Fernand Labrie

Publications

Page 5 of 26, showing 50 records out of 1263 total, starting on record 201, ending on 250

Publication Category Year
3613. Pelletier, G., Luu-The, V., Li, S., Ren, L., Labrie, F. (2003) Morphological studies of prolactin-secreting cells in estrogen receptor alpha and estrogen receptor beta knockout mice. Neuroendocrinol, 77: 324-333. All publications 2003
3612. Pelletier, G., Luu-The, V., Li, S., Ren, L., Labrie, F. (2003) Sex-related expression of 20alpha-hydroxysteroid dehydrogenase mRNA in the adult mouse. J. Histochem. Cytochem., 51 (11): 1425-1436. All publications 2003
392. Roy, J., Couillard, C., Gutman, M., Labrie, F. (2003) A novel pure SERM achieves complete regression of the majority of human breast cancer tumors in nude mice. Breast Cancer Res Treat, 81: 223-229. All publications 2003
32. Simard, J., Dumont, M., Labuda, D., Sinnett, D., Meloche, C., El Alfy, M., Berger, L., Lees, E., Labrie, F., Tavtigian, S.V. (2003) Prostate cancer susceptibility genes: lessons learned and challenges posed. Endocrine Related Cancer, 10: 225-259. All publications 2003
3616. Sullivan, D.A., Bélanger, A., Cermak, J.M., Bérubé, R., Papas, A.S., Sullivan, R.M., Yamagami, H., Dana, M.R., Labrie, F. (2003) Are women with Sjögren's Syndrome androgen-deficient? Journal of Rheumatology, 30: 2413-2419. All publications 2003
676. Tatchum-Talom, R., Martel, C., Labrie, F., Marette, A. (2003) Acute vascular effects of the selective estrogen receptor modulator EM-652 (SCH 57068) in the rat mesenteric vascular bed. J. of the European Soc. of Cardiology, 57: 535-543. All publications 2003
677. Bernardi, F., Stomati, M., Luisi, S., Pieri, M., Labrie, F., Geneazzani, A.R. (2002) Effects of the new generation selective estrogen receptor modulator EM-652 and oral administration of estradiol valerate on circulating, brain, and adrenal beta-endorphin and allopregnanolone levels in intact fertile and ovariectomized rats. Fertility and Sterility, 77: 1018-1027. All publications 2002
3619. Couture, J.-F., Cantin, L., Legrand, P., Luu-The, V., Labrie, F., Breton, R. (2002) Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates. Acta Cryst. D. Biol. Crystallogr., D58: 135-139. All publications 2002
393. Gutman, M., Couillard, S., Roy, J., Labrie, F., Candas, B., Labrie, C. (2002) Comparison of the effects of EM-652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast tumors in nude mice. International Journal of Cancer, 99: 273-278. All publications 2002
33. Labrie, F. (2002) Androgen blockade in prostate cancer in 2002: major benefits on survival in localized disease. Mol Cell Endocrinol, 198: 77-87. All publications 2002
34. Labrie, F. (2002) Endocrine-sensitive cancers of the prostate and breast, in: Baster, J., Melmed, S. et New, M., eds: Genetics in Endocrinology, Lippincott-William and Wilkins, pp 607-661. All publications 2002
395. Labrie, F., Bélanger, A., Luu-The, V., Simard, J., Labrie, C. (2002) DHEA replacement therapy as a source of androgens and estrogens at menopause, in: Genazzani, A.R., Petraglia, F. et Artini, P.G., eds: Advances in Gynecological Endocrinology, Florence, Italy, Parthenon Publishing, pp 249-258. All publications 2002
3625. Labrie, F., Candas, B. (2002) Letter to the Editor. Re: Does PSA reduce prostate cancer mortality?-Interpreting the Quebec Prostate Cancer Study. CMAJ, 167: 340. All publications 2002
35. Labrie, F., Candas, B., Gomez, L.J., Cusan, L. (2002) Can combined androgen blockade provide long term control or possible cure of localized prostate cancer? Urology, 60: 115-119. All publications 2002
396. Labrie, F., Labrie, C., Bélanger, A., Simard, J. (2002) Third and fourth generation SERMs, in: Manni, A. et Verderame, M., eds: Selective Estrogen Receptor Modulators: Research and Clinical Applications, Totowa, NJ, Humana Press Inc., pp 167-187. All publications 2002
601. Leblanc, M., Labrie, C., Bélanger, A., Candas, B., Labrie, F. (2002) Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey. J. Steroid Biochemistry & Molecular Biology, 81: 159-164. All publications 2002
3629. Simard, J., Dumont, M., Soucy, P., Labrie, F. (2002) Perspective: Prostate Cancer Susceptibility Genes. Endocrinology, 143: 2029-2040. All publications 2002
682. Simoncini, T., Varone, G., Fornari, L., Mannella, P., Labrie, F., Genazzani, A.R. (2002) Genomic and non-genomic mechanisms of nitric oxide synthesis induction in human endothelial cells by a fourth generation selective estrogen receptor modulator. J. Endocrinol, 143: 2052-2061. All publications 2002
669. Barbier, O., Albert, C., Martineau, I., Vallée, M., High, K., Labrie, F., Hum, D.W., Labrie, C., Bélanger, A. (2003) Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068) by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes. Mol Pharmacol, 59: 636-45. All publications 2001
3632. Brawer, M.K., Crawford, E.D., Labrie, F., Mendoza-Valdz, A., Miller, P.D., Petrylak, D.P. (2001) Androgen deprivation and other treatments for advanced prostate cancer. Reviews in Urology, 3: S59-S68. All publications 2001
36. Crawford, E.D., Miller, G., Labrie, F., Hirano, D., Batuello, J., Globe, M. (2001) Prostate cancer pathology, screening and epidemiology. Reviews in Urology, 3: S2-S10. All publications 2001
772. Dufort, I., Labrie, F., Luu-The, V. (2001) Human types 1 and 3 3beta-hydroxysteroid dehydrogenases: differential lability and tissue distribution. J. Clin. Endocrinol. Metab., 86: 841-846. All publications 2001
37. Gomella, L.G., Labrie, F., Gamito, E.J., Brawer, M.K. (2001) Prostate cancer: risk assessment and diagnostic approaches. Reviews in Urology, 3: S31-S38. All publications 2001
4717. Labrie, F. (2001) Dehydroepiandrosterone (DHEA) as potential hormone replacement therapy. Références en Gynecologie Obstétrique, 8: 317-322. All publications 2001
38. Labrie, F. (2001) Le cancer de la prostate: blocage combiné des androgènes comme traitement à tous les stades de la maladie. Oncologie, 3: 3-12. All publications 2001
774. Labrie, F. (2001) Prostate cancer: Endocrinology of prostate cancer - intracrinology, in: Pinchera, A., Bertega, X., Binder, C., Fischer, J. et Braverman, L., eds: Endocrinology and Metabolism, pp 13-16. All publications 2001
3637. Labrie, F. (2001) The Role of Androgen Therapy in Postmenopausal Women - Physiology of Androgens in Women. Supplement to Menopause Management, 11: 3-5. All publications 2001
3638. Labrie, F. (2001) Unique role of hormone therapy in the management of prostate cancer at all stages of the disease, in: Syrigos, K.N., ed. Prostate cancer: biology, diagnosis and management, pp 301-314. All publications 2001
399. Labrie, F., Bélanger, A., Luu-The, V., Simard, J., Labrie, C. (2001) DHEA replacement therapy as source of androgens and estrogens at menopause, in: Genazani, A.R., Petraglia, F. et Artini, P.G., eds: Advances in Gynecological Endocrinology, London, UK, Parthenon Publishing, pp 249-258. All publications 2001
39. Labrie, F., Candas, B., Cusan, L., Gomez, J.L. (2001) The Laval University screening trial results (Chapter 17), in: Thompson, I.M., Resnick, M.I. et Klein, E.A., eds: Current Clinical Urology, Prostate Cancer Screening, Totowa, NJ, Humana Press Inc., pp 255-279. All publications 2001
3643. Labrie, F., Candas, B., Cusan, L., Gomez, J.L., Lévesque, J., Chevrette, E., Brousseau, G. (2001) Prostate Cancer Screening: The Only Way to Early Treatment and a Major Impact on Survival. Proceeding of the VIIth International Congress of Andrology, 461-468. All publications 2001
400. Labrie, F., Labrie, C., Bélanger, A., Giguère, V., Simard, J., Mérand, Y., Gauthier, S., Luu-The, V., Candas, B., Martel, C.E.A. (2001) Pure selective estrogen receptor modulators, new molecules having absolute cell specificity ranging from pure antiestrogenic to complete estrogen-like activities, in: Scolnick, E.M., ed. Advances in Protein Chemistry, San Diego, CA, Academic Press, pp 293-368. All publications 2001
401. Labrie, F., Labrie, C., Bélanger, A., Simard, J., Giguère, V., Tremblay, A., Tremblay, G. (2001) EM-652 (SCH 57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium. J. Steroid Biochem. Mol. Biol., 79: 213-225. All publications 2001
40. Labrie, F., Luu-The, V., Labrie, C., Simard, J. (2001) DHEA and its transformation into androgens and estrogens in peripheral target tissues: Intracrinology. Neuroendocrinologie, 22: 185-212. All publications 2001
403. Labrie, F., Simard, A.R., Labrie, C., Bélanger, A. (2001) EM-652 (SCH57068) a pure SERM in the mammary gland and endometrium. Référence en Gynécologie Obstétrique, 8: 331-336. All publications 2001
781. Luu-The, V., Dufort, I., Pelletier, G., Labrie, F. (2001) Type 5 17beta-hydroxysteroid dehydrogenase: its role in the formation of androgens in women. Mol. Cell. Endocrinol., 171: 77-82. All publications 2001
3650. Nahoum, V., Gangloff, A., Legrand, P., Zhu, D.-W., Cantin, L., Zhorov, B., Luu-The, V., Labrie, F., Breton, R., Lin, S.-X. (2001) Structure of the human 3 alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25 a resolution. J. of Biological Chemistry, 276: 41091-98. All publications 2001
404. Pelletier, G., El Alfy, M., Labrie, C., Martel, C., Labrie, F. (2001) Effect of long-term treatment with the antiestrogen EM-652.HCl on pituitary estrogen receptor alpha and prolactin mRNA expression in intact, ovariectomized and GnRH-treated female rats. Neuroendocrinology, 74: 367-374. All publications 2001
3652. Pelletier, G., Labrie, C., Martel, C., Li, S., Labrie, F. (2001) Role of extra-ovarian estrogens in the regulation of GnRH mRNA expression in the rat brain. J. Neuroendocrinol, 13: 678-682. All publications 2001
3653. Pelletier, G., Li, S., Luu-The, V., Tremblay, Y., Bélanger, A., Labrie, F. (2001) Immunoelectron microscopic localization of three key steroidogenic enzymes (cytochrome P450scc, 3beta-hydroxysteroid dehydrogenase and cytochrome P450c17) in rat adrenal cortex and gonads. J Endocrinology, 171: 373-383. All publications 2001
41. Pelletier, G., Luu-The, V., El Alfy, M., Li, S., Labrie, F. (2001) Immunoelectron microscopic localization of 3beta-hydroxysteroid dehydrogenase and type 5 17beta-hydroxysteroid dehydrogenase in the human prostate and mammary gland. J. Mol. Endocrinol., 26: 11-19. All publications 2001
42. Roach III, M.J., Thrasher, J.B., Blasko, J., Raben, D., Stone, N., Katz, A., Labrie, F. (2001) Prostatectomy, brachytherapy, intensity modulated radiotherapy, hormonal-radiotherapy, salvae cryosurgery and the role of combined hormonal blokade in the treatment of prostate cancer. Reviews in Urology, 3: S49-S58. All publications 2001
406. Sauvé, F., McBroom, L.D.B., Gallant, J., Moraitis, A.N., Labrie, F., Giguère, V. (2001) CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant. Mol. Cell. Biol, 21: 343-353. All publications 2001
3657. Singh, R., Eeles, R.A., Durocher, F., Simard, J., Edwards, S., Bodzioch, M., Teare, D., Ford, D., Dearnaley, D., Ardern-Jones, A., Labrie, F. (2001) High risk genes predisposing to prostate cancer development-do they exist? Prostate cancer and prostatic diseases, 3: 241-247. All publications 2001
43. Tavtigian, S.V., Simard, J., Teng, D.H.F., Abtin, V., Baumgard, M., Beck, A., Camp, N.J., Carillo, A.R., Chen, Y., Dayananth, P., Desrochers, M., Dumont, M., Farnham, J.M., Frank, D., Frye, C., Ghaffari, S., Gupte, J.S., Hu, R., Iliev, D., Janecki, T., Kort, E.N., Laity, K.E., Leavitt, A., Leblanc, G., McArthur-Morrison, J., Pederson, A., Penn, B., Peterson, K.T., Reid, J.E., Richards, S., Schroeder, M., Smith, R., Snyder, S.C., Swedlund, B., Swensen, J., Thomas, A., Tranchant, M., Woodland, A.-M., Labrie, F., Skolnick, M.H., Neuhausen, S., Rommens, J., Cannon-Albright, L.A. (2001) A candidate prostate cancer susceptibility gene at chromosome 17p. Nat. Genet., 27: 172-180. All publications 2001
3659. Zhu, D.-W., Cantin, L., Nahoum, V., Rehse, P., Luu-The, V., Labrie, F., Breton, R., Lin, S.-X. (2001) Crystallization and preliminary X-ray crystallographic analysis of the human type 3 3beta-hydroxysteroid dehydrogenase at 1.8 Å resolution. Acta Crystallogr. D., D57: 589-591. All publications 2001
605. Boivin, R.P., Luu-The, V., Lachance, R., Labrie, F., Poirier, D. (2000) Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase. J. Med. Chem., 43: 4465-4478. All publications 2000
44. Candas, B., Cusan, L., Gomez, J.-L., Diamond, P., Suburu, R.E., Lévesque, J., Brousseau, G., Bélanger, A., Labrie, F. (2000) Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer. Prostate, 45: 19-35. All publications 2000
407. Couillard, S., Labrie, C., Gauthier, S., Mérand, Y., Singh, S.M., Candas, B., Labrie, F. (2000) Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice. Int. J. Cancer, 85: 424-429. All publications 2000
45. El-Alfy, M., Pelletier, G. Hermo, L.S., Labrie, F. (2000) Unique features of the basal cells of human prostate epithelium. Microsc. Res. Tech., 51: 436-446. All publications 2000
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