Fernand Labrie

Publications

Page 8 of 26, showing 50 records out of 1263 total, starting on record 351, ending on 400

Publication Category Year
963. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Labrie, C., Dupont, E., Martel, C., Couet, J., Trudel, C., Rhéaume, E., Breton, N., de Launoit, Y., Dumont, M., Zhao, H.F., Lachance, Y. (1993) Structure and control of expression of the 3β-HSD and 17β-HSD genes in classical steroidogenic and peripheral intracrine tissues, in: Leung, P.C.K., Hsueh, A.J.W. et Friesen, H.G., eds: Molecular Basis of Reproductive Endocrinology, New York, Karger, pp 112-143. All publications 1993
1003. Labrie, F., Simard, J., Luu-The, V., Trudel, C., Martel, C., Labrie, C., Zhao, H.F., Rhéaume, E., Couet, J., Breton, N. (1991) Expression of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase (3beta-HSD) and 17beta-hydroxysteroid dehydrogenase (17beta-HSD) in adipose tissue. Int. J. Obstet., 15 Suppl. 2: 91-99. All publications 1991
492. Labrie, F., Simard, J., Poulin, R., Hatton, A.C., Labrie, C., Dauvois, S., Zhao, H., Petitclerc, L., Couet, J., Dumont, M., Haagensen D.E. (1990) Potent antagonism between estrogens and androgens on GCDFP-15 expression and cell growth in the ZR-75-1 human breast cancer cells. In: Angeli, A., Bradlow, H., Chasalow, F.I. et Dogliotti, L. eds. Workshop on Biochemistry of Breast Cyst Fluid and Cancer Risk. Ann. N.Y. Acad. Sci. 586: 174-187. All publications 1990
86. Labrie, F., Simard, J., Singh, S.M., Candas, B. (1997) Estimated potency of Casodex: A problematic design [Letter to the Editor re Schellhammer et al. 45: 745-52, 1995]. Urology, 50: 309-313. All publications 1997
981. Labrie, F., Sugimoto, Y., Luu-The, V., Simard, J., Lachance, Y., Bachvarov, D., Leblanc, G., Durocher, F., Paquet, N. (1992) Structure of human type II 5α-reductase gene. Endocrinology, 131: 1571-1573. All publications 1992
421. Labrie, F.; (1999). EM-652: a pure anti-estrogen discovered and developed in Canada. The best hope for breast cancer prevention and treatment. Can. Breast Cancer Network, 4: Vol. 4, p. 7. All publications 1999
640. Labrie, Y., Couet, J., Simard, J., Labrie, F. (1994) Multihormonal regulation of dehydroepiandrosterone sulfotransferase mRNA levels in adult rat liver. Endocrinology, 134: 1693-1699. All publications 1994
908. Labrie, Y., Durocher, F., Lachance, Y., Turgeon, C., Simard, J., Labrie, C., Labrie, F. (1995) The human type II 17beta-hydroxysteroid dehydrogenase gene encodes two alternatively-spliced messenger RNA species. DNA Cell Biol., 14: 849-861. All publications 1995
1034. Lachance, Y., Luu-The, V., Labrie, C., Simard, J., Dumont, M., de Launoit, Y., Guérin, S., Leblanc, G., Labrie, F. (1990) Characterization of human 3beta-hydroxysteroid dehydrogenase/delta5/delta4-isomerase gene and its expression in mammalian cells. J. Biol. Chem, 265: 20469-20475. All publications 1990
1004. Lachance, Y., Luu-The, V., Verreault, H., Dumont, M., Rhéaume, E., Leblanc, G., Labrie, F. (1991) Structure of human 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase (3beta-HSD) gene-adrenal and gonadal specificity. DNA Cell Biol., 10: 701-711. All publications 1991
174. Lacoste, D., Bélanger, A., Labrie, F. (1990) Biosynthesis and degradation of androgens in human prostatic cancer cell lines. In: Bradlow, H., Castagnetta, L., d'Aquino, S. et Labrie, F., eds. Steroid Formation, Degradation and Action in Peripheral Tissues Normal and Neoplastic Tissues. Ann. New York Acad. Sci. pp 389-391. All publications 1990
175. Lacoste, D., Candas, B., Normand, M., Labrie, F. (1990) Model of the distribution and metabolism of a GnRH superagonist in dogs. Am. J. Physiol., 258: E468-E475. All publications 1990
3803. Laflamme, N., Leblanc, J.F., Mailloux, J., Faure, N., Labrie, F., Simard, J. (1996) Mutation R96W in cytochrome P450C17 gene causes combined 17beta-hydroxylase/17-20 lyase deficiency in two french canadian patients. J. Clin. Endocrinol. Metab., 81: 264-268. All publications 1996
493. Laquerre, S., Poulin, R., Labrie, F., Chafouleas, J.G. (1990) Identification of a 51-kilodalton calmodulin binding protein that changes during estrogen-stimulated cell growth. Biochem. Cell Biol., 68: 863-869. All publications 1990
3583. Larose, M., St-Amand, J., Yoshioka, M., Morissette, J., Labrie, C., Raymond, V., Labrie, F. (2004) Transcriptome of mouse uterus by Serial Analysis of Gene Expression: comparison with skeletal muscle. Mol Reprod Dev, 68: 142-148. All publications 2004
87. Laverdiere, J., Gomez, J.L., Cusan, L., Suburu, R.E., Diamond, P., Lemay, M., Candas, B., Fortin, A., Labrie, F. (1997) Beneficial effect of combination therapy administered prior to, during and following external beam radiation therapy in localized prostate cancer. Int. J. Radiat. Oncol. Biol. Phys., 37: 247-252. All publications 1997
3584. Leblanc, M., Bélanger, M.C., Julien, P., Tchernof, A., Labrie, C., Bélanger, A., Labrie, F. (2004) Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal and combined androgen blockade conditions. J. of Clinical Endocrinology and Metabolism, 89: 1849-1857. All publications 2004
601. Leblanc, M., Labrie, C., Bélanger, A., Candas, B., Labrie, F. (2002) Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey. J. Steroid Biochemistry & Molecular Biology, 81: 159-164. All publications 2002
596. Leblanc, M., Labrie, C., Bélanger, A., Candas, B., Labrie, F. (2003) Bioavailability and pharmacokinetics of dehydroepiandrosterone in the cynomolgus monkey. J Clin Endocrinol Metab, 88 (9): 4293-302. All publications 2003
664. Lemieux, C., Gélinas, Y., Lalonde, J., Labrie, F., Cianflone, K., Deshaies, Y. (2005) Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-B1 and LDL receptors. J. of Lipid Research, 46: 1285-94. All publications 2005
665. Lemieux, C., Gélinas, Y., Lalonde, J., Labrie, F., Richard, D., Deshaies, Y. (2005) The selective estrogen receptor modulator acolbifene reduces cholesterolemia idependently of its anorectic action in control and cholesterol-fed rats. J Nutr, 135: 2225-9. All publications 2005
661. Lemieux, C., Gélinas, Y., Lalonde, J., Labrie, F., Richard, D., Deshaies, Y. (2006) Hypocholesterolemic action of the selective estrogen receptor modulator acolbifene in intact and ovariectomized rats with diet-induced hypercholesterolemia. Metabolism, 55: 605-13. All publications 2006
666. Lemieux, C., Phaneuf, D., Labrie, F., Giguère, V., Richard, D., Deshaies, Y. (2005) Estrogen receptor alpha-mediated adiposity-lowering and hypocholesterolemic actions of the selective estrogen receptor modulator acolbifene. Int J Obes, 29: 1236-44. All publications 2005
597. Lemieux, C., Picard, F., Labrie, F., Richard, D., Deshaies, Y. (2003) The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity. Obes. Res., 11: 477-490. All publications 2003
3585. Lepine, J., Bernard, O., Plante, M., Tetu, B., Pelletier, G., Labrie, F., Bélanger, A., Guillemette, C. (2004) Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium. J. of Clinical Endocrinology and Metabolism, 89: 5222-5232. All publications 2004
8. Levesque, M.H., El-Alfy, M., Berger, L., Labrie, F., Labrie, C. (2007) Evaluation of AIbZIP and Cdc47 as Markers for Human Prostatic Diseases. Urology, 69: 196-201. All publications 2007
460. Li, S., Lévesque, C., Geng, C.S., Yan, X., Labrie, F. (1995) Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 34: 147-159. All publications 1995
475. Li, S., Lepage, M., Mérand, Y., Bélanger, A., Labrie, F. (1992) Growth inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by controlled-release low-dose medroxyprogesterone acetate. Breast Cancer Res. Treat., 24: 127-137. All publications 1992
464. Li, S., Martel, C., Dauvois, S., Bélanger, A., Labrie, F. (1994) Effect of estrone on the growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat: a model of post-menopausal breast cancer. Endocrinology, 134: 1352-1357. All publications 1994
470. Li, S., Yan, X., Bélanger, A., Labrie, F. (1993) Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(?)anthracene (DMBA) in the rat. Breast Cancer Res. Treat., 29: 203-217. All publications 1993
3886. Li, S., Yan, X., Bélanger, A., Labrie, F. (1993) Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(a)antrhracene (DMBA) in the rat. Breast Cancer Res Treat, 29: 203-217. All publications 1993
910. Li, X., Chen, C., Singh, S.M., Labrie, F. (1995) The enzyme and inhibitors of 4-ene-3-oxosteroid 5alpha-reductase. Steroids, 60: 430-441. All publications 1995
116. Li, X., Singh, S.M., Côté, J., Laplante, S., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro evaluation of 4-substituted-N-(1,1-dimethylethyl)-3-oxo-4-androsten-17beta-carboxamides as 5alpha-reductase inhibitors and antiendrogens. J. Med. Chem., 38: 1456-1461. All publications 1995
3887. Li, X., Singh, S.M., Labrie, F. (1994) A convenient and practical method for conversion of primary alkyl chlorides to highly pure bromides (>99%). Synthetic Communic. 24: 733-743. All publications 1994
937. Li, X., Singh, S.M., Labrie, F. (1994) Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium (III) chloride: synthesis of 17β-propyl-17β-hydroxy-4-androsten-3-one, an androgen receptor antagonist. Tetrahedron Lett., 35: 1157-1160. All publications 1994
117. Li, X., Singh, S.M., Labrie, F. (1995) Synthesis and in vitro activity of 17beta-(N-alkyl)formamido/ alkylamido-4-aza-/4-methyl-4-aza-3-oxo-5beta-androstan-3-ones as inhibitors of human 5alpha-reductase and antagonists on the androgen receptor. J. Med. Chem., 38: 1158-1173. All publications 1995
118. Li, X., Singh, S.M., Lourdusamy, M., Mérand, Y., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro antiandrogenic activity of 17beta-hydroxy-17beta-(w-hydroxy/haloalkyn-1'-yl)-4-methyl-4-aza-3-oxo-5beta-androstan-(1-ene)-3-ones. Bioorg. Med. Chem. Lett., 5: 1061-1064. All publications 1995
886. Li, X., Singh, S.M., Luu-The, V., Côté, J., Laplante, S., Labrie, F. (1996) Vinyl fluoride as a mimic of the "intermediate" enol form in the 5alpha-reductase transformation: synthesis and in vitro activity of (N-1',1'-dimethylethyl)-3-haloandrost-3,5-diene-17beta-carboxamides. Bioorg. Med. Chem., 4: 55-60. All publications 1996
4698. Li, Z., Luu-The, V., Poisson-Paré, D., Ouellet, J., Li, S., Labrie, F., Pelletier, G. (2009) Expression of enzymes involved in synthesis and metabolism of estradiol in human breast as studied by immunocytochemistry and in situ hybridization. Histol Histopathol, 24: 273-282. All publications 2009
382. Liby, K., Rendi, M., Suh, N., Royce, D.B., Risingsong, R., Williams, C.R., Lamph, W., Labrie, F., Krajewsi, S., Xu, X., Kim, H., Brown, P., Sporn, M.B. (2006) The Combination of the Rexinoid, LG100268, and a SERM, either Arzoxifene or Acolbifene, Synergize in the Prevention and Treatment of Mammary Tumors in an Estrogen Receptor Negative Model of Breast Cancer. Clin Cancer Res, 12: 5902-5909. All publications 2006
982. Lin, S.-X., Yang, F., Jin, J.-Z., Breton, R., Zhu, D.-W., Luu-The, V., Labrie, F. (1992) Subunit identity of the dimeric 17β-hydroxysteroid dehydrogenase from human placenta. J. Biol. Chem., 267: 16182-16187. All publications 1992
887. Lin, S.-X., Zhu, D.-W., Azzi, A., Campbell, R.L., Breton, R., Labrie, F., Ghosh, D., Pletnev, V., Duax, W.L., Pangborn, W. (1996) Studies on the 3D-structure of estrogenic 17beta-hydroxysteroid dehydrogenase. J. Endocrinol., 150 Suppl.: S13-S20. All publications 1996
561. Liu, H., Bellemare, V., Labrie, F., Luu-The, V. (2007) Molecular characterization of the cynomolgus monkey Macaca fascicularis steroidogenic enzymes belonging to the aldo-keto reductase family. J Steroid Biochem Mol Biol, 104: 75-80. All publications 2007
737. Liu, H., Zheng, S.F., Bellemare, V., Pelletier, G., Labrie, F., Luu-The, V. (2007) Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey. BMC Biochem, 8: 1-9. All publications 2007
379. Liu, H., Zheng, S.F., Bellemare, V., Pelletier, G., Labrie, F., Luu-The, V. (2007) Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey. BMC Biochem, 8: 2 All publications 2007
888. Lopez-Solache, I., Luu-The, V., Séralini, G.E., Labrie, F. (1996) Heterogeneity of rat type I 5alpha-reductase cDNA: cloning, expression and regulation by pituitary implants and dihydrotestosterone. Biochim. Biophys. Acta, 1305: 139-144. All publications 1996
857. Lourdusamy, M., Coté, J., Laplante, S., Labrie, F., Singh, S.M. (1997) Synthesis and in vitro Study of 17beta-(N-Ureylne-N, N'-disubstituted)-4-methyl-4Aza-5alpha-androstan-3-ones as Selective Inhibitors of Type I 5alpha-Reductase. Bioorg. Med. Chem., 5: 305-310. All publications 1997
3845. Lourdusamy, M., Labrie, F., Singh, S.M. (1995) Synthesis of Atamestane (SH 489): An aromatase inhibitor. Synth. Comm., 25: 3655-3662. All publications 1995
88. Luo, S., Chen, C., Labrie, C., Candas, B., Singh, S.M., Labrie, F. (1997) Daily dosing with Flutamide or Casodex exerts maximal antiandrogenic activity. Urology, 50: 913-919. All publications 1997
428. Luo, S., Labrie, C., Bélanger, A., Candas, B., Labrie, F. (1998) Prevention of development of dimenthylbenz(a)anthracene (DMBA)-induced mammary tumors in the rat by the new nonsteroidal antiestrogen EM-800 (SCH 57050). Breast Cancer Res. Treat., 49: 1-11. All publications 1998
<< previous | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 next >>

Biography  |  Publications  |  Scientific Conferences  |  Selected Slide Presentations  |  Awards