., Breton, R. (2005) Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen. Protein Science, 14: 1485-1497. All publications 2005
3550. Dinel, S., Bolduc, C., Belleau, P., Boivin, A., Yoshioka, M., Calvo, E., Piedboeuf, B., Snyder, E.E., Labrie, F., St-Amand, J. (2005) Reproducibility bioinformatic analaysis and power of SAGE method to evaluate changes in transcriptome. Nucleic Acids Res., 33:e26: 1-8. All publications 2005
3551. Dosa, L., Sandler, H.M., Labrie, F., Kane, C. (2005) Prostate cancer management shows major shift in PSA era. Urol Times, 33: 9. All publications 2005
663. Gauthier, S., Cloutier, J., Dory, Y.L., Favre, A., Mailhot, J., Ouellet, C., Schwerdteeger, A., Mérand, Y., Martel, C., Simard, J., Labrie, F. (2005) Synthesis and structure-activity relationships of analogs of EM-652 (acobifene), a pure selective estrogen receptor modulator. Study of mitrogen substitution. J of Enzyme Inhibition and Medicinal Chemistry, 20: 165-177. All publications 2005
19. Labrie, F., Bélanger, A., Luu-The, V., Labrie, C., Simard, J., Cusan, L., Gomez, J., Candas, B. (2005) Gonadotropin-releasing hormone agonists in the treatment of prostate cancer. Endocrine Reviews, 26: 361-379. All publications 2005
20. Labrie, F., Luu-The, V., Bélanger, A., Lin, S.-X., Simard, J., Pelletier, G., Labrie, C. (2005) Is DHEA a hormone? Starling Review. J Endocrinol, 187: 169-196. All publications 2005
3555. Labrie, F., Luu-The, V., Calvo, E., Martel, C., Cloutier, J., Gauthier, S., Belleau, P., Boucher, H., Morissette, J., Lévesque, M.H., Labrie, C. (2005) Tetrahydrogestrione (THG) induces a genomic signature typical of a potent anabolic steroid. J Endocrinol, 184: 427-33. All publications 2005
664. Lemieux, C., Gélinas, Y., Lalonde, J., Labrie, F., Cianflone, K., Deshaies, Y. (2005) Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-B1 and LDL receptors. J. of Lipid Research, 46: 1285-94. All publications 2005
665. Lemieux, C., Gélinas, Y., Lalonde, J., Labrie, F., Richard, D., Deshaies, Y. (2005) The selective estrogen receptor modulator acolbifene reduces cholesterolemia idependently of its anorectic action in control and cholesterol-fed rats. J Nutr, 135: 2225-9. All publications 2005
666. Lemieux, C., Phaneuf, D., Labrie, F., Giguère, V., Richard, D., Deshaies, Y. (2005) Estrogen receptor alpha-mediated adiposity-lowering and hypocholesterolemic actions of the selective estrogen receptor modulator acolbifene. Int J Obes, 29: 1236-44. All publications 2005
3560. Luu-The, V., Pelletier, G., Labrie, F. (2005) Quantitative appreciation of steroidogenic gene expression in mouse tissue: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase. J Steroid Biochem Mol Biol, 93: 269-76. All publications 2005
3561. Maltais, R., Mercier, C., Labrie, F., Poirier, D. (2005) Solid-phase synthesis of model libraries of 3alpha, 17beta-dihydroxy-16alpha-(aminoethyl-N-substituted)-5alpha-androstanes for the development of steroidal therapeutic agents. Molecular Diversity, 9: 67-79. All publications 2005
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